Search Results - "FUJINO, H"

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    SLCO1B1 (OATP1B1, an Uptake Transporter) and ABCG2 (BCRP, an Efflux Transporter) Variant Alleles and Pharmacokinetics of Pitavastatin in Healthy Volunteers by Ieiri, I, Suwannakul, S, Maeda, K, Uchimaru, H, Hashimoto, K, Kimura, M, Fujino, H, Hirano, M, Kusuhara, H, Irie, S, Higuchi, S, Sugiyama, Y

    Published in Clinical pharmacology and therapeutics (01-11-2007)
    “…To investigate the contribution of genetic polymorphisms of SLCO1B1 and ABCG2 to the pharmacokinetics of a dual substrate, pitavastatin, 2 mg of pitavastatin…”
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    Journal Article
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    TRPM8 has a key role in experimental colitis‐induced visceral hyperalgesia in mice by Hosoya, T., Matsumoto, K., Tashima, K., Nakamura, H., Fujino, H., Murayama, T., Horie, S.

    Published in Neurogastroenterology and motility (01-08-2014)
    “…Background Transient receptor potential channel melastatin 8 (TRPM8) is activated by cold temperatures and cooling agents (menthol and icilin). Recent studies…”
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    Protective effects of astaxanthin on capillary regression in atrophied soleus muscle of rats by Kanazashi, M., Okumura, Y., Al-Nassan, S., Murakami, S., Kondo, H., Nagatomo, F., Fujita, N., Ishihara, A., Roy, R. R., Fujino, H.

    Published in Acta Physiologica (01-02-2013)
    “…Aim The capillary regression in skeletal muscles associated with a chronic decrease in activity is related to a dysfunction of endocapillary cells induced by…”
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    Journal Article
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    Lack of exercise, via hindlimb suspension, impedes endogenous neurogenesis by Yasuhara, T, Hara, K, Maki, M, Matsukawa, N, Fujino, H, Date, I, Borlongan, C.V

    Published in Neuroscience (12-10-2007)
    “…Abstract Bedridden patients who receive good physical rehabilitation are able to exhibit clinical improvement. Accumulating evidence demonstrates that exercise…”
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    Microsurgery for vestibular schwannoma after gamma knife radiosurgery by Shuto, T., Inomori, S., Matsunaga, S., Fujino, H.

    Published in Acta neurochirurgica (01-03-2008)
    “…Summary Background. We evaluated the clinical characteristics of microsurgery for vestibular schwannoma (VS) after failed gamma knife radiosurgery (GKS)…”
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    Protective effects of exercise preconditioning on hindlimb unloading-induced atrophy of rat soleus muscle by Fujino, H., Ishihara, A., Murakami, S., Yasuhara, T., Kondo, H., Mohri, S., Takeda, I., Roy, R. R.

    Published in Acta Physiologica (01-09-2009)
    “…Aim:  A chronic decrease in the activation and loading levels of skeletal muscles as occurs with hindlimb unloading (HU) results in a number of detrimental…”
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    The balance of VEGF-C and VEGFR-3 mRNA is a predictor of lymph node metastasis in non-small cell lung cancer by TAKIZAWA, H, KONDO, K, FUJINO, H, KENZAKI, K, MIYOSHI, T, SAKIYAMA, S, TANGOKU, A

    Published in British journal of cancer (03-07-2006)
    “…A positive association between vascular endothelial growth factor-C (VEGF-C) expression and lymph node metastasis has been reported in several cancers…”
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    Betulinic acid augments the inhibitory effects of vincristine on growth and lung metastasis of B16F10 melanoma cells in mice by SAWADA, N, KATAOKA, K, KONDO, K, ARIMOCHI, H, FUJINO, H, TAKAHASHI, Y, MIYOSHI, T, KUWAHARA, T, MONDEN, Y, OHNISHI, Y

    Published in British journal of cancer (19-04-2004)
    “…We examined the antitumour effect of a combination of betulinic acid (BA) and vincristine (VCR) on murine melanoma B16F10 cells in vitro and in vivo. Betulinic…”
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    Metabolic properties of the acid and lactone forms of HMG-CoA reductase inhibitors by Fujino, H., Saito, T., Tsunenari, Y., Kojima, J., Sakaeda, T.

    Published in Xenobiotica (01-11-2004)
    “…1. To gain a better understanding of the metabolic properties between the open acid and lactone form of HMG-CoA reductase inhibitors (statins), the paper…”
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    Switching of Lasing Circular Polarizations in a (110)-VCSEL by Ikeda, K., Fujimoto, T., Fujino, H., Katayama, T., Koh, S., Kawaguchi, H.

    Published in IEEE photonics technology letters (15-09-2009)
    “…We discuss our demonstration of gigahertz switching of lasing circular polarizations in a (110) GaAs-based vertical-cavity surface-emitting laser (VCSEL)…”
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    Gamma knife radiosurgery for intracranial haemangioblastomas by Matsunaga, S, Shuto, T, Inomori, S, Fujino, H, Yamamoto, I

    Published in Acta neurochirurgica (01-10-2007)
    “…The results of gamma knife radiosurgery for haemangioblastomas were retrospectively studied to assess the efficacy for tumour growth control and clarify the…”
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    Different expression patterns of hepatic cytochrome P450 s during anaphylactic or lipopolysaccharide-induced inflammation by Moriya, N, Kataoka, H, Fujino, H, Nishikawa, J, Kugawa, F

    Published in Pharmazie (01-02-2014)
    “…Certain physiological states and diseases can alter the expression and activity of cytochrome P450 s (CYPs), which have the potential to cause unexpected…”
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    Preventive effect of nucleoprotein on hindlimb unloading-induced capillary regression in rat soleus muscle by Kanazawa, Y, Maekawa, K, Okumura, Y, Fujita, N, Fujino, H

    Published in Biotechnic & histochemistry (01-04-2014)
    “…We investigated the preventive effects of nucleoprotein on capillary regression and mitochondrial dysfunction induced by unloading in the soleus muscle of…”
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    The key role of stem cell factor KIT signaling in the proliferation of blast cells from Down syndrome-related leukemia by Toki, T, Kanezaki, R, Adachi, S, Fujino, H, Xu, G, Sato, T, Suzuki, K, Tauchi, H, Endo, M, Ito, E

    Published in Leukemia (01-01-2009)
    “…Transient leukemia (TL) has been observed in approximately 10% of newborn infants with Down syndrome (DS). Although treatment with cytarabine is effective in…”
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    Metabolic fate of pitavastatin, a new inhibitor of HMG-CoA reductase: human UDP-glucuronosyltransferase enzymes involved in lactonization by Fujino, H., Yamada, I., Shimada, S., Yoneda, M., Kojima, J.

    Published in Xenobiotica (2003)
    “…1. Pitavastatin is a potent competitive inhibitor of HMG-CoA reductase little metabolized in hepatic microsomes. Pitavastatin lactone, which can be converted…”
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    Efficacy of gamma knife surgery for control of peritumoral oedema associated with metastatic brain tumours by Shuto, T, Matsunaga, S, Inomori, S, Fujino, H

    “…Objectives: To evaluate the efficacy of gamma knife surgery (GKS) for the control of peritumoral oedema associated with metastatic brain tumours. Methods: A…”
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    CYP2C76-mediated species difference in drug metabolism: A comparison of pitavastatin metabolism between monkeys and humans by Uno, Y., Kumano, T., Kito, G., Nagata, R., Kamataki, T., Fujino, H.

    Published in Xenobiotica (01-01-2007)
    “…The monkey is often used to predict metabolism of drugs in humans since it generally shows a metabolic pattern similar to humans. However, metabolic profiles…”
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