Search Results - "FUJIMOTO, Kazunori"

Determination of key residues in MRGPRX2 to enhance pseudo-allergic reactions induced by fluoroquinolones by Hamamura-Yasuno, Eri, Matsushita, Junya, Sato, Seiji, Shimada, Takashi, Tsuchiya, Yoshimi, Fujimoto, Kazunori, Mori, Kazuhiko

“…MAS-related G protein-coupled receptor X2 (MRGPRX2), expressed in human mast cells, is associated with drug-induced pseudo-allergic reactions. Dogs are highly…”
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Effective in vitro evaluation of the risk of histamine release related to valemetostat tosylate using MRGPRX2-expressing cells by Hamamura-Yasuno, Eri, Kinoshita, Junzo, Goto, Koichi, Fujimoto, Kazunori, Pignatello, Michael, Tsuchiya, Yoshimi, Mori, Kazuhiko

“…Mas-related G-protein-coupled receptor X2 (MRGPRX2), expressed on mast cells, is associated with drug-induced pseudo-allergic reactions. Although it is well…”
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Effects of the valence and argument substantiveness of others' comments on viewers' validation of and attitudes toward pseudo-scientific claims by Inuzuka, Miwa, Tanaka, Yuko, Fujimoto, Kazunori

“…This study examines how the valence and argument of comments affect viewers' attitudes toward and validation of a pseudo-scientific claim. We developed and…”
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Biochemical profiles of rat primary cultured hepatocytes following treatment with rotenone, FCCP, or (+)-usnic acid by Fujimoto, Kazunori, Kishino, Hiroyuki, Hashimoto, Kazuyuki, Watanabe, Kyoko, Yamoto, Takashi, Mori, Kazuhiko

“…The metabolomic profiles of rat primary hepatocytes following treatment with rotenone, FCCP, or (+)-usnic acid were determined using liquid chromatography-mass…”
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Angiopoietin-Like Protein3 Regulates Plasma HDL Cholesterol Through Suppression of Endothelial Lipase by Shimamura, Mitsuru, Matsuda, Morihiro, Yasumo, Hiroaki, Okazaki, Mitsuyo, Fujimoto, Kazunori, Kono, Keita, Shimizugawa, Tetsuya, Ando, Yosuke, Koishi, Ryuta, Kohama, Takafumi, Sakai, Naohiko, Kotani, Kazuaki, Komuro, Ryutaro, Ishida, Tatsuo, Hirata, Kenichi, Yamashita, Shizuya, Furukawa, Hidehiko, Shimomura, Iichiro

“…OBJECTIVES—A low level of high-density lipoprotein (HDL) in plasma has been recognized as an aspect of metabolic syndrome and as a crucial risk factor of…”
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Isoniazid-induced cell death is precipitated by underlying mitochondrial complex I dysfunction in mouse hepatocytes by Lee, Kang Kwang, Fujimoto, Kazunori, Zhang, Carmen, Schwall, Christine T, Alder, Nathan N, Pinkert, Carl A, Krueger, Winfried, Rasmussen, Theodore, Boelsterli, Urs A

“…Isoniazid (INH) is an antituberculosis drug that has been associated with idiosyncratic liver injury in susceptible patients. The underlying mechanisms are…”
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KEY RESIDUES IN DRUG-INDUCED IgE-INDEPENDENT PSEUDO-ALLERGIC REACTIONS VIA MAS-RELATED G-PROTEIN COUPLED RECEPTOR X2 by Hamamura-Yasuno, Eri, Shimada, Takashi, Fujimoto, Kazunori, Mori, Kazuhiko

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Identification of genes related to heart failure using global gene expression profiling of human failing myocardium by Min, Kyung-Duk, Asakura, Masanori, Liao, Yulin, Nakamaru, Kenji, Okazaki, Hidetoshi, Takahashi, Tomoko, Fujimoto, Kazunori, Ito, Shin, Takahashi, Ayako, Asanuma, Hiroshi, Yamazaki, Satoru, Minamino, Tetsuo, Sanada, Shoji, Seguchi, Osamu, Nakano, Atsushi, Ando, Yosuke, Otsuka, Toshiaki, Furukawa, Hidehiko, Isomura, Tadashi, Takashima, Seiji, Mochizuki, Naoki, Kitakaze, Masafumi

“…Although various management methods have been developed for heart failure, it is necessary to investigate the diagnostic or therapeutic targets of heart…”
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Analysis of Prostate Deformation during a Course of Radiation Therapy for Prostate Cancer by Nakazawa, Takuya, Tateoka, Kunihiko, Saito, Yuichi, Abe, Tadanori, Yano, Masaki, Yaegashi, Yuji, Narimatsu, Hirokazu, Fujimoto, Kazunori, Nakata, Akihiro, Nakata, Kensei, Someya, Masanori, Hori, Masakazu, Hareyama, Masato, Sakata, Koichi

“…Accurate analysis of the correlation between deformation of the prostate and displacement of its center of gravity (CoG) is important for efficient radiation…”
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Angptl3-null Mice Show Low Plasma Lipid Concentrations by Enhanced Lipoprotein Lipase Activity by FUJIMOTO, Kazunori, KOISHI, Ryuta, SHIMIZUGAWA, Tetsuya, ANDO, Yosuke

“…Angiopoietin-like 3 (ANGPTL3) is a secreted protein with both angiogenesis and lipid metabolism functions. We generated knockout mice that failed to express…”
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In vitro cytotoxicity assay to evaluate the toxicity of an electrophilic reactive metabolite using glutathione-depleted rat primary cultured hepatocytes by Fujimoto, Kazunori, Kishino, Hiroyuki, Yamoto, Takashi, Manabe, Sunao, Sanbuissho, Atsushi

“…Glutathione plays an important role as not only a scavenger of reactive oxygen species but also in the conjugation or detoxification of electrophilic reactive…”
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Evaluation of hepatic glutathione transferase Mu 1 and Theta 1 activities in humans and mice using genotype information by Arakawa, Shingo, Fujimoto, Kazunori, Kato, Ayako, Endo, Seiko, Fukahori, Aiko, Shinagawa, Akira, Fischer, Thomas, Mueller, Juergen, Takasaki, Wataru

“…We investigated the impact of glutathione transferases Mu 1 (GSTM1)- and glutathione transferase Theta 1 (GSTT1)-null genotypes on hepatic GST activities in…”
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Resistance to acetaminophen-induced hepatotoxicity in glutathione S-transferase Mu 1-null mice by Arakawa, Shingo, Maejima, Takanori, Fujimoto, Kazunori, Yamaguchi, Takashi, Yagi, Masae, Sugiura, Tomomi, Atsumi, Ryo, Yamazoe, Yasushi

“…We investigated the role of glutathione S-transferases Mu 1 (GSTM1) in acetaminophen (APAP)-induced hepatotoxicity using Gstm1-null mice. A single oral…”
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Analysis of post-exposure density growth in radiochromic film with respect to the radiation dose by Shima, Katsumi, Tateoka, Kunihiko, Saitoh, Yuichi, Suzuki, Junji, Yaegashi, Yuji, Fujimoto, Kazunori, Nakazawa, Takuya, Nakata, Akihiro, Abe, Tadanori, Imai, Sho, Sakata, Kouichi, Hareyama, Masato

“…The post-exposure density growth (PEDG) is one of the characteristics of radiochromic film (RCF). In film dosimetry using RCF and a flatbed scanner, pixel…”
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The generation and behavioral analysis of ceramide kinase-null mice, indicating a function in cerebellar Purkinje cells by Mitsutake, Susumu, Yokose, Urara, Kato, Mariko, Matsuoka, Ichiro, Yoo, Jae-Myung, Kim, Tack-Joong, Yoo, Hwan-Soo, Fujimoto, Kazunori, Ando, Yasuke, Sugiura, Masako, Kohama, Takafumi, Igarashi, Yasuyuki

“…The discovery of ceramide kinase (CerK), which phosphorylates ceramide (Cer) to ceramide 1-phisphate (C1P), established a new pathway for Cer metabolism. Among…”
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Generation and Functional Characterization of Mice with a Disrupted Glutathione S-Transferase, Theta 1 Gene by FUJIMOTO, Kazunori, ARAKAWA, Shingo, WATANABE, Toshiyuki, YASUMO, Hiroaki, ANDO, Yosuke, TAKASAKI, Wataru, MANABE, Sunao, YAMOTO, Takashi, ODA, Sen-Ichi

“…Glutathione S -transferase (GST) theta 1 (GSTT1) has been regarded as one of the key enzymes involved in phase II reactions because of its unique substrate…”
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Uncertainty in patient set-up margin analysis in radiation therapy by Suzuki, Junji, Tateoka, Kunihiko, Shima, Katsumi, Yaegashi, Yuji, Fujimoto, Kazunori, Saitoh, Yuichi, Nakata, Akihiro, Abe, Tadanori, Nakazawa, Takuya, Sakata, Kouichi, Hareyama, Masato

“…We investigated the uncertainty in patient set-up margin analysis with a small dataset consisting of a limited number of clinical cases over a short time…”
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Characterization of Phenotypes in Gstm1-null Mice by Cytosolic and in Vivo Metabolic Studies Using 1,2-Dichloro-4-Nitrobenzene by FUJIMOTO, Kazunori, ARAKAWA, Shingo, MANABE, Sunao, YAMOTO, Takashi, SHIBAYA, Yukari, MIIDA, Hiroaki, ANDO, Yosuke, YASUMO, Hiroaki, HARA, Ayako, UCHIYAMA, Minoru, IWABUCHI, Haruo, TAKASAKI, Wataru

“…Glutathione S -transferase Mu 1 (GSTM1) has been regarded as one of the key enzymes involved in phase II reactions in the liver, because of its high expression…”
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Selective Intervention Strategy Based on Content Perception Model Against Fake News Sharing by Fujimoto, Kazunori, Tanaka, Yuko, Inuzuka, Miwa

“…This paper presents an intervention strategy, called a selective intervention, designed using a content perception model to analyze intervention effects at the…”
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Premature deindustrialization, inter-sectoral employment shifts, and accelerated servicization by Fujimoto, Kazunori, Whittaker, D. Hugh

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