CS-807 IN THE FIELD OF SURGERY
Serum and bile levels and clinical effects of the new oral cephalosporin CS-807 were determined, and the following results were obtained: 1) When CS-807 was postoperative by at an oral dose of 200mg after meals, serum levels reached a peak value of 1.87μg/ml 4 hours after administration. At the same...
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| Published in: | CHEMOTHERAPY Vol. 36; no. Supplement1; pp. 677 - 684 |
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| Main Authors: | , , , , , , , , |
| Format: | Journal Article |
| Language: | English Japanese |
| Published: |
Japanese Society of Chemotherapy
1988
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| Online Access: | Get full text |
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| Summary: | Serum and bile levels and clinical effects of the new oral cephalosporin CS-807 were determined, and the following results were obtained: 1) When CS-807 was postoperative by at an oral dose of 200mg after meals, serum levels reached a peak value of 1.87μg/ml 4 hours after administration. At the same dose in patients undergoing PTCD, bile levels showed a peak of 1.83μg/ml 6-7 hours after administration. 2) Clinical effects of CS-807 in 39 cases with soft tissue or skin infections was excellent in 8, good in 19, fair 9, and poor in 3; the overall effective rate being 69.2%. 3) Although one patient each complained of urticaria and abdominal discomfort as side-effects these symptoms were transitory, and there was no clear causal relation with the drug. No abnormal laboratory findings were found. |
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| ISSN: | 0009-3165 1884-5894 |
| DOI: | 10.11250/chemotherapy1953.36.Supplement1_677 |