Search Results - "FUESSEL, SUSANNE"

Prognostic potential of standard laboratory parameters in patients with metastatic renal cell cancer receiving first-line immunotherapy by Buerk, Bjoern Thorben, Kusiek, Cathrin, Schüttke, Vayda, Sondermann, Marcus, Yakac, Abdulbaki, Abbate, Elena, Fuessel, Susanne, Thomas, Christian, Erdmann, Kati

“…Through their involvement in cancer metabolism, alanine aminotransferase (ALAT), aspartate aminotransferase (ASAT), γ-glutamyltransferase (GGT) and lactate…”
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Evaluation of TERT promoter mutations in urinary cell-free DNA and sediment DNA for detection of bladder cancer by Stasik, Sebastian, Salomo, Karsten, Heberling, Ulrike, Froehner, Michael, Sommer, Ulrich, Baretton, Gustavo B., Ehninger, Gerhard, Wirth, Manfred P., Thiede, Christian, Fuessel, Susanne

“…Cell-free DNA (cfDNA) is proposed to be a valuable source of biomarkers in liquid biopsies for various diseases as it is supposed to partially originate from…”
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Comprehensive Evaluation of Multiple Approaches Targeting ABCB1 to Resensitize Docetaxel-Resistant Prostate Cancer Cell Lines by Linke, Dinah, Donix, Lukas, Peitzsch, Claudia, Erb, Holger H H, Dubrovska, Anna, Pfeifer, Manuel, Thomas, Christian, Fuessel, Susanne, Erdmann, Kati

“…Docetaxel (DTX) is a mainstay in the treatment of metastatic prostate cancer. Failure of DTX therapy is often associated with multidrug resistance caused by…”
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Acquired resistance to irradiation or docetaxel is not associated with cross-resistance to cisplatin in prostate cancer cell lines by Donix, Lukas, Erb, Holger H. H., Peitzsch, Claudia, Dubrovska, Anna, Pfeifer, Manuel, Thomas, Christian, Fuessel, Susanne, Erdmann, Kati

“…Purpose Platinum chemotherapy can be considered to treat metastatic castration-resistant prostate cancer (mCRPC) with features of neuroendocrine…”
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Assessment of STAT5 as a potential therapy target in enzalutamide-resistant prostate cancer by Erb, Holger H H, Bodenbender, Julia, Handle, Florian, Diehl, Tamara, Donix, Lukas, Tsaur, Igor, Gleave, Martin, Haferkamp, Axel, Huber, Johannes, Fuessel, Susanne, Juengel, Eva, Culig, Zoran, Thomas, Christian

“…Despite enzalutamide's efficacy in delaying the progression of metastatic castration-resistant prostate cancer (CRPC), resistance to this anti-androgen…”
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Urinary MicroRNAs as Potential Markers for Non-Invasive Diagnosis of Bladder Cancer by Erdmann, Kati, Salomo, Karsten, Klimova, Anna, Heberling, Ulrike, Lohse-Fischer, Andrea, Fuehrer, Romy, Thomas, Christian, Roeder, Ingo, Froehner, Michael, Wirth, Manfred P, Fuessel, Susanne

“…Currently, voided urine cytology (VUC) serves as the gold standard for the detection of bladder cancer (BCa) in urine. Despite its high specificity, VUC has…”
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Inhibition of Human Urokinase-Type Plasminogen Activator (uPA) Enzyme Activity and Receptor Binding by DNA Aptamers as Potential Therapeutics through Binding to the Different Forms of uPA by Dreymann, Nico, Wuensche, Julia, Sabrowski, Wiebke, Moeller, Anja, Czepluch, Denise, Vu Van, Dana, Fuessel, Susanne, Menger, Marcus M

“…Urokinase-type plasminogen activator is widely discussed as a marker for cancer prognosis and diagnosis and as a target for cancer therapies. Together with its…”
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Emerging frontiers in androgen receptor research for prostate Cancer: insights from the 2nd international androgen receptor Symposium by Israel, Justus Simon, Marcelin, Laura-Maria, Thomas, Christian, Szczyrbová, Eva, Fuessel, Susanne, Puhr, Martin, Linxweiler, Johannes, Yalala, Shivani, Zwart, Wilbert T, Baniahmad, Aria, van Goubergen, Jasper, Itkonen, Harri M, Sharp, Adam, O'Neill, Edward, Pretze, Marc, Miederer, Matthias, Erb, Holger H H

“…Continued exploration of the androgen receptor (AR) is crucial, as it plays pivotal roles in diverse diseases such as prostate cancer (PCa), serving as a…”
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Analyses of potential predictive markers and survival data for a response to sunitinib in patients with metastatic renal cell carcinoma by Dornbusch, Juana, Zacharis, Aristeidis, Meinhardt, Matthias, Erdmann, Kati, Wolff, Ingmar, Froehner, Michael, Wirth, Manfred P, Zastrow, Stefan, Fuessel, Susanne

“…Patients with metastatic clear cell renal cell carcinoma (ccRCC) are frequently treated with tyrosine kinase inhibitors (TKI) such as sunitinib. It inhibits…”
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Linking NRP2 With EMT and Chemoradioresistance in Bladder Cancer by Schulz, Alexander, Gorodetska, Ielizaveta, Behrendt, Rayk, Fuessel, Susanne, Erdmann, Kati, Foerster, Sarah, Datta, Kaustubh, Mayr, Thomas, Dubrovska, Anna, Muders, Michael H

“…Neuropilin-2 (NRP2) is a prognostic indicator for reduced survival in bladder cancer (BCa) patients. Together with its major ligand, vascular endothelial…”
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WNT5A Has Anti‐Prostate Cancer Effects In Vitro and Reduces Tumor Growth in the Skeleton In Vivo by Thiele, Stefanie, Göbel, Andy, Rachner, Tilman D, Fuessel, Susanne, Froehner, Michael, Muders, Michael H, Baretton, Gustavo B, Bernhardt, Ricardo, Jakob, Franz, Glüer, Claus C, Bornhäuser, Martin, Rauner, Martina, Hofbauer, Lorenz C

“…ABSTRACT Prostate cancer is the most frequent malignancy in men, and a major cause of prostate cancer–related death is attributable to bone metastases. WNT5A…”
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Carbon nanomaterials sensitize prostate cancer cells to docetaxel and mitomycin C via induction of apoptosis and inhibition of proliferation by Erdmann, Kati, Ringel, Jessica, Hampel, Silke, Wirth, Manfred P, Fuessel, Susanne

“…We have previously shown that carbon nanofibers (CNFs) and carbon nanotubes (CNTs) can sensitize prostate cancer (PCa) cells to platinum-based…”
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An orthotopic xenograft model for high-risk non-muscle invasive bladder cancer in mice: influence of mouse strain, tumor cell count, dwell time and bladder pretreatment by Huebner, Doreen, Rieger, Christiane, Bergmann, Ralf, Ullrich, Martin, Meister, Sebastian, Toma, Marieta, Wiedemuth, Ralf, Temme, Achim, Novotny, Vladimir, Wirth, Manfred P, Bachmann, Michael, Pietzsch, Jens, Fuessel, Susanne

“…Novel theranostic options for high-risk non-muscle invasive bladder cancer are urgently needed. This requires a thorough evaluation of experimental approaches…”
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Role of WNT5A receptors FZD5 and RYK in prostate cancer cells by Thiele, Stefanie, Zimmer, Ariane, Göbel, Andy, Rachner, Tilman D, Rother, Sandra, Fuessel, Susanne, Froehner, Michael, Wirth, Manfred P, Muders, Michael H, Baretton, Gustavo B, Jakob, Franz, Rauner, Martina, Hofbauer, Lorenz C

“…Prostate cancer is the most common malignancy in men and has a high propensity to metastasize to bone. WNT5A has recently been implicated in the progression of…”
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Evaluation of MicroRNAs as Non-Invasive Diagnostic Markers in Urinary Cells from Patients with Suspected Prostate Cancer by Borkowetz, Angelika, Lohse-Fischer, Andrea, Scholze, Jana, Lotzkat, Ulrike, Thomas, Christian, Wirth, Manfred P, Fuessel, Susanne, Erdmann, Kati

“…Currently used tumor markers for early diagnosis of prostate cancer (PCa) are often lacking sufficient specificity and sensitivity. Therefore, the diagnostic…”
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Identification and Validation of Potential New Biomarkers for Prostate Cancer Diagnosis and Prognosis Using 2D-DIGE and MS by Diehl, Hanna C., Borchers, Christoph H., Heidenreich, Axel, Meyer, Helmut E., Knuechel, Ruth, Henkel, Corinna, Beine, Birte, Gostek, Sonja, Braunschweig, Till, Kristiansen, Glen, Füssel, Susanne, Pfister, David, Gaisa, Nadine T., Geisler, Cordelia, Jackson, Angela M.

“…This study was designed to identify and validate potential new biomarkers for prostate cancer and to distinguish patients with and without biochemical relapse…”
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Lack of ephrin receptor A1 is a favorable independent prognostic factor in clear cell renal cell carcinoma by Toma, Marieta I, Erdmann, Kati, Diezel, Michael, Meinhardt, Matthias, Zastrow, Stefan, Fuessel, Susanne, Wirth, Manfred P, Baretton, Gustavo B

“…The EPH receptor tyrosine kinases and their cell-bound ligands, the ephrins, have been shown to be associated with cancer development and progression. In this…”
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Chemosensitizing effects of carbon-based nanomaterials in cancer cells: enhanced apoptosis and inhibition of proliferation as underlying mechanisms by Erdmann, Kati, Ringel, Jessica, Hampel, Silke, Rieger, Christiane, Huebner, Doreen, Wirth, Manfred P, Fuessel, Susanne

“…Recent studies have shown that carbon nanomaterials such as carbon nanofibres (CNFs) and multi-walled carbon nanotubes (CNTs) can exert antitumor activities…”
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Detection of Circulating Tumor Cells in Peripheral Blood of Patients with Renal Cell Carcinoma Correlates with Prognosis by BLUEMKE, Karen, BILKENROTH, Udo, MEYE, Axel, FUESSEL, Susanne, LAUTENSCHLAEGER, Christine, GOEBEL, Steffen, MELCHIOR, Andres, HEYNEMANN, Hans, FORNARA, Paolo, TAUBERT, Helge

“…Purpose: The aim of this study was to evaluate the clinical relevance of the presence of disseminated tumor cells in peripheral blood (so-called circulating…”
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Expression profile of WNT molecules in prostate cancer and its regulation by aminobisphosphonates by Thiele, Sylvia, Rauner, Martina, Goettsch, Claudia, Rachner, Tilman D., Benad, Peggy, Fuessel, Susanne, Erdmann, Kati, Hamann, Christine, Baretton, Gustavo B., Wirth, Manfred P., Jakob, Franz, Hofbauer, Lorenz C.

“…Skeletal metastases represent a frequent complication in patients with advanced prostate cancer (PCa) and often require bisphosphonate treatment to limit…”
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