Search Results - "FRYXELL, K. J"

Synergistic Effects of Genetic Variation in Nicotinic and Muscarinic Receptors on Visual Attention but Not Working Memory by Greenwood, P. M., Lin, M.-K., Sundararajan, R., Fryxell, K. J., Parasuraman, R., Iversen, L. L.

“…It is widely appreciated that neurotransmission systems interact in their effects on human cognition, but those interactions have been little studied. We used…”
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The coevolution of gene family trees by Fryxell, Karl J.

“…Gene duplication mutants arise spontaneously at a high rate in bacteria, bacteriophages, insects and mammalian cells, and are generally viable. Thus, the…”
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Cytosine deamination plays a primary role in the evolution of mammalian isochores by Fryxell, K J, Zuckerkandl, E

“…DNA melting is rate-limiting for cytosine deamination, from which we infer that the rate of cytosine deamination should decline twofold for each 10% increase…”
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An opsin gene that is expressed only in the R7 photoreceptor cell of Drosophila by Fryxell, K.J., Meyerowitz, E.M.

“…We have used two techniques to isolate and characterize eye‐specific genes from Drosophila melanogaster. First, we identified genes whose expression is limited…”
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The evolution of rhodopsins and neurotransmitter receptors by FRYXELL, K. J, MEYEROWITZ, E. M

“…Rhodopsins share a limited number of amino acid identities with a variety of other integral membrane proteins. Most of these proteins have seven putative…”
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Pantropic retroviral vectors mediate somatic cell transformation and expression of foreign genes in dipteran insects by Jordan, T. V., Shike, H., Boulo, V., Cedeno, V., Fang, Q., Davis, B. S., Jacobs‐Lorena, M., Higgs, S., Fryxell1, K. J., Burns, J. C.

“…The control of insects that transmit disease and damage crops has become increasingly difficult. The ability to genetically engineer insects would facilitate…”
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A rapid and efficient method of subcloning into transformation vectors by Fryxell, K J, Kumar, J P, Johnson, J L

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An animal model for the molecular genetics of CADASIL. (Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy) by Fryxell, K J, Soderlund, M, Jordan, T V

“…CADASIL (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy) is an inherited condition that causes repeated small-scale…”
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Studies on cultured Schwann cells: the induction of myelin synthesis, and the control of their proliferation by a new growth factor by Brockes, J P, Fryxell, K J, Lemke, G E

“…We have recently described the use of immunological methods to identify and purify rat Schwann cells. In dissociated cultures of neonatal sciatic nerve, all of…”
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The evolutionary divergence of neurotransmitter receptors and second-messenger pathways by Fryxell, K J

“…Members of the superfamily of G-protein-coupled neurotransmitter receptors have a conserved secondary structure, a moderate and reasonably steady rate of…”
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Both a Nicotinic Single Nucleotide Polymorphism (SNP) and a Noradrenergic SNP Modulate Working Memory Performance when Attention Is Manipulated by Greenwood, Pamela M, Sundararajan, Ramya, Lin, Ming-Kuan, Kumar, Reshma, Fryxell, Karl J, Parasuraman, Raja

“…We investigated the relation between the two systems of visuospatial attention and working memory by examining the effect of normal variation in cholinergic…”
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CpG mutation rates in the human genome are highly dependent on local GC content by Fryxell, Karl J, Moon, Won-Jong

“…CpG dinucleotides mutate at a high rate because cytosine is vulnerable to deamination, cytosines in CpG dinucleotides are often methylated, and deamination of…”
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Nicotine causes age-dependent changes in gene expression in the adolescent female rat brain by Polesskaya, Oksana O, Fryxell, Karl J, Merchant, Amita D, Locklear, Laura L, Ker, Ko-Fei, McDonald, Craig G, Eppolito, Amy K, Smith, Laura N, Wheeler, Tracey L, Smith, Robert F

“…Abstract Humans often start smoking during adolescence. Recent results suggest that rodents may also be particularly vulnerable to nicotine dependence during…”
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Synthesis of sulfatide by cultured rat Schwann cells by Fryxell, K J

“…The 35S sulfolipids synthesized by purified cultures of rat Schwann cells, fibroblasts, and a rat cell line (RN2) were studied. Schwann cell 35S sulfolipids…”
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Characterization of the radiation-sensitive stage in the development of the compound eye of Drosophila by Fryxell, K J, Kumar, J P

“…The development of the compound eye of Drosophila is particularly sensitive to irradiation during the third larval instar. Moreover, the anterioposterior…”
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Development and applications of a solid-phase radioimmunoassay for the PO protein of peripheral myelin by Fryxell, K J, Balzer, Jr, D R, Brockes, J P

“…This is the first report of a quantitative radioimmunoassay for PO. The assay uses antigen-coated plastic microwells, with antibody binding detected by…”
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Genetic mosaic analysis of the equatorial-less mutation in Drosophila melanogaster by Fryxell, K J, Wood, C P

“…eql (equatorial-less) is a recessive lethal mutation on the second chromosome of Drosophila melanogaster. J. Campos-Ortega found that eql clones in somatic…”
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Effective antiprotease-antibiotic treatment of experimental anthrax by Popov, Serguei G, Popova, Taissia G, Hopkins, Svetlana, Weinstein, Raymond S, MacAfee, Rebecca, Fryxell, Karl J, Chandhoke, Vikas, Bailey, Charles, Alibek, Ken

“…Inhalation anthrax is characterized by a systemic spread of the challenge agent, Bacillus anthracis. It causes severe damage, including multiple hemorrhagic…”
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