Search Results - "FRONTELO, Pilar"

Novel role for EKLF in megakaryocyte lineage commitment by Frontelo, Pilar, Manwani, Deepa, Galdass, Mariann, Karsunky, Holger, Lohmann, Felix, Gallagher, Patrick G., Bieker, James J.

“…Megakaryocytes and erythroid cells are thought to derive from a common progenitor during hematopoietic differentiation. Although a number of transcriptional…”
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Blockade of Smad4 in transformed keratinocytes containing a Ras oncogene leads to hyperactivation of the Ras-dependent Erk signalling pathway associated with progression to undifferentiated carcinomas by IGLESIAS, M, FRONTELO, P, GAMALLO, C, QUINTANILLA, M

“…Smad4 functions as a transcription factor in TGF-beta signalling. We have investigated the role of Smad4 in the TGF-beta1 cell responses of transformed PDV…”
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Suv39h histone methyltransferases interact with Smads and cooperate in BMP-induced repression by FRONTELO, Pilar, LEADER, Jennifer E, YOO, Naomi, POTOCKI, Alex C, CRAWFORD, Michelle, KULIK, Magdalena, LECHLEIDER, Robert J

“…Smad proteins transduce signals from transforming growth factor-beta (TGF-beta) superfamily ligands to regulate the expression of target genes. In order to…”
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A retrospective pooled analysis of trabectedin safety in 1,132 patients with solid tumors treated in phase II clinical trials by Le Cesne, Axel, Yovine, Alejandro, Blay, Jean-Yves, Delaloge, Suzette, Maki, Robert G., Misset, Jean-Louis, Frontelo, Pilar, Nieto, Antonio, Jiao, Juhui James, Demetri, George D.

“…Summary Purpose To summarize the safety experience obtained from phase II clinical trials conducted with trabectedin as single-agent therapy in patients with…”
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Involvement of the Ras/MAPK Signaling Pathway in the Modulation of Urokinase Production and Cellular Invasiveness by Transforming Growth Factor-β1 in Transformed Keratinocytes by Santibáñez, Juan F., Iglesias, Maite, Frontelo, Pilar, Martínez, Jorge, Quintanilla, Miguel

“…Transformed PDV keratinocytes respond to TGF-β1 by stimulating cell motility and invasiveness concomitantly to enhancement of the urokinase-type plasminogen…”
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Novel role for EKLF in megakaryocyte lineage commitment. Commentary by BLOBEL, Gerd A, FRONTELO, Pilar, MANWANI, Deepa, GALDASS, Mariann, KARSUNKY, Holger, LOHMANN, Felix, GALLAGHER, Patrick G, BIEKER, James J

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Urokinase expression and binding activity associated with the transforming growth factor β1-induced migratory and invasive phenotype of mouse epidermal keratinocytes by Santibáñez, Juan F., Frontelo, Pilar, Iglesias, Maite, Martínez, Jorge, Quintanilla, Miguel

“…Transforming growth factor β1(TGF‐β1) is a stimulator of malignant progression in mouse skin carcinogenesis. TGF‐β1 exerts a differential effect on cultured…”
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Transforming Growth Factor β1Induces Squamous Carcinoma Cell Variants with Increased Metastatic Abilities and a Disorganized Cytoskeleton by Frontelo, Pilar, González-Garrigues, Milagro, Vilaró, Senén, Gamallo, Carlos, Fabra, Angels, Quintanilla, Miguel

“…Previous studies indicated that mouse transformed keratinocytes undergo an epithelial–fibroblastic conversion when cultured in the presence of TGF-β1. This…”
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Urokinase expression and binding activity associated with the transforming growth factor ?1-induced migratory and invasive phenotype of mouse epidermal keratinocytes by Santib ez, Juan F., Frontelo, Pilar, Iglesias, Maite, Mart nez, Jorge, Quintanilla, Miguel

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Novel Role for EKLF in Megakaryocyte-Erythroid Differential Lineage Commitment by Frontelo, Maria Pilar, Manwani, Deepa, Galdass, Mariann, Karsunky, Holger, Gallagher, Patrick G., Bieker, James J.

“…Megakaryocytes and erythroid cells are thought to derive from a common progenitor. Although a number of transcriptional regulators are important for this…”
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