Search Results - "FRITSCH, Samuel"
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RIP140 inhibits glycolysis-dependent proliferation of breast cancer cells by regulating GLUT3 expression through transcriptional crosstalk between hypoxia induced factor and p53
Published in Cellular and molecular life sciences : CMLS (01-05-2022)“…Glycolysis is essential to support cancer cell proliferation, even in the presence of oxygen. The transcriptional co-regulator RIP140 represses the activity of…”
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The Transcriptional Coregulator RIP140 Represses E2F1 Activity and Discriminates Breast Cancer Subtypes
Published in Clinical cancer research (01-06-2010)“…Receptor-interacting protein of 140 kDa (RIP140) is a transcriptional cofactor for nuclear receptors involved in reproduction and energy homeostasis. Our aim…”
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Type 1 parathyroid hormone receptor expression level modulates renal tone and plasma renin activity in spontaneously hypertensive rat
Published in Journal of the American Society of Nephrology (01-03-2002)“…These studies examine whether PTHrP(1-36), a vasodilator, modulates BP and renal vascular resistance (RVR) in spontaneously hypertensive rat (SHR). Within the…”
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The E3 Ubiquitin Ligase Thyroid Hormone Receptor-interacting Protein 12 Targets Pancreas Transcription Factor 1a for Proteasomal Degradation
Published in The Journal of biological chemistry (19-12-2014)“…Pancreas transcription factor 1a (PTF1a) plays a crucial role in the early development of the pancreas and in the maintenance of the acinar cell phenotype…”
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Abstract 4970: Complex regulation of RIP140 gene expression by E2F transcription factors
Published in Cancer research (Chicago, Ill.) (15-04-2010)“…Abstract We recently showed that RIP140 (Receptor Interacting protein of 140 kDa), a regulator of nuclear receptor activity, was involved in the control of…”
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Cognitive impairments in adult mice with constitutive inactivation of RIP140 gene expression: Behavioral phenotype of RIP140-/- mice
Published in Genes, brain and behavior (01-02-2012)“…Receptor-interacting protein 140 (RIP140) is a negative transcriptional coregulator of nuclear receptors such as estrogen, retinoic acid or glucocorticoid…”
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Intravenous delivery of PTH/PTHrP type 1 receptor cDNA to rats decreases heart rate, blood pressure, renal tone, renin angiotensin system, and stress-induced cardiovascular responses
Published in Journal of the American Society of Nephrology (01-10-2004)“…While parathyroid hormone type 1 receptor (PTH1R)-mediated vasodilatory, cardiac stimulatory, and renin-activating effects of exogenous PTH/PTH-related protein…”
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Transcript Expression of the Tuberoinfundibular Peptide (TIP)39/PTH2 Receptor System and Non-PTH1 Receptor-Mediated Tonic Effects of TIP39 and Other PTH2 Receptor Ligands in Renal Vessels
Published in Endocrinology (Philadelphia) (01-08-2002)“…Although lower than in brain, the type 2 PTH receptor (PTH2-R) has been shown to be expressed throughout the cardiovascular system. Tuberoinfundibular peptide…”
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Transcript expression of the tuberoinfundibular peptide (TIP)39/PTH2 receptor system and non-PTH1 receptor-mediated tonic effects of TIP39 and other PTH2 receptor ligands in renal vessels
Published in Endocrinology (Philadelphia) (01-08-2002)“…Although lower than in brain, the type 2 PTH receptor (PTH2-R) has been shown to be expressed throughout the cardiovascular system. Tuberoinfundibular peptide…”
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The nuclear receptor transcriptional coregulator RIP140
Published in Nuclear receptor signaling (30-10-2006)“…The nuclear receptor superfamily comprises ligand-regulated transcription factors that control various developmental and physiological pathways. These…”
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P-172: Replenishment of PTH1 receptor pool by peripheral receptor gene delivery reduces renal tonus in spontaneously hypertensive rats (SHR)
Published in American journal of hypertension (01-04-2001)“…A number of observations prompted us to explore the PTHrP system in renal vessels of SHR. First, the kidney is acknowledged as a major target of the dilatory…”
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P-357: Replenishment of PTH1 receptor pool by peripheral receptor gene delivery in spontaneously hypertensive rats (SHR) does not affect blood pressure but increases plasma renin activity
Published in American journal of hypertension (01-04-2001)“…In a parallel abstract, Massfelder et al. provide evidence for downregulation of PTH1 receptor (PTH1R) and upregulation of dilatory PTH-related protein (PTHrP)…”
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