Search Results - "FRISCHMEYER, Pamela A"
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A randomized, double-blind, placebo-controlled pilot study of sublingual versus oral immunotherapy for the treatment of peanut allergy
Published in Journal of allergy and clinical immunology (01-05-2015)“…Background Although promising results have emerged regarding oral immunotherapy (OIT) and sublingual immunotherapy (SLIT) for the treatment of peanut allergy…”
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Insights into the clinical, immunologic, and genetic underpinnings of food allergy
Published in Immunological reviews (01-09-2024)“…The last few decades have seen striking changes in the field of food allergy. The prevalence of the disease has risen dramatically in many parts of the globe,…”
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Key factors that influence quality of life in patients with IgE‐mediated food allergy vary by age
Published in Allergy (Copenhagen) (01-10-2024)“…Background While food allergy (FA) can be fatal, the greatest public health impact of FA arguably lies in its detrimental effect on quality of life (FAQOL)…”
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The safety and efficacy of sublingual and oral immunotherapy for milk allergy
Published in Journal of allergy and clinical immunology (01-02-2012)“…Background Oral immunotherapy (OIT) and sublingual immunotherapy (SLIT) are potential therapies for food allergy, but the optimal method of administration,…”
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Distinct CRTH2+CD161+ (peTh2) memory CD4+ T-cell cytokine profiles in food allergy and eosinophilic gastrointestinal disorders
Published in Clinical and experimental allergy (01-10-2023)“…Although IgE-mediated food allergy (FA) and eosinophilic gastrointestinal disorders (EGID) are clinically distinct and treated differently, pathogenic effector…”
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Profiling serum antibodies with a pan allergen phage library identifies key wheat allergy epitopes
Published in Nature communications (22-01-2021)“…Allergic reactions occur when IgE molecules become crosslinked by antigens such as food proteins. Here we create the ‘AllerScan’ programmable phage display…”
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Determinants of bone density in children with immunoglobulin E‐mediated food allergy
Published in Allergy (Copenhagen) (01-07-2023)Get full text
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Mechanistic correlates of clinical responses to omalizumab in the setting of oral immunotherapy for milk allergy
Published in Journal of allergy and clinical immunology (01-10-2017)“…Background In our recent clinical trial, the addition of omalizumab to oral immunotherapy (OIT) for milk allergy improved safety, but no significant clinical…”
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Suppression of the immunologic response to peanut during immunotherapy is often transient
Published in Journal of allergy and clinical immunology (01-05-2015)“…Background Studies suggest that oral immunotherapy (OIT) and sublingual immunotherapy (SLIT) for food allergy hold promise; however, the immunologic mechanisms…”
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Use of ondansetron for food protein–induced enterocolitis syndrome
Published in Journal of allergy and clinical immunology (01-11-2013)“…To the Editor: Food protein-induced enterocolitis syndrome (FPIES) is a non-IgE-mediated food allergy characterized by severe, repetitive vomiting that begins…”
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The Role of TGFβ and Other Cytokines in Regulating Mast Cell Functions in Allergic Inflammation
Published in International journal of molecular sciences (17-09-2022)“…Mast cells (MC) are a key effector cell in multiple types of immune responses, including atopic conditions. Allergic diseases have been steadily rising across…”
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Exosome-Mediated Recognition and Degradation of mRNAs Lacking a Termination Codon
Published in Science (American Association for the Advancement of Science) (22-03-2002)“…One role of messenger RNA (mRNA) degradation is to maintain the fidelity of gene expression by degrading aberrant transcripts. Recent results show that mRNAs…”
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Sex differences in neutrophil biology modulate response to type I interferons and immunometabolism
Published in Proceedings of the National Academy of Sciences - PNAS (14-07-2020)“…Differences between female and male immunity may contribute to variations in response to infections and predisposition to autoimmunity. We previously reported…”
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Web-based survey investigating cardiovascular complications in hypermobile Ehlers-Danlos syndrome after COVID-19 infection and vaccination
Published in PloS one (21-03-2024)“…Hypermobile Ehlers-Danlos syndrome is a heritable connective tissue disorder associated with generalized joint hypermobility but also other multisystem…”
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Oral health-related quality of life in Loeys-Dietz syndrome, a rare connective tissue disorder: an observational cohort study
Published in Orphanet journal of rare diseases (16-12-2019)“…Loeys-Dietz syndrome (LDS) is a rare connective tissue disorder whose oral manifestations and dental phenotypes have not been well-characterized. The aim of…”
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Prevalence and diagnosis of sesame allergy in children with IgE‐mediated food allergy
Published in Pediatric allergy and immunology (01-02-2020)“…Sesame allergy is estimated to affect 17% of children with IgE-mediated food allergy, and often co-occurs with peanut/tree nut sensitization and allergy…”
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Increased expression of formyl peptide receptor-1 by basophils from patients with mastocytosis
Published in The journal of allergy and clinical immunology. Global (01-11-2024)“…Symptoms in patients with systemic mastocytosis (SM) are associated with an increase in mast cell burden and release of mast cell–derived mediators. The most…”
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Safety and outcome of gastrostomy tube placement in patients with Loeys-Dietz syndrome
Published in BMC gastroenterology (12-03-2020)“…Loeys-Dietz syndrome (LDS) is a systemic connective tissue disease (CTD) associated with a predisposition for intestinal inflammation, food allergy, and…”
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Perturbation of thymocyte development in nonsense-mediated decay (NMD)-deficient mice
Published in Proceedings of the National Academy of Sciences - PNAS (28-06-2011)“…The random nature of T-cell receptor-β (TCR-β) recombination needed to generate immunological diversity dictates that two-thirds of alleles will be…”
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Investigation of Peanut-Specific T Effector (Teff) and T Regulatory (Treg) Cells in the Blood of Allergic and Non-Allergic Individuals
Published in Journal of allergy and clinical immunology (01-02-2017)“…Conclusions Established peanut allergy is not associated with a deficiency in or altered homing of peanut-specific Tregs in the blood…”
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