Search Results - "FRISCHER, Jason S"

Surgical Outcomes, Bowel Habits and Quality of Life in Young Patients after Ileoanal Anastomosis for Ulcerative Colitis by Knod, J. Leslie, Holder, Monica, Cortez, Alexander R, Martinez-Leo, Bruno, Kern, Patricia, Saeed, Shehzad, Warner, Brad, Dickie, Belinda, Falcone, Richard A, von Allmen, Daniel, Frischer, Jason S

“…Abstract Purpose We aim to investigate the post-operative outcomes, bowel habits and quality of life (QoL) of younger pediatric ulcerative colitis (UC)…”
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Complications in colorectal surgery by Frischer, Jason S., MD, Rymeski, Beth, DO

“…Abstract Colorectal pediatric surgery is a diverse field that encompasses many different procedures. The pull-through for Hirschsprung disease, the posterior…”
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Murine colitis treated with multitargeted tyrosine kinase inhibitors by Knod, Jennifer Leslie, MD, Crawford, Kelly, BS, Dusing, Mary, BS, Frischer, Jason S., MD

“…Abstract Background Angiogenesis, a known pathogenic component of neoplastic and nonneoplastic diseases, serves as a therapeutic target. Vascular endothelial…”
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Regression of Established Tumors and Metastases by Potent Vascular Endothelial Growth Factor Blockade by Huang, Jianzhong, Frischer, Jason S., Serur, Anna, Kadenhe, Angela, Yokoi, Akiko, McCrudden, Kimberly W., New, Tamara, O'Toole, Kathleen, Zabski, Stephanie, Rudge, John S., Holash, Jocelyn, Yancopoulos, George D., Yamashiro, Darrell J., Kandel, Jessica J.

“…Vascular endothelial growth factor (VEGF) is a critical promoter of blood vessel growth during embryonic development and tumori-genesis. To date, studies of…”
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Potent VEGF Blockade Causes Regression of Coopted Vessels in a Model of Neuroblastoma by Kim, Eugene S., Serur, Anna, Huang, Jianzhong, Manley, Christina A., McCrudden, Kimberly W., Frischer, Jason S., Soffer, Samuel Z., Ring, Laurence, New, Tamara, Zabski, Stephanie, Rudge, John S., Holash, Jocelyn, Yancopoulos, George D., Kandel, Jessica J., Yamashiro, Darrell J.

“…Vascular endothelial growth factor (VEGF) plays a key role in human tumor angiogenesis. We compared the effects of inhibitors of VEGF with different…”
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Mouse strain influences angiogenic response to dextran sodium sulfate–induced colitis by Knod, Jennifer Leslie, MD, Crawford, Kelly, BS, Dusing, Mary, BS, Frischer, Jason S., MD

“…Abstract Background Angiogenesis is a known pathologic factor in chronic inflammatory diseases. Regarding the murine dextran sodium sulfate (DSS) colitis…”
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EGFR Inhibition Fails to Suppress Vascular Proliferation and Tumor Growth in a Ewing's Sarcoma Model by Chernoguz, Artur, M.D, Crawford, Kelly, B.S, Donovan, Eileen, Vandersall, Abbey, Berglund, Caroline, B.S, Cripe, Timothy P., M.D., Ph.D, Frischer, Jason S., M.D

“…Background Expression of epidermal growth factor receptor (EGFR), a potent regulator of cellular homeostasis, is associated with aggressive tumor behavior. The…”
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Vascular endothelial growth factor receptor-2 inhibition in experimental murine colitis by Knod, Leslie, MD, Donovan, Eileen C., BS, Chernoguz, Artur, MD, Crawford, Kelly M., BS, Dusing, Mary R., BS, Frischer, Jason S., MD

“…Abstract Background In the setting of inflammatory bowel disease, inflammation is associated with a simultaneous increase in angiogenesis; moreover, elevated…”
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Sacral Nerve Stimulation in Children with Medically Refractory Fecal Incontinence or Severe Constipation by Trinidad, Stephen, Jensen, Amanda, Holder, Monica, Elsner, Allison, Rosen, Nelson, Garrison, Aaron, Rymeski, Beth, Frischer, Jason S.

“…The goal of this study was to evaluate outcomes in patients treated with sacral nerve stimulation (SNS) for medically refractory fecal incontinence or severe…”
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Surgical management of complicated Crohn's disease by Ullrich, Sarah J., Frischer, Jason S.

“…Surgical management of pediatric Crohn's disease is fundamentally palliative, aiming to treat the sequalae of complicated disease while preserving intestinal…”
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Surgical history of Hirschsprung disease by Jensen, Amanda R., Frischer, Jason S.

“…Harald Hirschsprung presented the first comprehensive and detailed description of clinical outcomes in patients with congenital megacolon. In the century…”
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Concurrent esophageal atresia with tracheoesophageal fistula and Hirschsprung disease by Knod, J. Leslie, Bondoc, Alexander J, Garrison, Aaron P, Bischoff, Andrea, Dickie, Belinda, Frischer, Jason S

“…Abstract We describe two cases of concomitant Hirschsprung disease and esophageal atresia and tracheoesophageal fistula in the newborn, both of which were…”
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Cancer screening by systemic administration of a gene delivery vector encoding tumor-selective secretable biomarker expression by Browne, Andrew W, Leddon, Jennifer L, Currier, Mark A, Williams, Jon P, Frischer, Jason S, Collins, Margaret H, Ahn, Chong H, Cripe, Timothy P

“…Cancer biomarkers facilitate screening and early detection but are known for only a few cancer types. We demonstrated the principle of inducing tumors to…”
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Hirschsprung-Associated Enterocolitis at a Referral Institution: A Retrospective Review by Encisco, Ellen M., Lim, Irene Isabel P., Velazco, Cristine S., Rosen, Nelson G., Garrison, Aaron P., Rymeski, Beth, Frischer, Jason S.

“…Hirschsprung-associated enterocolitis (HAEC) is the most common cause of morbidity and mortality amongst patients with Hirschsprung disease (HD); rectal…”
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Long-Term Male Sexual Function and Fecal Incontinence Outcomes for Adult Patients with Hirschsprung Disease or Anorectal Malformation by Trinidad, Stephen, Garrison, Aaron, Encisco, Ellen M., Canteria, Rey, VanderBrink, Brian, Strine, Andrew, Reddy, Pramod, Kotagal, Meera, Rosen, Nelson, Rymeski, Beth, Frischer, Jason S.

“…This study sought to characterize sexual function and fecal incontinence related quality of life (QOL) outcomes for adult males with anorectal malformation…”
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Does Length of Extended Resection Beyond Transition Zone Change Clinical Outcome for Hirschsprung Pull-Through? by Ullrich, Sarah, Denning, Naomi-Liza, Holder, Monica, Wittenberg, Randi, Krebs, Kevin, Schwan, Ava, Verderber, Abigail, Garrison, Aaron P., Rymeski, Beth, Rosen, Nelson, Frischer, Jason S.

“…A proximal resection margin greater than 5 cm from the intra-operative histologically determined transition zone has been deemed necessary to minimize the risk…”
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Hirschsprung's disease in low- and middle-income countries by Trinidad, Stephen, Kayima, Peter, Kotecha, Vihar, Massenga, Alicia, Rymeski, Beth, Frischer, Jason S., Situma, Martin, Kotagal, Meera

“…Hirschsprung's disease (HD) is one of the most common causes of pediatric bowel obstruction in low- and middle-income countries (LMICs). This paper describes…”
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Evaluation and Management of Total Colonic Hirschsprung Disease: A Comprehensive Review From the American Pediatric Surgical Association (APSA) Hirschsprung Disease Interest Group by Rentea, Rebecca M., Bokova, Elizaveta, Frischer, Jason S., Gosain, Ankush, Langer, Jacob C., Levitt, Marc A., Nandivada, Prathima, Rialon, Kristy L., Rollins, Michael D., Segura, Bradley, Wood, Richard J., Lim, Irene Isabel P.

“…Children with total colonic Hirschsprung disease (TCHD) are a unique group of patients with pre- and postoperative management challenges. This review provides…”
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What Happens Post-Malone? An Investigation of Long-Term Postoperative Management of Antegrade Continence Enemas by Encisco, Ellen M., Garza, Ramiro, McNinch, Neil L., Davis, Carolyn, Rosen, Nelson G., Rymeski, Beth, Frischer, Jason S., Garrison, Aaron P., Huntington, Justin T.

“…An option for medically refractory fecal incontinence and/or constipation is the antegrade continence enema (ACE). We investigated ACE usage and its…”
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Hemorrhage after on-ECMO repair of CDH is equivalent for muscle flap and prosthetic patch by Nolan, Heather, Aydin, Emrah, Frischer, Jason S., Peiro, Jose L., Rymeski, Beth, Lim, Foong-Yen

“…Prosthetic patch (patch) and muscle flap (flap) techniques are utilized for severe congenital diaphragmatic hernia (CDH) repair; however, when performed on…”
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