Search Results - "FRIESE, P"

Bax activators potentiate coated‐platelet formation by DALE, G. L., FRIESE, P.

“…Background: Activation of platelets with collagen plus thrombin produces a subset of cells known as coated‐platelets. Coated‐platelets retain several α‐granule…”
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Scott syndrome dogs have impaired coated‐platelet formation and calcein‐release but normal mitochondrial depolarization by BROOKS, M. B., CATALFAMO, J. L., FRIESE, P., DALE, G. L.

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Quantitation of microparticles released from coated‐platelets by DALE, G. L., REMENYI, G., FRIESE, P.

“…Dual agonist stimulation of platelets with thrombin and convulxin results in generation of coated‐platelets, a sub‐population of cells known formerly as…”
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Characterizing Evolutionary Dynamics Reveals Strategies to Exhaust the Spectrum of Subclonal Resistance in EGFR-Mutant Lung Cancer by Müller, Nina, Lorenz, Carina, Ostendorp, Jenny, Heisel, Felix S, Friese, Ulrich P, Cartolano, Maria, Plenker, Dennis, Tumbrink, Hannah, Heimsoeth, Alena, Baedeker, Philipp, Weiss, Jonathan, Ortiz-Cuaran, Sandra, Büttner, Reinhard, Peifer, Martin, Thomas, Roman K, Sos, Martin L, Berg, Johannes, Brägelmann, Johannes

“…The emergence of resistance to targeted therapies restrains their efficacy. The development of rationally guided drug combinations could overcome this…”
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Human Interleukin 6 is a Direct Promoter of Maturation of Megakaryocytes in vitro by Ishibashi, Toshiyuki, Kimura, Hideo, Uchida, Tatsumi, Kariyone, Shigeo, Friese, Paul, Burstein, Samuel A.

“…The response of cells of the murine megakaryocytic lineage to human interleukin 6 (IL-6) was assessed in serum-depleted cultures using a variety of biological…”
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Collagen response and glycoprotein VI function decline progressively as canine platelets age in vivo by Alberio, L, Friese, P, Clemetson, K J, Dale, G L

“…Clinical and experimental observations suggest that platelet function deteriorates quickly with cell age. However, efforts to define age-dependent alterations…”
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Aged Platelets Have an Impaired Response to Thrombin as Quantitated by P-Selectin Expression by Peng, Jinpeng, Friese, Paul, Heilmann, Eric, George, James N., Burstein, Samuel A., Dale, George L.

“…After the intravenous infusion of N-hydroxysuccinimido biotin into dogs, 80.6% ± 9.7% (n = 5) of platelets were covalently labeled with biotin. The in vivo…”
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Biotinylated platelets: a new approach to the measurement of platelet life span by Heilmann, E, Friese, P, Anderson, S, George, J N, Hanson, S R, Burstein, S A, Dale, G L

“…The in vivo life span of dog platelets was determined by derivatizing whole blood with N-hydroxysuccinimido biotin, reinfusing the biotinylated blood and…”
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Quantitation of platelet life span in splenectomized dogs by Dale, G L, Wolf, R F, Hynes, L A, Friese, P, Burstein, S A

“…Platelet life spans in dogs were measured pre- and post- splenectomy utilizing in vitro whole blood biotinylation. Four splenectomized dogs were found to have…”
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Characteristics of a novel rat anti-mouse platelet monoclonal antibody: application to studies of megakaryocytes by Burstein, S A, Friese, P, Downs, T, Mei, R L

“…Using murine platelets as an immunogen, a rat monoclonal antibody (designated 4A5) that recognizes only murine blood platelets and marrow megakaryocytes was…”
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Role of Mitochondrial Permeability Transition Pore in Coated-Platelet Formation by Remenyi, Gyula, Szasz, Robert, Friese, Paul, Dale, George L

“…OBJECTIVE—Coated-platelets are a subset of cells observed during costimulation of platelets with collagen and thrombin. Important characteristics of…”
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Dog platelets accumulate intracellular fibrinogen as they age by Heilmann, E, Hynes, L A, Friese, P, George, I N, Burstein, S A, Dale, G L

“…The alpha granules of circulating platelets are dynamic structures that acquire endogenous and exogenous components by synthesis and uptake, respectively. The…”
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Flow Cytometric Analysis of Megakaryocytes From Patients With Abnormal Platelet Counts by Tomer, Aaron, Friese, Paul, Conklin, Richard, Bales, Wes, Archer, Linda, Harker, Laurence A., Burstein, Samuel A.

“…Megakaryocytes (MKs) from 40 patients with quantitative platelet disorders and 19 normal volunteers were analyzed by flow cytometry for size, fine cell…”
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Stimulated platelets use serotonin to enhance their retention of procoagulant proteins on the cell surface by Dale, George L, Friese, Paul, Batar, Peter, Hamilton, Stephen F, Reed, Guy L, Jackson, Kenneth W, Clemetson, Kenneth J, Alberio, Lorenzo

“…Activated platelets bind numerous adhesive and procoagulant proteins by receptor-mediated processes. Although there is little evidence to suggest that these…”
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Aged platelets have an impaired response to thrombin as quantitated by P-selectin expression by Peng, J, Friese, P, Heilmann, E, George, JN, Burstein, SA, Dale, GL

“…After the intravenous infusion of N-hydroxysuccinimido biotin into dogs, 80.6% +/- 9.7% (n = 5) of platelets were covalently labeled with biotin. The in vivo…”
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Canine megakaryocytopoiesis: analysis utilizing a monoclonal antibody to a 140-kd dog platelet protein by Burstein, S A, Friese, P, Downs, T, Epstein, R E

“…The dog, a convenient and relatively large animal whose size permits repetitive blood and marrow sampling, marrow biopsy, and mechanical apheresis, would be a…”
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Job sharing, a solution to the personal energy crisis by Friese, P, Stefura, E

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Flow cytometric analysis of megakaryocytes (Mks) from patients with platelet disorders by Conklin, R J, Tomer, A, Friese, P, Bales, W, Burstein, S A

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Demonstration that thiazole-orange-positive platelets in the dog are less than 24 hours old by DALE, G. L, FRIESE, P, HYNES, L. A, BURSTEIN, S. A

“…Approximately 6% of dog platelets are positive for staining with thiazole orange, a dye frequently used to stain ribonucleic acid. In this report,…”
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Erythropoietin administration increases production and reactivity of platelets in dogs by Wolf, R F, Peng, J, Friese, P, Gilmore, L S, Burstein, S A, Dale, G L

“…Administration of erythropoietin (EPO) to adult dogs resulted in a dramatic increase in the number of thiazole orange-positive (TO+) platelets, also referred…”
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