Search Results - "FRIEDRICH, P"

Magnetic nanoparticle-based drug delivery for cancer therapy by Tietze, Rainer, Zaloga, Jan, Unterweger, Harald, Lyer, Stefan, Friedrich, Ralf P., Janko, Christina, Pöttler, Marina, Dürr, Stephan, Alexiou, Christoph

“…Nanoparticles have belonged to various fields of biomedical research for quite some time. A promising site-directed application in the field of nanomedicine is…”
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Iron Oxide Nanoparticles in Regenerative Medicine and Tissue Engineering by Friedrich, Ralf P., Cicha, Iwona, Alexiou, Christoph

“…In recent years, many promising nanotechnological approaches to biomedical research have been developed in order to increase implementation of regenerative…”
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EGCG remodels mature α-synuclein and amyloid-β fibrils and reduces cellular toxicity by Bieschke, Jan, Russ, Jenny, Friedrich, Ralf P, Ehrnhoefer, Dagmar E, Wobst, Heike, Neugebauer, Katja, Wanker, Erich E

“…Protein misfolding and formation of β-sheet-rich amyloid fibrils or aggregates is related to cellular toxicity and decay in various human disorders including…”
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Phosphorylation, nitrosation and plasminogen K3 modulation make VDAC-1 lucid as part of the extrinsic apoptotic pathway—Resulting thesis: Native VDAC-1 indispensible for finalisation of its 3D structure by Thinnes, Friedrich P.

“…Native and recombinant VDAC preparations differ in their acetylation, phosphorylation and nitrosation state; additionally, proteineous modulators are missing…”
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Mechanism of amyloid plaque formation suggests an intracellular basis of Aβ pathogenicity by Friedrich, Ralf P, Tepper, Katharina, Rönicke, Raik, Soom, Malle, Westermann, Martin, Reymann, Klaus, Kaether, Christoph, Fändrich, Marcus

“…The formation of extracellular amyloid plaques is a common patho-biochemical event underlying several debilitating human conditions, including Alzheimer's…”
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Nonmelanoma skin cancer is associated with reduced Alzheimer disease risk by Thinnes, Friedrich P

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Comparison of techniques to control the aggressive environmental invasive species Galenia pubescens in a degraded grassland reserve, Victoria, Australia by Mahmood, Ako H, Florentine, Singarayer, Graz, Friedrich P, Turville, Christopher, Palmer, Grant, Sillitoe, James, McLaren, David

“…Across many southern regions of Australia, native grasslands have become seriously threatened by human activity, with only a fraction of the original areas…”
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Optimization of cell seeding on electrospun PCL-silk fibroin scaffolds by Singh, Raminder, Eitler, David, Morelle, René, Friedrich, Ralf P., Dietel, Barbara, Alexiou, Christoph, Boccaccini, Aldo R., Liverani, Liliana, Cicha, Iwona

“…[Display omitted] •PCL and silk fibroin (SF) blended fibers are electrospun using benign solvents.•Growth of primary endothelial cells and fibroblasts is…”
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CXCR4 and CXCR7 Mediate TFF3-Induced Cell Migration Independently From the ERK1/2 Signaling Pathway by Dieckow, Julia, Brandt, Wolfgang, Hattermann, Kirsten, Schob, Stefan, Schulze, Ute, Mentlein, Rolf, Ackermann, Philipp, Sel, Saadettin, Paulsen, Friedrich P

“…Trefoil factor family (TFF) peptides, and in particular TFF3, are characteristic secretory products of mucous epithelia that promote antiapoptosis, epithelial…”
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Mitoxantrone and Mitoxantrone-Loaded Iron Oxide Nanoparticles Induce Cell Death in Human Pancreatic Ductal Adenocarcinoma Cell Spheroids by Dinter, Jonas, Friedrich, Ralf P, Yang, Hai, Pilarsky, Christian, Mangge, Harald, Pöttler, Marina, Janko, Christina, Alexiou, Christoph, Lyer, Stefan

“…Pancreatic ductal adenocarcinoma is a hard-to-treat, deadly malignancy. Traditional treatments, such as surgery, radiation and chemotherapy, unfortunately are…”
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Contact Guidance by Microstructured Gelatin Hydrogels for Prospective Tissue Engineering Applications by Tadsen, Meike, Friedrich, Ralf P, Riedel, Stefanie, Alexiou, Christoph, Mayr, Stefan G

“…Design of functionalized biomimetic scaffolds is one of the key approaches for regenerative medicine and other biomedical applications. Development of…”
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Opening up of plasmalemma type-1 VDAC to form apoptotic “find me signal” pathways is essential in early apoptosis — Evidence from the pathogenesis of cystic fibrosis resulting from failure of apoptotic cell clearance followed by sterile inflammation by Thinnes, Friedrich P.

“…Cell membrane-standing type-1 VDAC is involved in cell volume regulation and thus apoptosis. The channel has been shown to figure as a pathway for osmolytes of…”
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Nanomedicine for vaccination and diagnosis of diseases by Lyer, Stefan, Janko, Christina, P Friedrich, Ralf, Cicha, Iwona, Tietze, Rainer, Unterweger, Harald, Alexiou, Christoph

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The growth and differentiation of mesenchymal stem and progenitor cells cultured on aligned collagen matrices by Lanfer, Babette, Seib, Friedrich P, Freudenberg, Uwe, Stamov, Dimitar, Bley, Thomas, Bornhäuser, Martin, Werner, Carsten

“…Abstract Cell-matrix interactions are paramount for the successful repair and regeneration of damaged and diseased tissue. Since many tissues have an…”
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New findings concerning vertebrate porin II — On the relevance of glycine motifs of type-1 VDAC by Thinnes, Friedrich P.

“…New findings concerning vertebrate porin part I was published in 1997, then summarizing early data and reflections regarding the molecular structure of…”
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On GxxxG in N-terminal stretches of type-1 VDAC/porin: critical in vertebrate apoptosis, missing in plants by Thinnes, Friedrich P.

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Isolation and Investigation of Presumptive Murine Lacrimal Gland Stem Cells by Ackermann, Philipp, Hetz, Susann, Dieckow, Julia, Schicht, Martin, Richter, Anja, Kruse, Charli, Schroeder, Insa S, Jung, Matthias, Paulsen, Friedrich P

“…Aqueous tear deficiency due to lacrimal gland insufficiency is one of the major causes of dry eye disease. In severe cases, such as Sjogren's syndrome,…”
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Examination of the current top candidate genes for AD in a genome-wide association study by Feulner, T M, Laws, S M, Friedrich, P, Wagenpfeil, S, Wurst, S H R, Riehle, C, Kuhn, K A, Krawczak, M, Schreiber, S, Nikolaus, S, Förstl, H, Kurz, A, Riemenschneider, M

“…With the advent of technologies that allow simultaneous genotyping of thousands of single-nucleotide polymorphisms (SNPs) across the genome, the genetic…”
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Assessing the Spatial Drivers of Land Use and Land Cover Change in the Protected and Communal Areas of the Zambezi Region, Namibia by Kamwi, Jonathan, Cho, Moses, Kaetsch, Christoph, Manda, Samuel, Graz, Friedrich, Chirwa, Paxie

“…Understanding the patterns and drivers of land use and land cover (LULC) changes is fundamental for rational and specific planning for sustainable land…”
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Why cancer survivors have a lower risk of Alzheimer disease by Thinnes, Friedrich P.

“…Tying up two recent lines of experimental evidence may help explain this vital issue. On the one hand, data indicate that cancerous transformations of cells…”
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