Search Results - "FRIEDMAN, A. H"

Metronomic chemotherapy with daily, oral etoposide plus bevacizumab for recurrent malignant glioma: a phase II study by Reardon, D A, Desjardins, A, Vredenburgh, J J, Gururangan, S, Sampson, J H, Sathornsumetee, S, McLendon, R E, Herndon, J E, Marcello, J E, Norfleet, J, Friedman, A H, Bigner, D D, Friedman, H S

“…Background: We evaluated bevacizumab with metronomic etoposide among recurrent malignant glioma patients in a phase 2, open-label trial. Methods: A total of 59…”
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Bevacizumab continuation beyond initial bevacizumab progression among recurrent glioblastoma patients by Reardon, D A, Herndon, J E, Peters, K B, Desjardins, A, Coan, A, Lou, E, Sumrall, A L, Turner, S, Lipp, E S, Sathornsumetee, S, Rich, J N, Sampson, J H, Friedman, A H, Boulton, S T, Bigner, D D, Friedman, H S, Vredenburgh, J J

“…Background: Bevacizumab improves outcome for most recurrent glioblastoma patients, but the duration of benefit is limited and survival after initial…”
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Seizure outcome after temporal lobectomy for temporal lobe epilepsy: A Kaplan-Meier survival analysis by FOLDVARY, N, NASHOLD, B, MASCHA, E, THOMPSON, E. A, LEE, N, MCNAMARA, J. O, LEWIS, D. V, LUTHER, J. S, FRIEDMAN, A. H, RADTKE, R. A

“…To determine seizure outcome and its predictors in patients with medically refractory temporal lobe epilepsy (TLE) after temporal lobectomy (TL). TL is the…”
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DNA mismatch repair and O6-alkylguanine-DNA alkyltransferase analysis and response to Temodal in newly diagnosed malignant glioma by Friedman, H S, McLendon, R E, Kerby, T, Dugan, M, Bigner, S H, Henry, A J, Ashley, D M, Krischer, J, Lovell, S, Rasheed, K, Marchev, F, Seman, A J, Cokgor, I, Rich, J, Stewart, E, Colvin, O M, Provenzale, J M, Bigner, D D, Haglund, M M, Friedman, A H, Modrich, P L

“…We evaluated the response to Temodal (Schering-Plough Research Institute, Kenilworth, NJ) of patients with newly diagnosed malignant glioma, as well as the…”
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Demographics, prognosis, and therapy in 702 patients with brain metastases from malignant melanoma by SAMPSON, J. H, CARTER, J. H, FRIEDMAN, A. H, SEIGLER, B. F

“…Brain metastases are a common and devastating complication in patients with malignant melanoma. Therapeutic options for these patients are limited, and the…”
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Cell surface localization and density of the tumor-associated variant of the epidermal growth factor receptor, EGFRvIII by WIKSTRAND, C. J, MCLENDON, R. E, FRIEDMAN, A. H, BIGNER, D. D

“…The potential of therapeutic targeting of tumor cell surface epidermal growth factor receptors (EGFRs) by modified ligands or specific antibodies has been…”
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Treatment of radiation-induced nervous system injury with heparin and warfarin by GLANTZ, M. J, BURGER, P. C, FRIEDMAN, A. H, RADTKE, R. A, MASSEY, E. W, SCHOLD, S. C

“…When radiation is used to treat nervous system cancer, exposure of adjacent normal nervous system tissue is unavoidable, and radiation-induced injury may…”
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PTEN gene mutations are seen in high-grade but not in low-grade gliomas by AHMED RASHEED, B. K, STENZEL, T. T, MCLENDON, R. E, PARSONS, R, FRIEDMAN, A. H, FRIEDMAN, H. S, BIGNER, D. D, BIGNER, S. H

“…The PTEN gene, located on 10q23, has recently been implicated as a candidate tumor suppressor gene in brain, breast and prostate tumors. In the present study,…”
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Irinotecan Therapy in Adults With Recurrent or Progressive Malignant Glioma by FRIEDMAN, H. S, PETROS, W. P, CLOUGHSEY, T, STEWART, E. S, COLVIN, O. M, PROVENZALE, J. M, MCLENDON, R. E, BIGNER, D. D, COKGOR, L, HAGLUND, M, RICH, J, ASHLEY, D, FRIEDMAN, A. H, MALCZYN, J, ELFRING, G. L, MILLER, L. L, SCHAAF, L. J, KERBY, T, LAWYER, J, PARRY, M, HOUGHTON, P. J, LOVELL, S, RASHEED, K

“…To determine the activity, toxicity, and pharmacokinetics of irinotecan (CPT-11, Camptosar; Pharmacia & Upjohn, Kalamazoo, MI) in the treatment of adults with…”
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Impact of Ruptured Cerebral Aneurysm Coiling and Clipping on the Incidence of Cerebral Vasospasm and Clinical Outcome by Zaidat, O. O., Ionita, C. C., Hussain, S. I., Alexander, M. J., Friedman, A. H., Graffagnino, C.

“…ABSTRACT BACKGROUND This study assessed the impact of treatment modality of aneurysmal subarachnoid hemorrhage (aSAH) on the rate of vasospasm (VSP),…”
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Molecular Genetic Aspects of Oligodendrogliomas Including Analysis by Comparative Genomic Hybridization by Bigner, Sandra H., Matthews, Mark R., Rasheed, B.K.A., Wiltshire, Rodney N., Friedman, Henry S., Friedman, Allan H., Stenzel, Timothy T., Dawes, Donald M., McLendon, Roger E., Bigner, Darell D.

“…Oligodendroglial neoplasms are a subgroup of gliomas with distinctive morphological characteristics. In the present study we have evaluated a series of these…”
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Correlation of Hippocampal Neuronal Density and FDG‐PET in Mesial Temporal Lobe Epilepsy by Foldvary, N., Lee, N., Hanson, M. W., Coleman, R. E., Hulette, C. M., Friedman, A. H., Bej, M. D., Radtke, R. A.

“…Purpose: Interictal [18F]fluorodeoxyglucose (FDG) positron emission tomography (PET) reveals regional hypometabolism in 60–80% of patients with mesial temporal…”
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Gliomas of the optic nerve : histological, immunohistochemical (MIB-1 and p53), and MRI analysis by CUMMINGS, T. J, PROVENZALE, J. M, HUNTER, S. B, FRIEDMAN, A. H, KLINTWORTH, G. K, BIGNER, S. H, MCLENDON, R. E

“…Gliomas of the optic nerve, although typically of pilocytic (WHO grade I) histology, can present within the spectrum of astrocytic neoplasia including…”
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Interstitial chemotherapy with drug polymer implants for the treatment of recurrent gliomas by BREM, H, MAHALEY, S. JR, KENEALY, J. N, VICK, N. A, BLACK, K. L, SCHOLD, S. C, BURGER, P. C, FRIEDMAN, A. H, CIRIC, I. S, ELLER, T. W, COZZENS, J. W

“…Malignant gliomas have been difficult to treat with chemotherapy. The most effective agent, BCNU (carmustine), has considerable systemic toxicity and a short…”
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Clinical and electrographic manifestations of lesional neocortical temporal lobe epilepsy by FOLDVARY, N, LEE, N, THWAITES, G, MASCHA, E, HAMMEL, J, KIM, H, FRIEDMAN, A. H, RADTKE, R. A

“…To determine whether lesional neocortical temporal lobe epilepsy (NTLE) can be differentiated from mesial temporal lobe epilepsy (MTLE) during the noninvasive…”
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Fractionated external-beam radiation therapy for meningiomas of the cavernous sinus by Maguire, P D, Clough, R, Friedman, A H, Halperin, E C

“…Despite advances in microsurgical technique, many cavernous sinus meningiomas remain unresectable or only partially resectable, prompting referral of patients…”
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Iodine-131-labeled antitenascin monoclonal antibody 81C6 treatment of patients with recurrent malignant gliomas: phase I trial results by Bigner, D D, Brown, M T, Friedman, A H, Coleman, R E, Akabani, G, Friedman, H S, Thorstad, W L, McLendon, R E, Bigner, S H, Zhao, X G, Pegram, C N, Wikstrand, C J, Herndon, 2nd, J E, Vick, N A, Paleologos, N, Cokgor, I, Provenzale, J M, Zalutsky, M R

“…To determine the maximum-tolerated dose (MTD) of iodine 131 (131I)-labeled 81C6 monoclonal antibody (mAb) in brain tumor patients with surgically created…”
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Temporal lobe hypometabolism on PET : predictor of seizure control after temporal lobectomy by RADTKE, R. A, HANSON, M. W, HOFFMAN, J. M, CRAIN, B. J, WALECZAK, T. S, LEWIS, D. V, BEAM, C, COLEMAN, R. E, FRIEDMAN, A. H

“…To investigate the relationship of temporal lobe hypometabolism demonstrated on PET to surgical outcome and underlying pathology, we reviewed 30 consecutive…”
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Alterations of the TP53 gene in human gliomas by AHMED RESHEED, B. K, MCLENDON, R. E, HERNDON, J. E, FRIEDMAN, H. S, FRIEDMAN, A. H, BIGNER, D. D, BIGNER, S. H

“…Glial tumors of all grades and histological types from 72 adults and 48 children were analyzed for mutations of the TP53 gene, loss of heterozygosity (LOH) for…”
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Malignant peripheral nerve sheath tumor of the spine after radiation therapy for Hodgkin's lymphoma by Adamson, D C, Cummings, T J, Friedman, A H

“…We report the development of a malignant peripheral nerve sheath tumor (MPNST) in 2 patients after irradiation for Hodgkin's lymphoma. Clinicians should be…”
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