Search Results - "FRIEBOES, R. M"

Prediction of Medium-Term Outcome by Cortisol Response to the Combined Dexamethasone-CRH Test in Patients With Remitted Depression by Zobel, Astrid W., Yassouridis, Alexander, Frieboes, Ralf-Michael, Holsboer, Florian

“…OBJECTIVE: Current hypotheses hold that mechanisms underlying abnormal hypothalamic-pituitary-adrenocortical (HPA) function are causal factors in the…”
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Elevated nocturnal profiles of serum leptin in patients with depression by Antonijevic, I.a., Murck, H., Frieboes, R.-M., Horn, R., Brabant, G., Steiger, A.

“…Leptin, the protein product of the obese ( ob) gene, has been suggested to play a role in the regulation of food intake. As depressive episodes are frequently…”
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On the role of menopause for sleep-endocrine alterations associated with major depression by Antonijevic, I.A., Murck, H., Frieboes, R.-M., Uhr, M., Steiger, A.

“…Aging and menopause are associated with alterations of the sleep EEG, while age-related changes of the hypothalamo-pituitary-adrenal (HPA) axis remain…”
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Neuropeptide Y promotes sleep and inhibits ACTH and cortisol release in young men by Antonijevic, Irina A, Murck, Harald, Bohlhalter, Stephan, Frieboes, Ralf-Michael, Holsboer, Florian, Steiger, Axel

“…Anxiolytic and sedative effects of neuropeptide Y (NPY) are thought to involve inhibition of corticotropin-releasing hormone (CRH). Enhanced secretion of CRH…”
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Clinical outcome after trimipramine in patients with delusional depression - a pilot study by Frieboes, R-M, Sonntag, A, Yassouridis, A, Eap, C B, Baumann, P, Steiger, A

“…The treatment of delusional depression is a major challenge in psychopharmacology. Hypothalamic-pituitary-adrenocortical (HPA) overdrive may contribute, via…”
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Distinct temporal pattern of the effects of the combined serotonin-reuptake inhibitor and 5-HT1A agonist EMD 68843 on the sleep EEG in healthy men by MURCK, H, FRIEBOES, R. M, ANTONIJEVIC, I. A, STEIGER, A

“…EMD 68843 (EMD) has properties of a serotonin (5-HT)-reuptake inhibitor and a partial 5-HT1A agonist in one molecule in order to combine antidepressive and…”
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Enhanced slow wave sleep in patients with prolactinoma by FRIEBOES, R.-M, MURCK, H, STALLA, G. K, ANTONIJEVIC, I. A, STEIGER, A

“…Bidirectional interactions between nocturnal hormone secretion and sleep regulation are well established. In particular, a link between PRL and rapid eye…”
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Open clinical trial on the sigma ligand panamesine in patients with schizophrenia by FRIEBOES, R.-M, MURCK, H, WIEDEMANN, K, HOLSBOER, F, STEIGER, A

“…The sigma (sigma) receptor has been proposed as a target of neuroleptic drugs. Preclinical data suggest that panamesine (EMD 57445), a novel sigma ligand, has…”
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Galanin has REM-sleep deprivation-like effects on the sleep eeg in healthy young men by Murck, H., Antonijevic, I.a., Frieboes, R.M., Maier, P., Schier, T., Steiger, A.

“…Rapid eye movement (REM) sleep deprivation leads to an induction of galanin gene expression in the rat brain, especially in the hypothalamus. Galanin affects…”
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Effects of Growth Hormone-Releasing Peptide-6 on the Nocturnal Secretion of GH, ACTH and Cortisol and on the Sleep EEG in Man: Role of Routes of Administration by Frieboes, R M, Murck, H, Antonijevic, I A, Steiger, A

“…After repeated intravenous (i.v.) boluses of growth hormone‐releasing peptide‐6 (GHRP‐6) we found recently increases of growth hormone (GH), corticotropin…”
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No association between dopamine D2 receptor gene (DRD2) and human intelligence by MOISES, H. W, FRIEBOES, R. M, SPELZHAUS, P, YANG, L, KÖHNKE, M, HERDEN-KIRCHHOFF, O, VETTER, P, NEPPERT, J, GOTTESMAN, I. I

“…Significantly diminished intellectual functioning, as indicated by appropriately administered IQ tests with scores below 70, is a frequent mental handicap…”
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Somatostatin Impairs Sleep in Elderly Human Subjects by FRIEBOES, R.-M, MURCK, H, SCHIER, T, HOLSBOER, F, STEIGER, A

“…With increasing age, sleep becomes more shallow and fragmented and sleep-associated growth hormone (GH) release declines. GH secretion is regulated…”
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VIP decelerates non-REM-REM cycles and modulates hormone secretion during sleep in men by Murck, H, Guldner, J, Colla-Müller, M, Frieboes, R M, Schier, T, Wiedemann, K, Holsboer, F, Steiger, A

“…Centrally administered vasoactive intestinal polypeptide (VIP) promotes rapid eye movement (REM) sleep in rats, rabbits, and cats. We studied the effect of 4 x…”
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Characterization of the sigma ligand panamesine, a potential antipsychotic, by immune response in patients with schizophrenia and by sleep-EEG changes in normal controls by FRIEBOES, R.-M, MURCK, H, ANTONIJEVIC, I, KRAUS, T, HINZE-SELCH, D, POLLMÄCHER, T, STEIGER, A

“…Panamesine (PAN) is a nearly specific sigma ligand. Recently, we showed that PAN in doses up to 90 mg/day improved psychometric variables in patients with an…”
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Effects of hormones on sleep by Steiger, A, Antonijevic, I A, Bohlhalter, S, Frieboes, R M, Friess, E, Murck, H

“…Administration of hormones to humans and animals results in specific effects on the sleep electroencephalogram (EEG) and nocturnal hormone secretion. Studies…”
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Longtime administration of growth hormone-releasing hormone (GHRH) does not restore the reduced efficiency of GHRH on sleep endocrine activity in 2 old-aged subjects--a preliminary study by Murck, H, Frieboes, R M, Schier, T, Steiger, A

“…Aging results in a more shallow sleep accompanied by a blunted growth hormone (GH) secretion. In young male normal controls repetitive administration of…”
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Aging does not affect the sleep endocrine response to total sleep deprivation in humans by Murck, Harald, Antonijevic, Irina A., Schier, Thomas, Frieboes, Ralf-Michael, Barthelmes, Jens, Steiger, Axel

“…Aging is associated with decreased sleep continuity, slow wave sleep (SWS), growth hormone (GH) release and an increased hypothalamo-pituitary-adrenocortical…”
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Sociotherapy in German social law. Indication, contents, and aspects of public health by Frieboes, R-M

“…In German mental health services, the ill-defined term "sociotherapy" has been used to designate nonmedical, social, and work-related components of the care…”
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Soziotherapie gemäß § 37a SGB V: Psychiatrische Indikation, Leistungsbeschreibung und sozialrechtlicher Hintergrund by Frieboes, R.-M.

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On the gender differences in sleep-endocrine regulation in young normal humans by Antonijevic, I A, Murck, H, Frieboes, R, Holsboer, F, Steiger, A

“…Sleep-endocrine regulation in humans involves high activity of the somatotropic axis at the beginning of the night and an increase in the…”
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