Search Results - "FREUND, G"

The health benefits of dietary fiber: Beyond the usual suspects of type 2 diabetes mellitus, cardiovascular disease and colon cancer by Kaczmarczyk, Melissa M, Miller, Michael J, Freund, Gregory G

“…Abstract Dietary fiber (DF) is deemed to be a key component in healthy eating. DF is not a static collection of undigestible plant materials that pass…”
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IL-1 receptor 2 (IL-1R2) and its role in immune regulation by Peters, Vanessa A, Joesting, Jennifer J, Freund, Gregory G

“…Highlight ► The first dedicated comprehensive review of IL-1R2 in the biomedical literature…”
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From inflammation to sickness and depression: when the immune system subjugates the brain by Dantzer, Robert, O'Connor, Jason C, Freund, Gregory G, Johnson, Rodney W, Kelley, Keith W

“…Key Points Infections cause people to become sick and change their behaviour. They develop fever, sleep poorly, eat less, experience difficulty with memory and…”
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Neuroinflammation and disruption in working memory in aged mice after acute stimulation of the peripheral innate immune system by Chen, Jing, Buchanan, Jessica B, Sparkman, Nathan L, Godbout, Jonathan P, Freund, Gregory G, Johnson, Rodney W

“…Abstract Acute cognitive disorders are common in elderly patients with peripheral infections but it is not clear why. Here, we injected old and young mice with…”
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Systematic review of barriers and enablers to the delivery of palliative care by primary care practitioners by Carey, Mariko L, Zucca, Alison C, Freund, Megan AG, Bryant, Jamie, Herrmann, Anne, Roberts, Bernadette J

“…Background: There is increasing demand for primary care practitioners to play a key role in palliative care delivery. Given this, it is important to understand…”
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The saturated fatty acid, palmitic acid, induces anxiety-like behavior in mice by Moon, Morgan L, Joesting, Jennifer J, Lawson, Marcus A, Chiu, Gabriel S, Blevins, Neil A, Kwakwa, Kristin A, Freund, Gregory G

“…Abstract Objectives Excess fat in the diet can impact neuropsychiatric functions by negatively affecting cognition, mood and anxiety. We sought to show that…”
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Central inhibition of interleukin-6 trans -signaling during peripheral infection reduced neuroinflammation and sickness in aged mice by Burton, Michael D, Rytych, Jennifer L, Freund, Gregory G, Johnson, Rodney W

“…Highlight ► The involvement of IL-6 trans-signaling on exaggerated sickness in the aged is identified.·► A cellular source of exaggerated central IL-6 is…”
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The effect of hypergravity, hyperbaric pressure, and hypoxia on osteogenic differentiation of adipose stem cells by Lingens, L.F., Ruhl, T., Beier, J.P., Mende, W., Freund, G., Götzl, R.

“…Human adipose stem cells (ASCs) hold great potential for regenerative medicine approaches, including osteogenic regeneration of bone defects, that fail to heal…”
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Exposure to a firefighting overhaul environment without respiratory protection increases immune dysregulation and lung disease risk by Gainey, Stephen J, Horn, Gavin P, Towers, Albert E, Oelschlager, Maci L, Tir, Vincent L, Drnevich, Jenny, Fent, Kenneth W, Kerber, Stephen, Smith, Denise L, Freund, Gregory G

“…Firefighting activities appear to increase the risk of acute and chronic lung disease, including malignancy. While self-contained breathing apparatuses (SCBA)…”
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Fasting Induces an Anti-Inflammatory Effect on the Neuroimmune System Which a High-Fat Diet Prevents by Lavin, Desiree N., Joesting, Jennifer J., Chiu, Gabriel S., Moon, Morgan L., Meng, Jia, Dilger, Ryan N., Freund, Gregory G.

“…The neuroimmunological and behavioral consequences of a high‐fat diet (HFD) are not well delineated. This is especially true when short term (24 h) fasting is…”
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Switching from a high-fat cellulose diet to a high-fat pectin diet reverses certain obesity-related morbidities by Bray, Julie K, Chiu, Gabriel S, McNeil, Leslie K, Moon, Morgan L, Wall, Robyn, Towers, Albert E, Freund, Gregory G

“…Reducing caloric intake is a proven intervention for mitigating and modulating morbidities associated with overnutrition. Caloric restriction is difficult to…”
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Glial and tissue-specific regulation of Kynurenine Pathway dioxygenases by acute stress of mice by Dostal, Carlos R., Carson Sulzer, Megan, Kelley, Keith W., Freund, Gregory G., McCusker, Robert H.

“…Stressors activate the hypothalamic-pituitary-adrenal (HPA) axis and immune system eliciting changes in cognitive function, mood and anxiety. An important link…”
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The biobehavioral and neuroimmune impact of low-dose ionizing radiation by York, Jason M, Blevins, Neil A, Meling, Daryl D, Peterlin, Molly B, Gridley, Daila S, Cengel, Keith A, Freund, Gregory G

“…Abstract In the clinical setting, repeated exposures (10–30) to low-doses of ionizing radiation (⩽200 cGy), as seen in radiotherapy for cancer, causes fatigue…”
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Response of fish and macroinvertebrate bioassessment indices to water chemistry in a mined Appalachian watershed by Freund, Jason G, Petty, J Todd

“…Multimetric indices based on fish and benthic macroinvertebrate assemblages are commonly used to assess the biological integrity of aquatic ecosystems…”
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Morphological Characteristics of the Action of Cationic Peptide Warnerin on Regeneration of the Connective Tissue around Implanted Teflon Catheters in Mice under Conditions of Immunosuppression by Litvinov, V. V., Lemkina, L. M., Freund, G. G., Korobov, V. P.

“…Warnerin pretreatment of catheter segments subcutaneously implanted to mice under conditions of immunosuppression led to a significant increase in the number…”
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Acute calorie restriction modifies cognition and anxiety-like behavior in mice by regulating IL-1 β priming and activation within the brain by Towers, A.E, Oelschlager, M, Patel, J, Lawson, M, McCusker, R, Freund, G

“…IL-1 β is a central regulator of many biobehaviors including cognition and anxiety, however, how dietary interventions, such as acute calorie restriction…”
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Abstract # 1769 Exposure during fire-overhaul period demonstrates an increase in disease risk and immune dysregulation for first responders with impact being reduced using a transitional technique by Gainey, S.J, Towers, A, Oelschlager, M, Tir, V, J, Horn, G, Freund, G

“…Exposure during firefighting activities to combustion products (including carcinogens and asphyxiants) has been shown to increase immediate and long-term…”
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The implication of proinflammatory cytokines in type 2 diabetes by Guest, Christopher B, Park, Min J, Johnson, Daniel R, Freund, Gregory G

“…The incidence of type 2 diabetes (T2D) is rapidly expanding. Some of the more obvious pathologies associated with it include: defective glucose metabolism,…”
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Proinflammatory Cytokine Impairment of Insulin-Like Growth Factor I-Induced Protein Synthesis in Skeletal Muscle Myoblasts Requires Ceramide by Strle, Klemen, Broussard, Suzanne R, McCusker, Robert H, Shen, Wen-Hong, Johnson, Rodney W, Freund, Gregory G, Dantzer, Robert, Kelley, Keith W

“…GH and IGF-I control over 80% of postnatal growth. We recently established that TNFα impairs the ability of IGF-I to increase protein synthesis and promote…”
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Effect of Obesity on Acute Hemostatic Responses to Live-Fire Training Drills by Smith, Denise L., PhD, Horn, Gavin P., PhD, Petruzzello, Steven J., PhD, Freund, Gregory G., MD, Woods, Jeffrey A., PhD, Cook, Marc D., PhD, Goldstein, Eric, MS, Fernhall, Bo, PhD

“…The objective of this study was to evaluate the impact of obesity and firefighting activities on coagulation and fibrinolytic activity in relatively young,…”
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