Search Results - "FRESHWATER, Jason D"

Activation of p38 mitogen‐activated protein kinase in spinal microglia is a critical link in inflammation‐induced spinal pain processing by Svensson, Camilla I., Marsala, Martin, Westerlund, Anna, Calcutt, Nigel A., Campana, Wendy M., Freshwater, Jason D., Catalano, Rosanne, Feng, Ying, Protter, Andrew A., Scott, Brian, Yaksh, Tony L.

“…We examined the effect of p38 mitogen‐activated protein kinase (MAPK) inhibitors in models of nociception and correlated this effect with localization and…”
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Elevated Spinal Cyclooxygenase and Prostaglandin Release During Hyperalgesia in Diabetic Rats by FRESHWATER, Jason D, SVENSSON, Camilla I, MALMBERG, Annika B, CALCUTT, Nigel A

“…Elevated Spinal Cyclooxygenase and Prostaglandin Release During Hyperalgesia in Diabetic Rats Jason D. Freshwater 1 , Camilla I. Svensson 2 , Annika B…”
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Protection of sensory function and antihyperalgesic properties of a prosaposin-derived peptide in diabetic rats by CALCUTT, Nigel A, FRESHWATER, Jason D, O'BRIEN, John S

“…Short-term diabetes causes sensory disorders in rats ranging from thermal hypoalgesia to exaggerated behavioral responses to other sensory stimuli. As impaired…”
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Therapeutic efficacy of sonic hedgehog protein in experimental diabetic neuropathy by Calcutt, Nigel A, Allendoerfer, Karen L, Mizisin, Andrew P, Middlemas, Alicia, Freshwater, Jason D, Burgers, Monica, Ranciato, Rigel, Delcroix, Jean-Dominique, Taylor, Frederick R, Shapiro, Renee, Strauch, Kathy, Dudek, Henryk, Engber, Thomas M, Galdes, Alphonse, Rubin, Lee L, Tomlinson, David R

“…Hedgehog proteins modulate development and patterning of the embryonic nervous system. As expression of desert hedgehog and the hedgehog receptor, patched-1,…”
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Protection of sensory function in diabetic rats by Neotrofin by Calcutt, Nigel A., Freshwater, Jason D., Hauptmann, Nils, Taylor, Eve M., Mizisin, Andrew P.

“…We investigated the ability of Neotrofin, an agent that enhances endogenous nerve growth factor (NGF) levels, to prevent phenotypic, functional and structural…”
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Spinal mechanisms of hyperalgesia in experimental diabetes by Freshwater, Jason D

“…Peripheral neuropathy, the most common complication of diabetes, is often associated with painful symptoms, frequently unresponsive to conventional analgesic…”
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Polyol pathway and osmoregulation in JS1 Schwann cells grown in hyperglycemic and hyperosmotic conditions by Mizisin, A P, Li, L, Perello, M, Freshwater, J D, Kalichman, M W, Roux, L, Calcutt, N A

“…To test the osmoregulatory rules of Schwann cell aldose reductase (AR) and myo-inositol, JS1 Schwann cells were grown under control and hyperosmotic conditions…”
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