Search Results - "FRENZ, Theresa"

Type I interferon receptor signaling delays Kupffer cell replenishment during acute fulminant viral hepatitis by Borst, Katharina, Frenz, Theresa, Spanier, Julia, Tegtmeyer, Pia-Katharina, Chhatbar, Chintan, Skerra, Jennifer, Ghita, Luca, Namineni, Sukumar, Lienenklaus, Stefan, Köster, Mario, Heikenwaelder, Mathias, Sutter, Gerd, Kalinke, Ulrich

“…[Display omitted] •During acute viral hepatitis local IFN-I responses modulate liver inflammation.•IFNAR triggering of Kupffer cells protects against liver…”
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Systemic Virus Infections Differentially Modulate Cell Cycle State and Functionality of Long-Term Hematopoietic Stem Cells In Vivo by Hirche, Christoph, Frenz, Theresa, Haas, Simon F., Döring, Marius, Borst, Katharina, Tegtmeyer, Pia-K., Brizic, Ilija, Jordan, Stefan, Keyser, Kirsten, Chhatbar, Chintan, Pronk, Eline, Lin, Shuiping, Messerle, Martin, Jonjic, Stipan, Falk, Christine S., Trumpp, Andreas, Essers, Marieke A.G., Kalinke, Ulrich

“…Quiescent long-term hematopoietic stem cells (LT-HSCs) are efficiently activated by type I interferon (IFN-I). However, this effect remains poorly investigated…”
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CD4+ T cells in patients with chronic inflammatory rheumatic disorders show distinct levels of exhaustion by Frenz, Theresa, PhD, Grabski, Elena, PhD, Buschjäger, Daniela, MSc, Vaas, Lea A.I., PhD, Burgdorf, Nina, Schmidt, Reinhold E., MD, Witte, Torsten, MD, Kalinke, Ulrich, PhD

“…[...]expression of CD25 and the inhibitory T-cell coreceptors programmed cell death 1 (PD-1) and cytotoxic T lymphocyte-associated protein 4 (CTLA-4) was…”
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Characterization of the interferon-producing cell in mice infected with Listeria monocytogenes by Stockinger, Silvia, Kastner, Renate, Kernbauer, Elisabeth, Pilz, Andreas, Westermayer, Sandra, Reutterer, Benjamin, Soulat, Didier, Stengl, Gabriele, Vogl, Claus, Frenz, Theresa, Waibler, Zoe, Taniguchi, Tadatsugu, Rülicke, Thomas, Kalinke, Ulrich, Müller, Mathias, Decker, Thomas

“…Production of type I interferons (IFN-I, mainly IFNalpha and IFNbeta) is a hallmark of innate immune responses to all classes of pathogens. When viral…”
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Vaccinia Virus-Mediated Inhibition of Type I Interferon Responses Is a Multifactorial Process Involving the Soluble Type I Interferon Receptor B18 and Intracellular Components by Waibler, Zoe, Anzaghe, Martina, Frenz, Theresa, Schwantes, Astrid, Pöhlmann, Christopher, Ludwig, Holger, Palomo-Otero, Marcos, Alcamí, Antonio, Sutter, Gerd, Kalinke, Ulrich

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Critical role of perforin-dependent CD8+ T cell immunity for rapid protective vaccination in a murine model for human smallpox by Kremer, Melanie, Suezer, Yasemin, Volz, Asisa, Frenz, Theresa, Majzoub, Monir, Hanschmann, Kay-Martin, Lehmann, Michael H, Kalinke, Ulrich, Sutter, Gerd

“…Vaccination is highly effective in preventing various infectious diseases, whereas the constant threat of new emerging pathogens necessitates the development…”
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Thogoto Virus Infection Induces Sustained Type I Interferon Responses That Depend on RIG-I-Like Helicase Signaling of Conventional Dendritic Cells by KOCHS, Georg, BAUER, Stefanie, VOGT, Carola, FRENZ, Theresa, TSCHOPP, Jürg, KALINKE, Ulrich, WAIBLER, Zoe

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Antigen presenting cell-selective drug delivery by glycan-decorated nanocarriers by Frenz, Theresa, Grabski, Elena, Durán, Verónica, Hozsa, Constantin, Stępczyńska, Anna, Furch, Marcus, Gieseler, Robert K., Kalinke, Ulrich

“…[Display omitted] •APC-selective drug delivery suitable for new therapeutic strategies.•Liposomes can deliver decent quantities of defined…”
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Independent of plasmacytoid dendritic cell (pDC) infection, pDC triggered by virus-infected cells mount enhanced type I IFN responses of different composition as opposed to pDC stimulated with free virus by Frenz, Theresa, Graalmann, Lukas, Detje, Claudia N, Döring, Marius, Grabski, Elena, Scheu, Stefanie, Kalinke, Ulrich

“…Upon treatment with vesicular stomatitis virus (VSV) particles, plasmacytoid dendritic cells (pDC) are triggered to mount substantial type I IFN responses,…”
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Immunogenic cell death of dendritic cells following modified vaccinia virus Ankara infection enhances CD8+ T cell proliferation by Tappe, Kim A., Budida, Ramachandramouli, Stankov, Metodi V., Frenz, Theresa, R. Shah, Harshit, Volz, Asisa, Sutter, Gerd, Kalinke, Ulrich, Behrens, Georg M. N.

“…“Immunogenic cell death” (ICD) is associated with the emission of so‐called damage‐associated molecular patterns (DAMPs) which trigger the immune response…”
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M27 expressed by cytomegalovirus counteracts effective type I interferon induction of myeloid cells but not of plasmacytoid dendritic cells by Döring, Marius, Lessin, Irina, Frenz, Theresa, Spanier, Julia, Kessler, Annett, Tegtmeyer, Pia, Dağ, Franziska, Thiel, Nadine, Trilling, Mirko, Lienenklaus, Stefan, Weiss, Siegfried, Scheu, Stefanie, Messerle, Martin, Cicin-Sain, Luka, Hengel, Hartmut, Kalinke, Ulrich

“…In healthy individuals, the functional immune system effectively confines human cytomegalovirus (CMV) replication, while viral immune evasion and persistence…”
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12: Local IFN-I responses orchestrate cytokine responses and confer protection upon vaccinia virus infection by Borst, Katharina, Frenz, Theresa, Lienenklaus, Stefan, Köster, Mario, Namineni, Sukumar, Heikenwälder, Mathias, Sutter, Gerd, Kalinke, Ulrich

“…Viruses express a wide range of immune evasion proteins to modulate host immunity. The DNA-encoded poxvirus vaccinia virus (VACV) carries IFN-I inhibitors of…”
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12 by Borst, Katharina, Frenz, Theresa, Lienenklaus, Stefan, Köster, Mario, Namineni, Sukumar, Heikenwälder, Mathias, Sutter, Gerd, Kalinke, Ulrich

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Virus infections differentially modulate the cell cycle state and functionality of dormant long-term hematopoietic stem cells in vivo by Hirche, Christoph, Frenz, Theresa, Haas, Simon, Brizic, Ilija, Keyser, Kirsten, Döring, Marius, Halle, Stephan, Förster, Reinhold, Jonjic, Stipan, Messerle, Martin, Essers, Marieke, Trumpp, Andreas, Kalinke, Ulrich

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ID: 237: In virus-induced hepatitis local IFN-I responses modulate myeloid suppressor cell infiltration by Borst, Katharina, Frenz, Theresa, Spanier, Julia, Tegtmeyer, Pia-Katharina, Chhatbar, Chintan, Namineni, Sukumar, Lienenklaus, Stefan, Köster, Mario, Heikenwälder, Mathias, Sutter, Gerd, Kalinke, Ulrich

“…Most viruses developed mechanisms that inhibit the induction or the function of type I interferon (IFN-I). Vaccinia virus (VACV), a large DNA-encoded poxvirus,…”
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ID: 237 by Borst, Katharina, Frenz, Theresa, Spanier, Julia, Tegtmeyer, Pia-Katharina, Chhatbar, Chintan, Namineni, Sukumar, Lienenklaus, Stefan, Köster, Mario, Heikenwälder, Mathias, Sutter, Gerd, Kalinke, Ulrich

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Concomitant type I IFN receptor-triggering of T cells and of DC is required to promote maximal modified vaccinia virus Ankara-induced T-cell expansion by Frenz, Theresa, Waibler, Zoe, Hofmann, Janin, Hamdorf, Matthias, Lantermann, Markus, Reizis, Boris, Tovey, Michaël G, Aichele, Peter, Sutter, Gerd, Kalinke, Ulrich

“…Virus-induced expansion of CD8⁺ T cells may be promoted by type I IFN receptor (IFNAR)-triggering of T cells, depending on the pathogen tested. We studied…”
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Building a zoo of mice for genetic analyses: A comprehensive protocol for the rapid generation of BAC transgenic mice by Johansson, Torbjörn, Broll, Ilja, Frenz, Theresa, Hemmers, Saskia, Becher, Burkhard, Zeilhofer, Hanns Ulrich, Buch, Thorsten

“…Transgenic mice are highly valuable tools for biological research as they allow cell type–specific expression of functionally instrumental genes. In this…”
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Characterization of the Interferon-Producing Cell in Mice Infected with Listeria monocytogenes: e1000355 by Stockinger, Silvia, Kastner, Renate, Kernbauer, Elisabeth, Pilz, Andreas, Westermayer, Sandra, Reutterer, Benjamin, Soulat, Didier, Stengl, Gabriele, Vogl, Claus, Frenz, Theresa, Waibler, Zoe, Taniguchi, Tadatsugu, Rülicke, Thomas, Kalinke, Ulrich, Müller, Mathias, Decker, Thomas

“…Production of type I interferons (IFN-I, mainly IFNα and IFNβ) is a hallmark of innate immune responses to all classes of pathogens. When viral infection…”
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