Search Results - "FRENCH, S. W"
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Testosterone Replacement Ameliorates Nonalcoholic Fatty Liver Disease in Castrated Male Rats
Published in Endocrinology (Philadelphia) (01-02-2014)“…Nonalcoholic fatty liver disease is common in developed countries and is associated with obesity, metabolic syndrome, and type 2 diabetes. T deficiency is a…”
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2
Whole-mantle radially anisotropic shear velocity structure from spectral-element waveform tomography
Published in Geophysical journal international (01-12-2014)“…The radially anisotropic shear velocity structure of the Earth's mantle provides a critical window on the interior dynamics of the planet, with isotropic…”
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3
Combination therapy with iron chelation and vancomycin in treating murine staphylococcemia
Published in European journal of clinical microbiology & infectious diseases (01-05-2014)“…Iron acquisition is a virulence factor for Staphylococcus aureus . We assessed the efficacy of the iron chelator, deferasirox (Def), alone or in combination…”
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4
Crustal structure beneath the Florida‐to‐Edmonton broadband seismometer array
Published in Geophysical research letters (01-04-2009)“…Ps receiver functions were stacked to determine crustal thickness and Vp/Vs ratios for the 28 stations of the Florida‐to‐Edmonton Broadband Seismometer Array…”
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5
Over expression of proteins that alter the intracellular signaling pathways in the cytoplasm of the liver cells forming Mallory-Denk bodies
Published in Experimental and molecular pathology (01-02-2017)“…In this study, liver biopsy sections fixed in formalin and embedded in paraffin (FFPE) from patients with alcoholic hepatitis (AH) were used. The results…”
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Molecular events in hepatic preneoplasia: A review
Published in Experimental and molecular pathology (01-04-2010)Get full text
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FAT10 knock out mice livers fail to develop Mallory–Denk bodies in the DDC mouse model
Published in Experimental and molecular pathology (01-12-2012)“…Mallory–Denk bodies (MDBs) are aggresomes composed of undigested ubiqutinated short lived proteins which have accumulated because of a decrease in the rate of…”
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Digital quantitation of HCC-associated stem cell markers and protein quality control factors using tissue arrays of human liver sections
Published in Experimental and molecular pathology (01-12-2014)“…The most common type of liver cancer, hepatocellular carcinoma (HCC), affects over 500,000 people in the world. In the present study, liver tumor resections…”
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The mechanisms of Mallory–Denk body formation are similar to the formation of aggresomes in Alzheimer's disease and other neurodegenerative disorders
Published in Experimental and molecular pathology (01-06-2016)“…There is a possibility that the aggresomes that form in the brain in neurodegenerative diseases like Alzheimer's disease (AD) and in the liver where aggresomes…”
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10
Changes in IL12A methylation pattern in livers from mice fed DDC
Published in Experimental and molecular pathology (01-04-2012)“…Mallory–Denk body (MDB) formation is a component of alcoholic and non alcoholic hepatitis. Proteins of the TLR pathway were shown to be involved in the…”
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Mallory–Denk bodies form when EZH2/H3K27me3 fails to methylate DNA in the nuclei of human and mice liver cells
Published in Experimental and molecular pathology (01-06-2012)“…EZH2/H3K27me3 and polycomb group complex (PcG) play a major role in regulating global gene expression including tumor suppressor genes. EZH2 is linked to cell…”
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Upregulation of autophagy components in alcoholic hepatitis and nonalcoholic steatohepatitis
Published in Experimental and molecular pathology (01-08-2016)“…There are many homeostatic mechanisms for coping with stress conditions in cells, including autophagy. In many studies autophagy, as an intracellular pathway…”
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The role of innate immunity in the pathogenesis of preneoplasia in drug-induced chronic hepatitis based on a mouse model
Published in Experimental and molecular pathology (01-12-2011)“…Innate immunity factors such as conversion of the 26S proteasome to form the immunoproteasome and the Toll-like receptor signaling pathways are activated in…”
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The cyclic pattern of blood alcohol levels during continuous ethanol feeding in rats The effect of feeding S-adenosylmethionine
Published in Experimental and molecular pathology (01-06-2010)“…S-adenosylmethionine (SAMe), the major methyl donor for DNA and histone methylation was fed with ethanol for 1month in order to modify the effects of ethanol…”
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Effect of chronic ethanol feeding on lipid peroxidation and protein oxidation in relation to liver pathology
Published in Hepatology (Baltimore, Md.) (01-02-1997)“…Liver lipid peroxidation, nonheme iron, antioxidants, and protein oxidation were investigated in experimental alcohol‐induced liver disease in the rat. Wistar…”
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Global DNA methylation profiling reveals silencing of a secreted form of Epha7 in mouse and human germinal center B-cell lymphomas
Published in Oncogene (21-06-2007)“…Most human lymphomas originate from transformed germinal center (GC) B lymphocytes. While activating mutations and translocations of MYC, BCL2 and BCL6 promote…”
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Betaine feeding prevents the blood alcohol cycle in rats fed alcohol continuously for 1 month using the rat intragastric tube feeding model
Published in Experimental and molecular pathology (01-10-2011)“…Blood alcohol levels (BAL) cycle up and down over a 7–8 day period when ethanol is fed continuously for one month in the intragastric tube feeding rat model…”
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How to prevent alcoholic liver disease
Published in Experimental and molecular pathology (01-04-2015)“…Betaine supplements of alcoholic beverages are proposed to prevent the development of alcoholic liver disease in patients that abuse alcohol. This…”
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The role of stem cells/progenitor cells in liver carcinogenesis in glycine N-methyltransferase deficient mice
Published in Experimental and molecular pathology (01-04-2010)“…Regeneration of the liver is inhibited as a result of a sustained increase in S-adenosylmethionine levels in glycine N-methyltransferase (GNMT)−/− mice. This…”
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The effect of propranolol on gene expression during the blood alcohol cycle of rats fed ethanol intragastrically
Published in Experimental and molecular pathology (01-02-2010)“…Propranolol, a beta adrenergic blocker prevents the blood alcohol (BAL) cycle in rats fed ethanol intragastrically at a constant rate by preventing the cyclic…”
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