Search Results - "FREDERIKSEN, Shirley M"

A multilevel intervention to increase community hospital use of alteplase for acute stroke (INSTINCT): a cluster-randomised controlled trial by Scott, Phillip A, Dr, Meurer, William J, MD, Frederiksen, Shirley M, MS, Kalbfleisch, John D, Prof, Xu, Zhenzhen, PhD, Haan, Mary N, Prof, Silbergleit, Robert, MD, Morgenstern, Lewis B, Prof

“…Summary Background Use of alteplase improves outcome in some patients with stroke. Several types of barrier frequently prevent its use. We assessed whether a…”
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Provider perceptions of barriers to the emergency use of tPA for acute ischemic stroke: a qualitative study by Meurer, William J, Majersik, Jennifer J, Frederiksen, Shirley M, Kade, Allison M, Sandretto, Annette M, Scott, Phillip A

“…Only 1-3% of ischemic stroke patients receive thrombolytic therapy. Provider barriers to adhering with guidelines recommending tPA delivery in acute stroke are…”
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Prevention of emergency physician migratory contamination in a cluster randomized trial to increase tissue plasminogen activator use in stroke (the INSTINCT trial) by Weston, Victoria C., MD, Meurer, William J., MD, Frederiksen, Shirley M., MS, RN, Fox, Allison K., BA, Scott, Phillip A., MD

“…Abstract Objectives Cluster randomized trials (CRTs) are increasingly used to evaluate quality improvement interventions aimed at health care providers. In…”
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Protocol Deviations before and after Treatment with Intravenous Tissue Plasminogen Activator in Community Hospitals by Adelman, Eric E., MD, Scott, Phillip A., MD, Skolarus, Lesli E., MD, Fox, Allison K., MS, Frederiksen, Shirley M., MS, Meurer, William J., MD

“…Background Protocol deviations before and after tissue plasminogen activator (tPA) treatment for ischemic stroke are common. It is unclear if patient or…”
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Attitudes and opinions regarding confirmatory adaptive clinical trials: a mixed methods analysis from the Adaptive Designs Accelerating Promising Trials into Treatments (ADAPT-IT) project by Meurer, William J, Legocki, Laurie, Mawocha, Samkeliso, Frederiksen, Shirley M, Guetterman, Timothy C, Barsan, William, Lewis, Roger, Berry, Donald, Fetters, Michael

“…Adaptive designs have been increasingly used in the pharmaceutical and device industries, but adoption within the academic setting has been less widespread -…”
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Prospective Performance Assessment of an Out-of-Hospital Protocol for Selective Spine Immobilization Using Clinical Spine Clearance Criteria by Domeier, Robert M., Frederiksen, Shirley M., Welch, Kathy

“…We determine whether the use of an emergency medical services (EMS) protocol for selective spine immobilization would result in appropriate immobilization…”
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Attitudes and beliefs of Michigan emergency physicians toward tissue plasminogen activator use in stroke: baseline survey results from the INcreasing Stroke Treatment through INteractive behavioral Change Tactic (INSTINCT) trial hospitals by Scott, Phillip A, Xu, Zhenzhen, Meurer, William J, Frederiksen, Shirley M, Haan, Mary N, Westfall, Michael W, Kothari, Sandip U, Morgenstern, Lewis B, Kalbfleisch, John D

“…The objective of this study was to determine the baseline proportion of emergency physicians with favorable attitudes and beliefs toward intravenous tissue…”
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Antihypertensive Treatment Prolongs Tissue Plasminogen Activator Door-to-Treatment Time: Secondary Analysis of the INSTINCT Trial by SKOLARUS, Lesli E, SCOTT, Phillip A, BURKE, James F, ADELMAN, Eric E, FREDERIKSEN, Shirley M, KADE, Allison M, KALBFLEISCH, Jack D, FORD, Andria L, MEURER, William J

“…Identifying modifiable tissue plasminogen activator treatment delays may improve stroke outcomes. We hypothesized that prethrombolytic antihypertensive…”
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Does Preexisting Antiplatelet Treatment Influence Postthrombolysis Intracranial Hemorrhage in Community‐treated Ischemic Stroke Patients? An Observational Study by Meurer, William J., Kwok, Heemun, Skolarus, Lesli E., Adelman, Eric E., Kade, Allison M., Kalbfleisch, Jack, Frederiksen, Shirley M., Scott, Phillip A., O'Neil, Brian J.

“…Objectives Intracranial hemorrhage (ICH) after acute stroke thrombolysis is associated with poor outcomes. Previous investigations of the relationship between…”
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Lack of association between pretreatment neurology consultation and subsequent protocol deviation in tissue plasminogen activator-treated patients with stroke by Meurer, William J, Caveney, Angela F, Lo, Alex, Zhang, Lingling, Frederiksen, Shirley M, Sandretto, Annette M, Silbergleit, Robert, Scott, Phillip A

“…We evaluated the hypothesis that consultation with neurology would be associated with fewer protocol deviations in tissue plasminogen activator-treated…”
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Safety of Intravenous Thrombolytic Use in Four Emergency Departments Without Acute Stroke Teams by Scott, Phillip A., Frederiksen, Shirley M., Kalbfleisch, John D., Xu, Zhenzhen, Meurer, William J., Caveney, Angela F., Sandretto, Annette, Holden, Ann B., Haan, Mary N., Hoeffner, Ellen G., Ansari, Sameer A., Lambert, David P., Jaggi, Michael, Barsan, William G., Silbergleit, Robert

“…Objectives:  The objective was to evaluate safety of intravenous (IV) tissue plasminogen activator (tPA) delivered without dedicated thrombolytic stroke teams…”
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Lack of association between hyperglycaemia at arrival and clinical outcomes in acute stroke patients treated with tissue plasminogen activator by Meurer, William J., Scott, Phillip A., Caveney, Angela F., Majersik, Jennifer J., Frederiksen, Shirley M., Sandretto, Annette, Holden, Ann B., Silbergleit, Robert

“…Rationale Hyperglycaemia is associated with adverse outcomes in some studies of acute ischaemic stroke. Aims We hypothesised that in thrombolytic-treated…”
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Prevalence of atrial fibrillation and antithrombotic prophylaxis in emergency department patients by SCOTT, Phillip A, PANCIOLI, Arthur M, DAVIS, Lisa A, FREDERIKSEN, Shirley M, ECKMAN, John

“…The emergency department (ED), as the point of first medical contact for many complaints referable to atrial fibrillation (AF) and a common source of primary…”
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The impact of emergency physician turnover on planning for prospective clinical trials by Meurer, William J, Sozener, Cemal B, Xu, Zhenzhen, Frederiksen, Shirley M, Kade, Allison M, Olgren, Michael, Vieder, Sanford J, Kalbfleish, John D, Scott, Phillip A

“…Emergency physician (EP) turnover is a significant issue that can have strong economic impact on hospital systems, as well as implications on research efforts…”
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The feasibility of pain assessment in the prehospital setting by McLean, Samuel A, Domeier, Robert M, DeVore, Heather K, Hill, Elizabeth M, Maio, Ronald F, Frederiksen, Shirley M

“…To determine the feasibility of prehospital pain measurement among patients 13 years of age or older using a verbal and numeric rating scale and to assess the…”
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Qualitative Data Collection and Analysis Methods: The INSTINCT Trial by Meurer, William J., Frederiksen, Shirley M., Majersik, Jennifer J., Zhang, Lingling, Sandretto, Annette, Scott, Phillip A.

“…Patient care practices often lag behind current scientific evidence and professional guidelines. The failure of such knowledge translation (KT) efforts may…”
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Prevention of EP Migratory Contamination in a Cluster Randomized Trial to Increase tPA Use in Stroke (The INSTINCT Trial) by Weston, Victoria C., Meurer, William J., Frederiksen, Shirley M., Fox, Allison K., Scott, Phillip A.

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Protocol deviations before and after IV tPA in community hospitals by Adelman, Eric E., Scott, Phillip A., Skolarus, Lesli E., Fox, Allison K., Frederiksen, Shirley M., Meurer, William J.

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Abstract 174: Economic Benefit of an Educational Intervention to Improve tPA Use in Community Hospitals: Secondary Analysis of the INSTINCT Trial by Sozener, Cemal B, Hutton, David W, Meurer, William J, Frederiksen, Shirley M, Kade, Allison M, Scott, Phillip A

“…Abstract only Introduction: Prior work demonstrates substantial economic benefit from tPA use. We hypothesized a T2 knowledge translation (KT) program to…”
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Anti-hypertensive treatment prolongs tPA door-to-treatment time: Secondary analysis of the INSTINCT trial by Skolarus, Lesli E., Scott, Phillip A., Burke, James F., Adelman, Eric E., Frederiksen, Shirley M., Kade, Allison M., Kalbfleisch, Jack D., Ford, Andria L., Meurer, William J.

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