Search Results - "FREDERICH, Robert C"

Long-term weight-loss maintenance : a meta-analysis of US studies by ANDERSON, James W, KONZ, Elizabeth C, FREDERICH, Robert C, WOOD, Constance L

“…Current perception is that participants of a structured weight-loss program regain all of their weight loss within 5 y. The objective was to examine the…”
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Leptin levels reflect body lipid content in mice: Evidence for diet-induced resistance to leptin action by Frederich, Robert C, Hamann, Andreas, Anderson, Stephen, Löllmann, Bettina, Lowell, Bradford B, Flier, Jeffrey S

“…The regulation of body weight and composition involves input from genes and the environment, demonstrated, for example, by the variable susceptibility of…”
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Melanin-concentrating hormone: a functional melanocortin antagonist in the hypothalamus by Ludwig, D S, Mountjoy, K G, Tatro, J B, Gillette, J A, Frederich, R C, Flier, J S, Maratos-Flier, E

“…Melanin-concentrating hormone (MCH) and alpha-melanocyte-stimulating hormone (alpha-MSH) demonstrate opposite actions on skin coloration in teleost fish. Both…”
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Ertugliflozin and hospitalization for heart failure across the spectrum of pre-trial ejection fraction: post-hoc analyses of the VERTIS CV trial by Pandey, Ambarish, Kolkailah, Ahmed A, Cosentino, Francesco, Cannon, Christopher P, Frederich, Robert C, Cherney, David Z I, Dagogo-Jack, Samuel, Pratley, Richard E, Cater, Nilo B, Gantz, Ira, Mancuso, James P, McGuire, Darren K

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Multiple cytokines and acute inflammation raise mouse leptin levels: potential role in inflammatory anorexia by Sarraf, P, Frederich, R C, Turner, E M, Ma, G, Jaskowiak, N T, Rivet, 3rd, D J, Flier, J S, Lowell, B B, Fraker, D L, Alexander, H R

“…Several inflammatory cytokines, most notably tumor necrosis factor (TNF) and IL-1, induce anorexia and loss of lean body mass, common manifestations of acute…”
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Behavioral and Subjective Effects of d-Amphetamine and Modafinil in Healthy Adults by Makris, Angela P, Rush, Craig R, Frederich, Robert C, Taylor, Alisia C, Kelly, Thomas H

“…Modafinil is indicated for the management of excessive daytime sleepiness; however, recent studies have examined a broad range of potential uses. Given that…”
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Immunohistochemical Localization of Leptin and Uncoupling Protein in White and Brown Adipose Tissue by Cinti, Saverio, Frederich, Robert C., Zingaretti, M. Cristina, De Matteis, Rita, Flier, Jeffrey S., Lowell, Bradford B.

“…Abstract Leptin is synthesized exclusively by adipocytes and acts on the hypothalamus to regulate energy balance. Previous messenger RNA expression studies…”
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Wake-promoting agents with different mechanisms of action: comparison of effects of modafinil and amphetamine on food intake and cardiovascular activity by Makris, Angela P, Rush, Craig R, Frederich, Robert C, Kelly, Thomas H

“…Despite efforts to achieve a desirable weight, two-thirds of the population has an elevated body weight. Medications are useful in supporting weight loss, but…”
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Tissue-Specific Nutritional Regulation of Angiotensinogen in Adipose Tissue by Frederich, Robert C, Kahn, Barbara B, Peach, Michael J, Flier, Jeffrey S

“…Recent studies have found that angiotensinogen is expressed in white and brown fat pads, and adipocytes have been implicated as a primary source of…”
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Decreased food intake rather than zinc deficiency is associated with changes in plasma leptin, metabolic rate, and activity levels in zinc deficient rats by Gaetke, Lisa M., Frederich, Robert C., Oz, Helieh S., McClain, Craig J.

“…This study investigated the hypothesis that the reduced food intake and poor weight gain in zinc deficient rats is due to: increased plasma leptin…”
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Severe leptin resistance in brown fat-deficient uncoupling protein promoter-driven diphtheria toxin A mice despite suppression of hypothalamic neuropeptide Y and circulating corticosterone concentrations by MANTZOROS, C. S, FREDERICH, R. C, QU, D, LOWELL, B. B, MARATOS-FLIER, E, FLIER, J. S

“…Brown adipose tissue (BAT) has the capacity for uncoupled mitochondrial respiration and is proposed to be a key site for regulating energy expenditure in…”
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The leptin defense against wasting is abolished in the IL-2-deficient mouse model of inflammatory bowel disease by Gaetke, Lisa M, Oz, Helieh S, de Villiers, Willem J S, Varilek, Gary W, Frederich, Robert C

“…Anorexia is a major complication of inflammatory bowel disease (IBD). We postulated that chronic intestinal inflammation with increased proinflammatory…”
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Targeted Disruption of the β3-Adrenergic Receptor Gene by Susulic, Vedrana S., Frederich, Robert C., Lawitts, Joel, Tozzo, Effie, Kahn, Barbara B., Harper, Mary-Ellen, Himms-Hagen, Jean, Flier, Jeffrey S., Lowell, Bradford B.

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Activation of β3 adrenergic receptors suppresses leptin expression and mediates a leptin-independent inhibition of food intake in mice by MANTZOROS, C. S, QU, D, FREDERICH, R. C, SUSULIC, V. S, LOWELL, B. B, MARATOS-FLIER, E, FLIER, J. S

“…To examine potential interactions between leptin and the β3 adrenergic system in the regulation of food intake, we determined the effects of treatment with a…”
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Anti-TNF-α Antibody Normalizes Serum Leptin in IL-2 Deficient Mice by Gaetke, Lisa M, Oz, Helieh S, Frederich, Robert C, McClain, Craig J

“…Objective: A recent study reports that the interleukin-2 deficient (IL-2−/−) mouse model of autoimmune and inflammatory bowel disease (IBD) with elevated…”
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Expression of ob mRNA and its encoded protein in rodents. Impact of nutrition and obesity by Frederich, R C, Löllmann, B, Hamann, A, Napolitano-Rosen, A, Kahn, B B, Lowell, B B, Flier, J S

“…The mutant gene responsible for obesity in the ob/ob mouse was recently identified by positional cloning (Zhang Y., R. Proenca, M. Maffel, M. Barone, L…”
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Long-term weight-loss maintenance: a meta-analysis of US studies123 by Anderson, James W, Konz, Elizabeth C, Frederich, Robert C, Wood, Constance L

“…Current perception is that participants of a structured weight-loss program regain all of their weight loss within 5 y. The objective was to examine the…”
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Metabolic effects of insulin and insulin-like growth factor-I in endotoxemic rats during total parenteral nutrition feeding by Ling, Pei Ra, Lydon, Erin, Zhensheng, Qu, Frederich, Robert C., Bistrian, Bruce R.

“…The effects of insulin and insulin-like growth factor-I (IGF-I) on protein, energy, and glucose metabolism were examined in endotoxemic rats receiving total…”
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Activation of beta3 adrenergic receptors suppresses leptin expression and mediates a leptin-independent inhibition of food intake in mice by Mantzoros, Christos S, Qu, Daqing, Frederich, Robert C, Susulic, Vedrana S

“…To examine potential interactions between leptin and the beta3 adrenergic system in the regulation of food intake, we determined the effects of treatment with…”
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Immunohistochemical Localization of Leptin and Uncoupling Protein in White and Brown Adipose Tissue 1 by Cinti, Saverio, Frederich, Robert C., Zingaretti, M. Cristina, De Matteis, Rita, Flier, Jeffrey S., Lowell, Bradford B.

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