Search Results - "FRANZEN, A"

Urinary Exosomes: The Potential for Biomarker Utility, Intercellular Signaling and Therapeutics in Urological Malignancy by Franzen, Carrie A, Blackwell, Robert H, Foreman, Kimberly E, Kuo, Paul C, Flanigan, Robert C, Gupta, Gopal N

“…Purpose Exosomes are small secreted vesicles that contain proteins, mRNA and miRNA with the potential to alter signaling pathways in recipient cells…”
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Characterization of Uptake and Internalization of Exosomes by Bladder Cancer Cells by Franzen, Carrie A., Simms, Patricia E., Van Huis, Adam F., Foreman, Kimberly E., Kuo, Paul C., Gupta, Gopal N.

“…Bladder tumors represent a special therapeutic challenge as they have a high recurrence rate requiring repeated interventions and may progress to invasive or…”
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Osteopontin mediates an MZF1–TGF-β1-dependent transformation of mesenchymal stem cells into cancer-associated fibroblasts in breast cancer by Weber, C E, Kothari, A N, Wai, P Y, Li, N Y, Driver, J, Zapf, M A C, Franzen, C A, Gupta, G N, Osipo, C, Zlobin, A, Syn, W K, Zhang, J, Kuo, P C, Mi, Z

“…Interactions between tumor cells and cancer-associated fibroblasts (CAFs) in the tumor microenvironment significantly influence cancer growth and metastasis…”
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The rising incidence of parotid metastases: our experience from four decades of parotid gland surgery by Franzen, A, Buchali, A, Lieder, A

“…Secondary neoplasia in the parotid gland is increasingly frequent. We examined outcomes from 40 years of parotid surgery to analyse patterns for metastasis,…”
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Management of primary malignant lymphoma of the parotid gland in a series of seven hundred and forty‐five patients by Lieder, A., Franzen, A.

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Urothelial cells undergo epithelial-to-mesenchymal transition after exposure to muscle invasive bladder cancer exosomes by Franzen, C A, Blackwell, R H, Todorovic, V, Greco, K A, Foreman, K E, Flanigan, R C, Kuo, P C, Gupta, G N

“…Bladder cancer, the fourth most common noncutaneous malignancy in the United States, is characterized by high recurrence rate, with a subset of these cancers…”
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Adverse outcome pathway (AOP): α2u-globulin nephropathy and kidney tumors in male rats by Goyak, Katy O., Sarang, Satinder S., Franzen, A., Borghoff, Susan J., Ryman-Rasmussen, Jessica P.

“…The National Research Council's vision of using adverse outcome pathways (AOPs) as a framework to assist with toxicity assessment for regulatory requirements…”
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Prognostic and predictive methylation biomarkers in HNSCC : Epigenomic diagnostics for head and neck squamous cell carcinoma (HNSCC) by Franzen, A, Bootz, F, Dietrich, D

“…Prognostic and predictive biomarkers for personalized treatment management in head and neck squamous cell carcinoma (HNSCC) are of great clinical interest. DNA…”
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Measuring Distress Risk: The Effect of R&D Intensity by FRANZEN, LAUREL A., RODGERS, KIMBERLY J., SIMIN, TIMOTHY T.

“…Because of upward trends in research and development activity, accounting measures of financial distress have become less accurate. We document that (1) higher…”
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Ibrutinib and venetoclax target distinct subpopulations of CLL cells: implication for residual disease eradication by Lu, Pin, Wang, Shengchun, Franzen, Carrie A., Venkataraman, Girish, McClure, Rebecca, Li, Lei, Wu, Wenjun, Niu, Nifang, Sukhanova, Madina, Pei, Jianming, Baldwin, Donald A., Nejati, Reza, Wasik, Mariusz A., Khan, Nadia, Tu, Yifan, Gao, Juehua, Chen, Yihua, Ma, Shuo, Larson, Richard A., Wang, Y. Lynn

“…Ibrutinib inhibits Bruton tyrosine kinase while venetoclax is a specific inhibitor of the anti-apoptotic protein BCL2. Both drugs are highly effective as…”
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Testing Hypotheses for the Success of Different Conservation Strategies by BROOKS, JEREMY S., FRANZEN, MARGARET A., HOLMES, CHRISTOPHER M., GROTE, MARK N., MULDER, MONIQUE BORGERHOFF

“…Evaluations of the success of different conservation strategies are still in their infancy. We used four different measures of project outcomes-ecological,…”
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Response to "letter concerning: Clewell (2019) incorporation of in vitro metabolism data and physiologically based pharmacokinetic modeling in a risk assessment for chloroprene." (UIHT-2020-0053) by Clewell, H. J., Campbell, J. L., Van Landingham, C., Franzen, A., Yoon, M., Dodd, D. E., Andersen, M. E., Gentry, P. R.

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Inhibition of HIF-1 alpha and VEGF expression by the chemopreventive bioflavonoid apigenin is accompanied by Akt inhibition in human prostate carcinoma PC3-M cells by Mirzoeva, Salida, Kim, Nam Deuk, Chiu, Karen, Franzen, Carrie A., Bergan, Raymond C., Pelling, Jill C.

“…Progression of cancer leads to hypoxic solid tumors that mount specific cell signaling responses to low oxygen conditions. An important objective of…”
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Seeing Eye to Eye? Comparing Faculty and Student Perceptions of Biomolecular Visualization Assessments by Beckham, Josh T., Dries, Daniel R., Hall, Bonnie L., Mitton-Fry, Rachel M., Engelman, Shelly, Burch, Charmita, Acevedo, Roderico, Mertz, Pamela S., Vardar-Ulu, Didem, Agrawal, Swati, Fox, Kristin M., Austin, Shane, Franzen, Margaret A., Jakubowski, Henry V., Novak, Walter R. P., Roberts, Rebecca, Roca, Alberto I., Procko, Kristen

“…While visual literacy has been identified as a foundational skill in life science education, there are many challenges in teaching and assessing biomolecular…”
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Tonsil surgery in Brandenburg-trends between 2013 and 2017 by Franzen, A M, Jungehülsing, M, Berthold, U, Rudolf, J, Herzog, M, Heinze, N, Didczuneit-Sandhop, B, Kanzock, J, Schrom, T

“…The frequency of tonsil surgery in Brandenburg (BB) during the period from 2013 to 2017 is analyzed. Causes and possible consequences of the trends are…”
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The desmosomal armadillo protein plakoglobin regulates prostate cancer cell adhesion and motility through vitronectin-dependent Src signaling by Franzen, Carrie A, Todorović, Viktor, Desai, Bhushan V, Mirzoeva, Salida, Yang, Ximing J, Green, Kathleen J, Pelling, Jill C

“…Plakoglobin (PG) is an armadillo protein that associates with both classic and desmosomal cadherins, but is primarily concentrated in mature desmosomes in…”
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Inhibition of B-cell receptor signaling disrupts cell adhesion in mantle cell lymphoma via RAC2 by Wu, Wenjun, Wang, Weige, Franzen, Carrie A., Guo, Hui, Lee, Jimmy, Li, Yan, Sukhanova, Madina, Sheng, Dong, Venkataraman, Girish, Ming, Mei, Lu, Pin, Gao, Anhui, Xia, Chunmei, Li, Jia, Zhang, Liang Leo, Jiang, Vivian Changying, Wang, Michael L., Andrade, Jorge, Zhou, Xiaoyan, Wang, Y. Lynn

“…Inhibition of the B-cell receptor (BCR) signaling pathway is highly effective in B-cell neoplasia through Bruton tyrosine kinase inhibition by ibrutinib…”
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Matrix Protein CCN1 Is Critical for Prostate Carcinoma Cell Proliferation and TRAIL-Induced Apoptosis by Franzen, Carrie A, Chen, Chih-Chiun, Todorović, Viktor, Juric, Vladislava, Monzon, Ricardo I, Lau, Lester F

“…Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) plays an important role in immune surveillance and preferentially induces apoptosis in cancer…”
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629: Expression and role of the embryonic protein SOX2 in head and neck squamous cell carcinoma by Schröck, A, Bode, M, Franzen, A, Heasley, L, Lengerke, C, Perner, S, Queisser, A

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The chemopreventive bioflavonoid apigenin inhibits prostate cancer cell motility through the focal adhesion kinase/Src signaling mechanism by Franzen, Carrie A, Amargo, Evangeline, Todorović, Viktor, Desai, Bhushan V, Huda, Sabil, Mirzoeva, Salida, Chiu, Karen, Grzybowski, Bartosz A, Chew, Teng-Leong, Green, Kathleen J, Pelling, Jill C

“…Prostate cancer mortality is primarily attributed to metastatic rather than primary, organ-confined disease. Acquiring a motile and invasive phenotype is an…”
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