Search Results - "FRANK, J. L"

Circadian clocks and insulin resistance by Stenvers, Dirk Jan, Scheer, Frank A. J. L., Schrauwen, Patrick, la Fleur, Susanne E., Kalsbeek, Andries

“…Insulin resistance is a main determinant in the development of type 2 diabetes mellitus and a major cause of morbidity and mortality. The circadian timing…”
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Impact of circadian disruption on glucose metabolism: implications for type 2 diabetes by Mason, Ivy C., Qian, Jingyi, Adler, Gail K., Scheer, Frank A. J. L.

“…The circadian system generates endogenous rhythms of approximately 24 h, the synchronisation of which are vital for healthy bodily function. The timing of many…”
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Ghrelin is impacted by the endogenous circadian system and by circadian misalignment in humans by Qian, Jingyi, Morris, Christopher J., Caputo, Rosanna, Garaulet, Marta, Scheer, Frank A. J. L.

“…The human circadian system regulates hunger independently of behavioral factors, resulting in a trough in the biological morning and a peak in the biological…”
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Effects of the Internal Circadian System and Circadian Misalignment on Glucose Tolerance in Chronic Shift Workers by Morris, Christopher J, Purvis, Taylor E, Mistretta, Joseph, Scheer, Frank A. J. L

“…Context: Shift work is a risk factor for diabetes. The separate effects of the endogenous circadian system and circadian misalignment (ie, misalignment between…”
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Pioglitazone and the secondary prevention of cardiovascular disease. A meta-analysis of randomized-controlled trials by de Jong, Marit, van der Worp, H Bart, van der Graaf, Yolanda, Visseren, Frank L J, Westerink, Jan

“…Pioglitazone targets multiple pathogenic pathways involved in the development of cardiovascular diseases (CVD). The aim of this systematic review and…”
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Perivascular adipose tissue as a cause of atherosclerosis by Verhagen, Sandra N, Visseren, Frank L.J

“…Abstract Perivascular adipose tissue surrounds (coronary) arteries and may be involved in local stimulation of atherosclerotic plaque formation. Epicardial…”
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Low-grade inflammation as a risk factor for cardiovascular events and all-cause mortality in patients with type 2 diabetes by Sharif, Shahnam, Van der Graaf, Y, Cramer, M J, Kapelle, L J, de Borst, G J, Visseren, Frank L J, Westerink, Jan

“…Type 2 diabetes is a condition associated with a state of low-grade inflammation caused by adipose tissue dysfunction and insulin resistance. High…”
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Dementia and cognitive decline in type 2 diabetes and prediabetic stages: towards targeted interventions by Biessels, Geert Jan, Prof, Strachan, Mark W J, Prof, Visseren, Frank L J, Prof, Kappelle, L Jaap, Prof, Whitmer, Rachel A, PhD

“…Summary Type 2 diabetes is associated with dementia, and also with more slight cognitive decrements. In this Review we discuss trajectories from normal…”
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Adipose tissue dysfunction in obesity, diabetes, and vascular diseases by Hajer, Gideon R., van Haeften, Timon W., Visseren, Frank L.J.

“…The classical perception of adipose tissue as a storage place of fatty acids has been replaced over the last years by the notion that adipose tissue has a…”
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Obesity and Cancer: The Role of Dysfunctional Adipose Tissue by VAN KRUIJSDIJK, Rob C. M, VAN DER WALL, Elsken, VISSEREN, Frank L. J

“…Overweight and obesity are health problems of epidemic proportions, increasing the risk not only of cardiovascular disease and type 2 diabetes mellitus but…”
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Inclisiran in Patients at High Cardiovascular Risk with Elevated LDL Cholesterol by Ray, Kausik K, Landmesser, Ulf, Leiter, Lawrence A, Kallend, David, Dufour, Robert, Karakas, Mahir, Hall, Tim, Troquay, Roland P.T, Turner, Traci, Visseren, Frank L.J, Wijngaard, Peter, Wright, R. Scott, Kastelein, John J.P

“…Inclisiran, a small interfering RNA that targets PCSK9 mRNA, was given as a single injection at baseline or in two doses at baseline and 90 days. At 180 days,…”
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Association of body mass index and waist circumference with long-term mortality risk in 10,370 coronary patients and potential modification by lifestyle and health determinants by Cruijsen, Esther, Bonekamp, Nadia E, Koopal, Charlotte, Winkels, Renate M, Visseren, Frank L J, Geleijnse, Johanna M

“…Body adiposity is known to affect mortality risk in patients with coronary artery disease (CAD). We examined associations of body mass index (BMI) and waist…”
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Effects of circadian misalignment on cognition in chronic shift workers by Chellappa, Sarah L., Morris, Christopher J., Scheer, Frank A. J. L.

“…Shift work is associated with increased human operational errors, presumably due to the circadian timing system that inhibits optimal cognitive function during…”
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Simvastatin with or without Ezetimibe in Familial Hypercholesterolemia by Kastelein, John J.P, Akdim, Fatima, Stroes, Erik S.G, Zwinderman, Aeilko H, Bots, Michiel L, Stalenhoef, Anton F.H, Visseren, Frank L.J, Sijbrands, Eric J.G, Trip, Mieke D, Stein, Evan A, Gaudet, Daniel, Duivenvoorden, Raphael, Veltri, Enrico P, Marais, A. David, de Groot, Eric

“…In a 2-year clinical trial, the addition of ezetimibe to simvastatin had no effect on the progression of atherosclerosis, as measured by carotid-artery…”
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Daily circadian misalignment impairs human cognitive performance task-dependently by Chellappa, Sarah L., Morris, Christopher J., Scheer, Frank A. J. L.

“…Shift work increases the risk for human errors, such that drowsiness due to shift work has contributed to major industrial disasters, including Space Shuttle…”
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Allopurinol to reduce cardiovascular morbidity and mortality: A systematic review and meta-analysis by van der Pol, Karel H, Wever, Kimberley E, Verbakel, Mariette, Visseren, Frank L J, Cornel, Jan H, Rongen, Gerard A

“…To compare the effectiveness of allopurinol with no treatment or placebo for the prevention of cardiovascular events in hyperuricemic patients. Pubmed, Web of…”
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CIRCUST: A novel methodology for temporal order reconstruction of molecular rhythms; validation and application towards a daily rhythm gene expression atlas in humans by Larriba, Yolanda, Mason, Ivy C, Saxena, Richa, Scheer, Frank A J L, Rueda, Cristina

“…The circadian system drives near-24-h oscillations in behaviors and biological processes. The underlying core molecular clock regulates the expression of other…”
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Modifiable risk factors in adults with and without prior cardiovascular disease: findings from the Indonesian National Basic Health Research by Arsyad, Dian Sidik, Westerink, Jan, Cramer, Maarten J, Ansar, Jumriani, Wahiduddin, Visseren, Frank L J, Doevendans, Pieter A, Ansariadi

“…The majority of risk factors for cardiovascular diseases (CVDs) are modifiable. Continuous monitoring and control of these factors could significantly reduce…”
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Including measures of chronic kidney disease to improve cardiovascular risk prediction by SCORE2 and SCORE2-OP by Matsushita, Kunihiro, Kaptoge, Stephen, Hageman, Steven H J, Sang, Yingying, Ballew, Shoshana H, Grams, Morgan E, Surapaneni, Aditya, Sun, Luanluan, Arnlov, Johan, Bozic, Milica, Brenner, Hermann, Brunskill, Nigel J, Chang, Alex R, Chinnadurai, Rajkumar, Cirillo, Massimo, Correa, Adolfo, Ebert, Natalie, Eckardt, Kai-Uwe, Gansevoort, Ron T, Gutierrez, Orlando, Hadaegh, Farzad, He, Jiang, Hwang, Shih-Jen, Jafar, Tazeen H, Jassal, Simerjot K, Kayama, Takamasa, Kovesdy, Csaba P, Landman, Gijs W, Levey, Andrew S, Lloyd-Jones, Donald M, Major, Rupert W, Miura, Katsuyuki, Muntner, Paul, Nadkarni, Girish N, Nowak, Christoph, Ohkubo, Takayoshi, Pena, Michelle J, Polkinghorne, Kevan R, Sairenchi, Toshimi, Schaeffner, Elke, Schneider, Markus P, Shalev, Varda, Shlipak, Michael G, Solbu, Marit D, Stempniewicz, Nikita, Tollitt, James, Valdivielso, José M, van der Leeuw, Joep, Wang, Angela Yee-Moon, Wen, Chi-Pang, Woodward, Mark, Yamagishi, Kazumasa, Yatsuya, Hiroshi, Zhang, Luxia, Dorresteijn, Jannick A N, Di Angelantonio, Emanuele, Visseren, Frank L J, Pennells, Lisa, Coresh, Josef

“…The 2021 European Society of Cardiology (ESC) guideline on cardiovascular disease (CVD) prevention categorizes moderate and severe chronic kidney disease (CKD)…”
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The readiness of public primary health care (PUSKESMAS) for cardiovascular services in Makasar city, Indonesia by Arsyad, Dian Sidik, Hamsyah, Esliana Fitrida, Qalby, Nurul, Qanitha, Andriany, Westerink, Jan, Cramer, Maarten J, Visseren, Frank L J, Doevendans, Pieter A, Ansariadi, Ansariadi

“…The increasing burden of cardiovascular disease (CVD) has become a major challenge globally, including in Indonesia. Understanding the readiness of primary…”
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