Search Results - "FRANCOTTE, E"

Immobilized halogenophenylcarbamate derivatives of cellulose as novel stationary phases for enantioselective drug analysis by Francotte, E., Huynh, D.

“…Three different halogeno-phenylcarbamate derivatives of cellulose have been prepared and coated on silica gel. The coated materials have been immobilized and…”
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Enantioselective chromatography as a powerful alternative for the preparation of drug enantiomers by Francotte, Eric R

“…The preparative separation of enantiomers by chromatography on chiral stationary phases (CSPs) has been recognized as being a useful alternative to the more…”
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Enantiomer separation by open-tubular liquid chromatography and electrochromatography in cellulose-coated capillaries by FRANCOTTE, E, JUNG, M

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Chiral Inversion and Hydrolysis of Thalidomide:  Mechanisms and Catalysis by Bases and Serum Albumin, and Chiral Stability of Teratogenic Metabolites by Reist, Marianne, Carrupt, Pierre-Alain, Francotte, Eric, Testa, Bernard

“…The chiral inversion and hydrolysis of thalidomide and the catalysis by bases and human serum albumin were investigated by using a stereoselective HPLC assay…”
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In situ characterization of polymorphic forms : The potential of Raman techniques by SZELAGIEWICZ, M, MARCOLLI, C, SCHENKER, R, CIANFERANI, S, HARD, A. P, VIT, A, BURKHARD, A, VON RAUMER, M, HOFMEIER, U. C, ZILIAN, A, FRANCOTTE, E

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Aromatase inhibitors: synthesis, biological activity, and binding mode of azole-type compounds by Furet, P, Batzl, C, Bhatnagar, A, Francotte, E, Rihs, G, Lang, M

“…The enantiomers of the potent nonsteroidal inhibitor of aromatase fadrozole hydrochloride 3 have been separated and their absolute configuration determined by…”
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Applications of simulated moving-bed chromatography to the separation of the enantiomers of chiral drugs by Francotte, Eric R, Richert, Paul

“…Although most preparative chiral separations have been performed in the conventional batch-mode process, interest in simulated moving-bed (SMB) chromatography…”
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Novel Immunomodulator FTY720 Is Phosphorylated in Rats and Humans To Form a Single Stereoisomer. Identification, Chemical Proof, and Biological Characterization of the Biologically Active Species and Its Enantiomer by Albert, Rainer, Hinterding, Klaus, Brinkmann, Volker, Guerini, Danilo, Müller-Hartwieg, Constanze, Knecht, Helmut, Simeon, Corinne, Streiff, Markus, Wagner, Trixie, Welzenbach, Karl, Zécri, Frédéric, Zollinger, Markus, Cooke, Nigel, Francotte, Eric

“…In vivo phosphorylation of FTY720 (1) in rats and humans resulted exclusively in the biologically active (S)-configured enantiomer, which was proven by an ex…”
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Separation of enantiomers by packed capillary electrochromatography on a cellulose-based stationary phase by Mayer, Sabine, Briand, Xavier, Francotte, Eric

“…Separation of enantiomers was performed by applying packed capillary electrochromatography (CEC). Fused-silica capillaries of different lengths with an inner…”
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Isolation and stereospecific determination of the enantiomers of oxindazac by direct liquid chromatographic resolution on triacetylcellulose by Francotte, E, Stierlin, H, Faigle, J W

“…The preparation of the optically pure enantiomers of the antiphlogistic trial drug oxindazac via liquid chromatographic resolution of the corresponding…”
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Immobilized halogenophenylcarbamate derivatives of cellulose as novel stationary phases for enantioselective drug analysis: The impact of enantioseparation techniques on the development and use of chiral drugs by FRANCOTTE, E, HUYNH, D

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Development and validation of chiral high-performance liquid chromatographic methods for the quantitation of valsartan and of the tosylate of valinebenzyl ester by Francotte, Eric, Davatz, Alexander, Richert, Paul

“…A stereospecific HPLC method for the quantitation of CGP 49309 in samples of its corresponding enantiomer valsartan has been developed and validated. The…”
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Simulated moving bed chromatographic resolution of a chiral antitussive by Francotte, Eric, Richert, Paul, Mazzotti, Marco, Morbidelli, Massimo

“…The behavior of a laboratory simulated moving bed (SMB) unit for continuous chromatographic separation of enantiomers has been considered. This was applied to…”
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Novel Amide-Based Molecular Knots: Complete Enantiomeric Separation, Chiroptical Properties, and Absolute Configuration by Vögtle, Fritz, Hünten, Annette, Vogel, Erik, Buschbeck, Sven, Safarowsky, Oliver, Recker, Janosch, Parham, Amir-Hossain, Knott, Michael, Müller, Walter M., Müller, Ute, Okamoto, Yoshio, Kubota, Takateru, Lindner, Wolfgang, Francotte, Eric, Grimme, Stefan

“…By comparison of experimental and theoretical CD curves the absolute configurations of chromatographically baseline‐separated enantiomers of new trefoil…”
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Orally Bioavailable Competitive CCR5 Antagonists by Thoma, Gebhard, Nuninger, François, Schaefer, Marc, Akyel, Kayhan G, Albert, Rainer, Beerli, Christian, Bruns, Christian, Francotte, Eric, Luyten, Marcel, MacKenzie, Duncan, Oberer, Lukas, Streiff, Markus B, Wagner, Trixie, Walter, Hansrudolf, Weckbecker, Gisbert, Zerwes, Hans-Guenter

“…The chemokine receptor CCR5 plays an important role in inflammatory and autoimmune disorders as well as in transplant rejection by affecting the trafficking of…”
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Achiral derivatization as a means of improving the chromatographic resolution of racemic alcohols on benzoylcellulose CSPs by Francotte, Eric

“…The advantages that can be gained from derivatization of various racemic aliphatic and aromatic alcohols prior to enantiomeric chromatographic separation have…”
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Supramolecular effects in the chiral discrimination of meta-methylbenzoyl cellulose in high-performance liquid chromatography by Francotte, Eric, Zhang, Tong

“…A series of chiral stationary phases (CSPs) were prepared from meta-methylbenzoyl cellulose (MMBC) by deposition on silica using different methods (evaporation…”
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Aza analogy to singlet oxygen. The simultaneous stereospecific functionalization of the four cyclopentadiene sp2 carbon atoms by reaction with nitrosochloroethylenes by Viehe, H. G, Merenyi, R, Francotte, E, Van Meerssche, M, Germain, G, Declercq, J. P, Bodart-Gilmont, J

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Comparison of γ-cyclodextrin sulfobutyl ether and unmodified γ-cyclodextrin as chiral selectors in capillary electrophoresis by Jung, Martin, Francotte, Eric

“…γ-Cyclodextrin sulfobutyl ether (γ-CD-SBE) was synthesized and evaluated as a chiral selector for capillary electrophoresis. As expected, the new derivative…”
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Preparative Enzymatic Synthesis of the Acylglucuronide of Mycophenolic Acid by Kittelmann, Matthias, Rheinegger, Urs, Espigat, Aude, Oberer, Lukas, Aichholz, Reiner, Francotte, Eric, Ghisalba, Oreste

“…The acylglucuronide (3) of mycophenolic acid (1) was enzymatically synthesised on a preparative scale (450 mg substrate) under optimised reaction conditions…”
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