Search Results - "FRAN DONG"
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GAD65 Autoantibodies Detected by Electrochemiluminescence Assay Identify High Risk for Type 1 Diabetes
Published in Diabetes (New York, N.Y.) (01-12-2013)“…The identification of diabetes-relevant islet autoantibodies is essential for predicting and preventing type 1 diabetes (T1D). The aim of the current study was…”
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Propensity scores as a novel method to guide sample allocation and minimize batch effects during the design of high throughput experiments
Published in BMC bioinformatics (07-03-2023)“…We developed a novel approach to minimize batch effects when assigning samples to batches. Our algorithm selects a batch allocation, among all possible ways of…”
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Proinsulin/Insulin Autoantibodies Measured With Electrochemiluminescent Assay Are the Earliest Indicator of Prediabetic Islet Autoimmunity
Published in Diabetes care (01-08-2013)“…We evaluated a novel electrochemiluminescent assay for insulin/proinsulin autoantibodies (ECL-IAA) as a new marker of the onset of islet autoimmunity and as a…”
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Increased inflammation is associated with islet autoimmunity and type 1 diabetes in the Diabetes Autoimmunity Study in the Young (DAISY)
Published in PloS one (05-04-2017)“…Type 1 diabetes (TID) is characterized by a loss of pancreatic islet beta cell function resulting in loss of insulin production. Genetic and environmental…”
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Use of a glycomics array to establish the anti-carbohydrate antibody repertoire in type 1 diabetes
Published in Nature communications (01-11-2022)“…Type 1 diabetes (T1D) is an autoimmune disease, characterized by the presence of autoantibodies to protein and non-protein antigens. Here we report the…”
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Investigating iron intake in risk of progression from islet autoimmunity to type 1 diabetes: The diabetes autoimmunity study in the young
Published in Frontiers in immunology (28-03-2023)“…Studies of the role of iron in the risk of type 1 diabetes (T1D) have been inconsistent. Given that iron generates reactive oxygen radicals, which can lead to…”
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An effective processing pipeline for harmonizing DNA methylation data from Illumina's 450K and EPIC platforms for epidemiological studies
Published in BMC research notes (08-09-2021)“…Illumina BeadChip arrays are commonly used to generate DNA methylation data for large epidemiological studies. Updates in technology over time create…”
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Predicting progression to diabetes in islet autoantibody positive children
Published in Journal of autoimmunity (01-06-2018)“…While full oral glucose tolerance test (OGTT) helps improve prediction, it requires intravenous access with 6 sample collections for glucose and C-peptide. The…”
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Epigenome-Wide Association Study of Infant Feeding and DNA Methylation in Infancy and Childhood in a Population at Increased Risk for Type 1 Diabetes
Published in Nutrients (13-11-2021)“…We assessed associations between infant diet (e.g., breastfeeding and introduction to solid foods) and DNA methylation in infancy and childhood. We measured…”
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Unmethylated Insulin as an Adjunctive Marker of Beta Cell Death and Progression to Type 1 Diabetes in Participants at Risk for Diabetes
Published in International journal of molecular sciences (08-08-2019)“…Islet autoantibody (iAb)-positive individuals have a high risk of progression to type 1 diabetes (T1D), although the rate of progression is highly variable and…”
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Decrease in multiple complement proteins associated with development of islet autoimmunity and type 1 diabetes
Published in iScience (16-02-2024)“…Type 1 diabetes (T1D) is a chronic condition caused by autoimmune destruction of the insulin-producing pancreatic β cells. While it is known that…”
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Serum IL-1ra Is Associated with but Has No Genetic Link to Type 1 Diabetes
Published in Endocrines (13-09-2022)“…Interleukin-1 antagonism is a proposed biomarker and potential therapy for the delay and/or treatment of type 1 diabetes (T1D). We evaluated the role of…”
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Higher Sensitivity and Earlier Identification of Celiac Disease Autoimmunity by a Nonradioactive Assay for Transglutaminase Autoantibodies
Published in Journal of immunology research (01-01-2016)“…Higher sensitive transglutaminase autoantibody (TGA) assay will detect the onset of celiac disease (CD) autoimmunity earlier. In developing a nonradioactive…”
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Effect of Low- and High-Calcium Dairy-Based Diets on Macronutrient Oxidation in Humans [Erratum: 2006 May, v. 14, no. 5, p. 928.]
Published in Obesity (Silver Spring, Md.) (01-12-2005)“…OBJECTIVE: Higher calcium and dairy intakes may be associated with lower body weights, but a mechanism in humans has yet to be elucidated. We compared the…”
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The 3p21.31 genetic locus promotes progression to type 1 diabetes through the CCR2/CCL2 pathway
Published in Journal of translational autoimmunity (Online) (01-01-2021)“…Multiple cross-sectional and longitudinal studies have shown that serum levels of the chemokine ligand 2 (CCL-2) are associated with type 1 diabetes (T1D),…”
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Association between change in self-reported sugar intake and a sugar biomarker (δ 13 C) in children at increased risk for type 1 diabetes
Published in Journal of nutritional science (Cambridge) (01-01-2020)“…We examined whether change in added sugar intake is associated with change in δ C, a novel sugar biomarker, in thirty-nine children aged 5-10 years selected…”
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Pediatricians’ Attitudes About Collaborations With Other Community Vaccinators in the Delivery of Seasonal Influenza Vaccine
Published in Academic pediatrics (2012)“…Abstract Objective Achieving universal influenza vaccination among children may necessitate collaborative delivery involving both practices and community…”
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Adherence to Expanded Influenza Immunization Recommendations among Primary Care Providers
Published in The Journal of pediatrics (01-03-2012)“…Objective To assess practices regarding the expanded Advisory Committee on Immunization Practices (ACIP) recommendations for influenza vaccination in children…”
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Prevalence of Parental Concerns About Childhood Vaccines
Published in American journal of preventive medicine (2011)“…Background Little is known about the effects of increased parental vaccine safety concerns on physicians' vaccine communication attitudes and practices…”
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Timing of Adolescent Meningococcal Conjugate Vaccination
Published in American journal of preventive medicine (2011)“…Background The meningococcal conjugate vaccine (MCV4) was recommended for those aged 11–18 years in 2005. Initial supply issues led to an emphasis on…”
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