Search Results - "FRAN DONG"

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  1. 1

    GAD65 Autoantibodies Detected by Electrochemiluminescence Assay Identify High Risk for Type 1 Diabetes by DONGMEI MIAO, GUYER, K. Michelle, FRAN DONG, LING JIANG, STECK, Andrea K, REWERS, Marian, EISENBARTH, George S, LIPING YU

    Published in Diabetes (New York, N.Y.) (01-12-2013)
    “…The identification of diabetes-relevant islet autoantibodies is essential for predicting and preventing type 1 diabetes (T1D). The aim of the current study was…”
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    Propensity scores as a novel method to guide sample allocation and minimize batch effects during the design of high throughput experiments by Carry, Patrick M, Vigers, Tim, Vanderlinden, Lauren A, Keeter, Carson, Dong, Fran, Buckner, Teresa, Litkowski, Elizabeth, Yang, Ivana, Norris, Jill M, Kechris, Katerina

    Published in BMC bioinformatics (07-03-2023)
    “…We developed a novel approach to minimize batch effects when assigning samples to batches. Our algorithm selects a batch allocation, among all possible ways of…”
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  3. 3

    Proinsulin/Insulin Autoantibodies Measured With Electrochemiluminescent Assay Are the Earliest Indicator of Prediabetic Islet Autoimmunity by LIPING YU, FRAN DONG, DONGMEI MIAO, FOUTS, Alexandra R, WENZLAU, Janet M, STECK, Andrea K

    Published in Diabetes care (01-08-2013)
    “…We evaluated a novel electrochemiluminescent assay for insulin/proinsulin autoantibodies (ECL-IAA) as a new marker of the onset of islet autoimmunity and as a…”
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  4. 4

    Increased inflammation is associated with islet autoimmunity and type 1 diabetes in the Diabetes Autoimmunity Study in the Young (DAISY) by Waugh, Kathleen, Snell-Bergeon, Janet, Michels, Aaron, Dong, Fran, Steck, Andrea K, Frohnert, Brigitte I, Norris, Jill M, Rewers, Marian

    Published in PloS one (05-04-2017)
    “…Type 1 diabetes (TID) is characterized by a loss of pancreatic islet beta cell function resulting in loss of insulin production. Genetic and environmental…”
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  5. 5

    Use of a glycomics array to establish the anti-carbohydrate antibody repertoire in type 1 diabetes by Tran, Paul M. H., Dong, Fran, Kim, Eileen, Richardson, Katherine P., Tran, Lynn K. H., Waugh, Kathleen, Hopkins, Diane, Cummings, Richard D., Wang, Peng George, Rewers, Marian J., She, Jin-Xiong, Purohit, Sharad

    Published in Nature communications (01-11-2022)
    “…Type 1 diabetes (T1D) is an autoimmune disease, characterized by the presence of autoantibodies to protein and non-protein antigens. Here we report the…”
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  6. 6

    Investigating iron intake in risk of progression from islet autoimmunity to type 1 diabetes: The diabetes autoimmunity study in the young by Elhassan, Sulafa, Dong, Fran, Buckner, Teresa, Johnson, Randi K, Seifert, Jennifer A, Carry, Patrick M, Vanderlinden, Lauren, Waugh, Kathleen, Rewers, Marian, Norris, Jill M

    Published in Frontiers in immunology (28-03-2023)
    “…Studies of the role of iron in the risk of type 1 diabetes (T1D) have been inconsistent. Given that iron generates reactive oxygen radicals, which can lead to…”
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  7. 7

    An effective processing pipeline for harmonizing DNA methylation data from Illumina's 450K and EPIC platforms for epidemiological studies by Vanderlinden, Lauren A, Johnson, Randi K, Carry, Patrick M, Dong, Fran, DeMeo, Dawn L, Yang, Ivana V, Norris, Jill M, Kechris, Katerina

    Published in BMC research notes (08-09-2021)
    “…Illumina BeadChip arrays are commonly used to generate DNA methylation data for large epidemiological studies. Updates in technology over time create…”
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  8. 8

    Predicting progression to diabetes in islet autoantibody positive children by Steck, Andrea K., Dong, Fran, Frohnert, Brigitte I., Waugh, Kathleen, Hoffman, Michelle, Norris, Jill M., Rewers, Marian J.

    Published in Journal of autoimmunity (01-06-2018)
    “…While full oral glucose tolerance test (OGTT) helps improve prediction, it requires intravenous access with 6 sample collections for glucose and C-peptide. The…”
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  9. 9

    Epigenome-Wide Association Study of Infant Feeding and DNA Methylation in Infancy and Childhood in a Population at Increased Risk for Type 1 Diabetes by Walker-Short, Elizabeth, Buckner, Teresa, Vigers, Timothy, Carry, Patrick, Vanderlinden, Lauren A, Dong, Fran, Johnson, Randi K, Yang, Ivana V, Kechris, Katerina, Rewers, Marian, Norris, Jill M

    Published in Nutrients (13-11-2021)
    “…We assessed associations between infant diet (e.g., breastfeeding and introduction to solid foods) and DNA methylation in infancy and childhood. We measured…”
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  10. 10

    Unmethylated Insulin as an Adjunctive Marker of Beta Cell Death and Progression to Type 1 Diabetes in Participants at Risk for Diabetes by Simmons, Kimber M, Fouts, Alexandra, Pyle, Laura, Clark, Pamela, Dong, Fran, Yu, Liping, Usmani-Brown, Sahar, Gottlieb, Peter, Herold, Kevan C, Steck, Andrea K

    “…Islet autoantibody (iAb)-positive individuals have a high risk of progression to type 1 diabetes (T1D), although the rate of progression is highly variable and…”
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    Serum IL-1ra Is Associated with but Has No Genetic Link to Type 1 Diabetes by Tran, Paul M. H., Dong, Fran, Bin Satter, Khaled, Richardson, Katherine P., Patel, Roshni, Tran, Lynn K. H., Hopkins, Diane, Kolhe, Ravindra, Waugh, Kathleen, Rewers, Marian, Purohit, Sharad

    Published in Endocrines (13-09-2022)
    “…Interleukin-1 antagonism is a proposed biomarker and potential therapy for the delay and/or treatment of type 1 diabetes (T1D). We evaluated the role of…”
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  13. 13

    Higher Sensitivity and Earlier Identification of Celiac Disease Autoimmunity by a Nonradioactive Assay for Transglutaminase Autoantibodies by Yu, Liping, Wang, Yuehui, Liu, Edwin, Dong, Fran, Taki, Iman, Waugh, Kathleen, Miao, Dongmei, Zhao, Zhiyuan, Rewers, Marian

    Published in Journal of immunology research (01-01-2016)
    “…Higher sensitive transglutaminase autoantibody (TGA) assay will detect the onset of celiac disease (CD) autoimmunity earlier. In developing a nonradioactive…”
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  14. 14

    Effect of Low- and High-Calcium Dairy-Based Diets on Macronutrient Oxidation in Humans [Erratum: 2006 May, v. 14, no. 5, p. 928.] by Melanson, Edward L, Donahoo, William T, Dong, Fran, Ida, Therese, Zemel, Michael B

    Published in Obesity (Silver Spring, Md.) (01-12-2005)
    “…OBJECTIVE: Higher calcium and dairy intakes may be associated with lower body weights, but a mechanism in humans has yet to be elucidated. We compared the…”
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    The 3p21.31 genetic locus promotes progression to type 1 diabetes through the CCR2/CCL2 pathway by Tran, Paul MH, Purohit, Sharad, Kim, Eileen, bin Satter, Khaled, Hopkins, Diane, Waugh, Kathleen, Dong, Fran, Onengut-Gumuscu, Suna, Rich, Stephen S., Rewers, Marian, She, Jin-Xiong

    “…Multiple cross-sectional and longitudinal studies have shown that serum levels of the chemokine ligand 2 (CCL-2) are associated with type 1 diabetes (T1D),…”
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    Association between change in self-reported sugar intake and a sugar biomarker (δ 13 C) in children at increased risk for type 1 diabetes by Henze, Martha M, Bemis, Elizabeth A, Seifert, Jennifer A, Johnson, Randi K, Dong, Fran, Rewers, Marian, Norris, Jill M

    Published in Journal of nutritional science (Cambridge) (01-01-2020)
    “…We examined whether change in added sugar intake is associated with change in δ C, a novel sugar biomarker, in thirty-nine children aged 5-10 years selected…”
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