Search Results - "FRACASSO, R. P"

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    Deposits of Amyloid β Protein in the Central Nervous System of Transgenic Mice by Wirak, D. O., Bayney, R., Ramabhadran, T. V., Fracasso, R. P., Hart, J. T., Hauer, P. E., Hsiau, P., Pekar, S. K., Scangos, G. A., Trapp, B. D., Unterbeck, A. J.

    “…Alzheimer's disease is characterized by widespread deposition of amyloid in the central nervous system. The 4-kilodalton amyloid β protein is derived from a…”
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    Use of recombinant fusion proteins for generation and rapid characterization of monoclonal antibodies. Application to the Kunitz domain of human beta amyloid precursor protein by Wunderlich, D, Lee, A, Fracasso, R P, Mierz, D V, Bayney, R M, Ramabhadran, T V

    Published in Journal of immunological methods (14-02-1992)
    “…Production of peptides by recombinant DNA techniques is an efficient alternative to chemical synthesis of peptides. Proteins and peptides produced by…”
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    Phosphorylation-dependent Monoclonal Tau Antibodies Do Not Reliably Report Phosphorylation by Extracellular Signal-regulated Kinase 2 at Specific Sites by Roder, Hanno M., Fracasso, R. Paul, Hoffman, Frederick J., Witowsky, James A., Davis, Gary, Pellegrino, Carla B.

    Published in The Journal of biological chemistry (14-02-1997)
    “…Analysis of phosphorylation of tau, the microtubule-associated proteins hyperphosphorylated in Alzheimer's disease, is often performed using…”
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    Inhibition of PHF-like tau hyperphosphorylation in SH-SY5Y cells and rat brain slices by K252a by Hübinger, Gabriele, Geis, Silvia, LeCorre, Sylvie, Mühlbacher, Susanne, Gordon, Sandra, Fracasso, R Paul, Hoffman, Fred, Ferrand, Sandrine, Klafki, Hans W, Roder, Hanno M

    Published in Journal of Alzheimer's disease (01-04-2008)
    “…Abnormal hyperphosphorylation of tau is believed to constitute a critical biochemical event in the process of neurofibrillary degeneration of Alzheimer's…”
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