Search Results - "FRÖLICH, J. C"

A classification of NSAIDs according to the relative inhibition of cyclooxygenase isoenzymes by Froelich, J C

“…Non-steroidal anti-inflammatory drugs (NSAIDs) are, as a group, the most frequently consumed drugs worldwide. They also cause the most, and often dangerous,…”
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Nebivolol decreases systemic oxidative stress in healthy volunteers by Troost, R., Schwedhelm, E., Rojczyk, S., Tsikas, D., Frölich, J. C.

“…Aims Nebivolol is a selective, vasodilatory β1‐adrenergic receptor antagonist which has been suggested to possess additional antioxidative properties. The aim…”
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Asymmetric dimethylarginine plasma concentrations differ in patients with end-stage renal disease : Relationship to treatment method and atherosclerotic disease by KIELSTEIN, J. T, BÖGER, R. H, BODE-BÖGER, S. M, SCHÄFFER, J, BARBEY, M, KOCH, K. M, FRÖLICH, J. C

“…Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of endothelial nitric oxide (NO) synthase. Its concentration is elevated in patients with…”
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Biochemical evidence for impaired nitric oxide synthesis in patients with peripheral arterial occlusive disease by BÖGER, R. H, BODE-BÖGER, S. M, THIELE, W, JUNKER, W, ALEXANDER, K, FRÖLICH, J. C

“…We studied urinary nitrate and cGMP excretion rates, indices of systemic NO formation, and plasma concentrations of L-arginine and the endogenous NO synthase…”
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COX-2 and the kidneys by Stichtenoth, D O, Frölich, J C

“…The kidney is the second most frequent target of serious adverse effects of non-steroidal antiinflammatory drugs (NSAIDs). The renal side effects of NSAIDs…”
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Low dialysance of asymmetric dimethylarginine (ADMA)--in vivo and in vitro evidence of significant protein binding by Kielstein, J T, Böger, R H, Bode-Böger, S M, Martens-Lobenhoffer, J, Lonnemann, G, Frölich, J C, Haller, H, Fliser, D

“…Increased blood levels of the endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine (ADMA) predict cardiovascular mortality in patients with…”
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L-arginine infusion decreases peripheral arterial resistance and inhibits platelet aggregation in healthy subjects by Bode-Böger, S M, Böger, R H, Creutzig, A, Tsikas, D, Gutzki, F M, Alexander, K, Frölich, J C

“…1. L-Arginine is the physiological precursor of nitric oxide which induces vasodilatation and inhibits platelet aggregation by the formation of cyclic GMP. 2…”
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L‐arginine‐induced vasodilation in healthy humans:pharmacokinetic–pharmacodynamic relationship by Bode‐Böger, Stefanie M., Böger, Rainer H., Galland, Andrea, Tsikas, Dimitrios, Frölich, Jürgen C.

“…Aims Administration of l‐arginine by intravenous infusion or via oral absorption has been shown to induce peripheral vasodilation in humans, and to improve…”
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Dietary L-arginine reduces the progression of atherosclerosis in cholesterol-fed rabbits: Comparison with lovastatin by BÖGER, R. H, BODE-BÖGER, S. M, BRANDES, R. P, PHIVTHONG-NGAM, L, BÖHME, M, NAFE, R, MÜGGE, A, FRÖLICH, J. C

“…We investigated whether L-arginine induces regression of preexisting atheromatous lesions and reversal of endothelial dysfunction in hypercholesterolemic…”
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Selective Attenuation of Endothelium-Mediated Vasodilation in Atherosclerotic Human Coronary Arteries by Förstermann, Ulrich, Mügge, Andreas, Alheid, Ute, Haverich, Axel, Frölich, Jürgen C

“…This study was undertaken to determine whether atherosclerosis impairs relaxations mediated by endothelium-derived relaxing factor (EDRF) in human coronary…”
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Cigarette smoking stimulates cysteinyl leukotriene production in man by Fauler, J., Frölich, J. C.

“…Chronic cigarette smoking is an important risk factor for pulmonary and cardiovascular diseases. An increased production of cysteinyl leukotrienes has been…”
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The l-arginine—nitric oxide pathway: role in atherosclerosis and therapeutic implications by Böger, Rainer H., Bode-Böger, Stefanie M., Frölich, Jürgen C.

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L-arginine induces nitric oxide-dependent vasodilation in patients with critical limb ischemia : a randomized, controlled study by BODE-BÖGER, S. M, BÖGER, R. H, ALFKE, H, HEINZEL, D, TSIKAS, D, CREUTZIG, A, ALEXANDER, K, FRÖLICH, J. C

“…L-Arginine is the precursor of endogenous nitric oxide (NO), which is a potent vasodilator acting via the intracellular second-messenger cGMP. In healthy…”
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Urinary nitrate excretion is increased in patients with rheumatoid arthritis and reduced by prednisolone by Stichtenoth, D O, Fauler, J, Zeidler, H, Frölich, J C

“…OBJECTIVES--To determine daily production of nitric oxide (NO) measured as urinary nitrate excretion, and the effect of prednisolone in patients with…”
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Recombinant human erythropoietin enhances vasoconstrictor tone via endothelin-1 and constrictor prostanoids by Bode-Böger, Stefanie M., Böger, Rainer H., Kuhn, Michaela, Radermacher, Jörg, Frölich, Jürgen C.

“…Recombinant human erythropoietin enhances vasoconstrictor tone via endothelin-1 and constrictor prostanoids. Hypertension is the main side effect developing in…”
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Elevated nitric oxide levels in patients with chronic liver disease and cirrhosis correlate with disease stage and parameters of hyperdynamic circulation by Arkenau, H T, Stichtenoth, D O, Frölich, J C, Manns, M P, Böker, K H W

“…Chronic liver diseases are accompanied by changes in splanchnic and systemic circulation. These changes are characterised by a reduction in peripheral vascular…”
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Dietary l-arginine and α-tocopherol reduce vascular oxidative stress and preserve endothelial function in hypercholesterolemic rabbits via different mechanisms by Böger, Rainer H., Bode-Böger, Stefanie M., Phivthong-ngam, Laddaval, Brandes, Ralf P., Schwedhelm, Edzard, Mügge, Andreas, Böhme, Michael, Tsikas, Dimitrios, Frölich, Jürgen C.

“…Vascular oxidative stress brought about by superoxide radicals and oxidized low-density lipoproteins (oxLDL) is a major factor contributing to decreased…”
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Dietary l-arginine decreases myointimal cell proliferation and vascular monocyte accumulation in cholesterol-fed rabbits by Böger, Rainer H, Bode-Böger, Stefanie M, Kienke, Sven, Stan, Alexandru C, Nafe, Reinhold, Frölich, Jürgen C

“…l-arginine, the precursor of endogenous nitric oxide (NO), has been shown to enhance endothelial function and to reduce the progression of atherosclerosis in…”
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Effects of very low dose and enteric-coated acetylsalicylic acid on prostacyclin and thromboxane formation and on bleeding time in healthy subjects by BODE-BÖGER, S. M, BÖGER, R. H, SCHUBERT, M, FRÖLICH, J. C

“…Low dose acetylsalicylic acid (ASA) is widely used as an anti-aggregatory agent in the primary and secondary prevention of cardiovascular diseases. In an…”
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Importance of NO/EDRF for glomerular and tubular function: Studies in the isolated perfused rat kidney by Radermacher, Jörg, Klanke, Bernd, Schurek, Hans-Joachim, Stolte, Hilmar F., Frölich, Jürgen C.

“…Importance of NO/EDRF for glomerular and tubular function: Studies in the isolated perfused rat kidney. The effect of the addition of Nω-nitro-L-arginine…”
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