Search Results - "FRÖHLICH, Eleonore"

Oral inhalation for delivery of proteins and peptides to the lungs by Fröhlich, Eleonore, Salar-Behzadi, Sharareh

“…[Display omitted] •Main use in obstructive lung diseases and acute respiratory distress syndrome.•Aerosolisation of liquid formulations is the most common…”
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Thyroid Autoimmunity: Role of Anti-thyroid Antibodies in Thyroid and Extra-Thyroidal Diseases by Fröhlich, Eleonore, Wahl, Richard

“…Autoimmune diseases have a high prevalence in the population, and autoimmune thyroid disease (AITD) is one of the most common representatives. Thyroid…”
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Cellular targets and mechanisms in the cytotoxic action of non-biodegradable engineered nanoparticles by Fröhlich, Eleonore

“…The use of nanoparticles (NPs) has improved the quality of many industrial, pharmaceutical, and medical products. Increased surface reactivity, a major reason…”
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Role of omics techniques in the toxicity testing of nanoparticles by Fröhlich, Eleonore

“…Nanotechnology is regarded as a key technology of the twenty-first century. Despite the many advantages of nanotechnology it is also known that engineered…”
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Action of Nanoparticles on Platelet Activation and Plasmatic Coagulation by Fröhlich, Eleonore

“…Nanomaterials can get into the blood circulation after injection or by release from implants but also by permeation of the epithelium after oral, respiratory…”
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The Variety of 3D Breast Cancer Models for the Study of Tumor Physiology and Drug Screening by Fröhlich, Eleonore

“…Breast cancer is the most common cancer in women and responsible for multiple deaths worldwide. 3D cancer models enable a better representation of tumor…”
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Therapeutic Potential of Mesenchymal Stem Cells and Their Products in Lung Diseases-Intravenous Administration versus Inhalation by Fröhlich, Eleonore

“…The number of publications studying the therapeutic use of stem cells has steadily increased since 2000. Compared to other applications, there has been little…”
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Animals in Respiratory Research by Fröhlich, Eleonore

“…The respiratory barrier, a thin epithelial barrier that separates the interior of the human body from the environment, is easily damaged by toxicants, and…”
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The role of surface charge in cellular uptake and cytotoxicity of medical nanoparticles by Fröhlich, Eleonore

“…Many types of nanoparticles (NPs) are tested for use in medical products, particularly in imaging and gene and drug delivery. For these applications, cellular…”
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The forgotten effects of thyrotropin-releasing hormone: Metabolic functions and medical applications by Fröhlich, Eleonore, Wahl, Richard

“…[Display omitted] •Hypothalamic releasing hormone has endocrine targets and affects cognitive functions.•TRH stimulation assay is no more widely used in the…”
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Replacement Strategies for Animal Studies in Inhalation Testing by Fröhlich, Eleonore

“…Animal testing is mandatory in drug testing and is the gold standard for toxicity and efficacy evaluations. This situation is expected to change in the future…”
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Cytotoxicity of Nanoparticles Contained in Food on Intestinal Cells and the Gut Microbiota by Frohlich, Esther E, Frohlich, Eleonore

“…Toxicity of nanoparticles (NPs) upon oral exposure has been studied in animals using physiological changes, behavior, histology, and blood analysis for…”
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Cognitive Impairment by Antibiotic-Induced Gut Dysbiosis: Analysis of Gut Microbiota-Brain Communication by Fröhlich, Esther E, Farzi, Aitak, Mayerhofer, Raphaela, Reichmann, Florian, Jačan, Angela, Wagner, Bernhard, Zinser, Erwin, Bordag, Natalie, Magnes, Christoph, Fröhlich, Eleonore, Kashofer, Karl, Gorkiewicz, Gregor, Holzer, Peter

“…Highlights • Antibiotic treatment of adult mice impairs object recognition but not spatial memory. • Gut microbiota disruption alters the metabolic profiles in…”
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Cellular elimination of nanoparticles by Frohlich, Eleonore

“…Highlights • Particle dissolution contributes to cellular elimination. • Lysosomal exocytosis is the main mechanism for nanoparticle excretion. • Cells with…”
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Chemotherapy and Chemoprevention by Thiazolidinediones by Fröhlich, Eleonore, Wahl, Richard

“…Thiazolidinediones (TZDs) are synthetic ligands of Peroxisome-Proliferator-Activated Receptor gamma (PPARγ). Troglitazone, rosiglitazone, and pioglitazone have…”
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Oral uptake of nanoparticles: human relevance and the role of in vitro systems by Fröhlich, Eleonore, Roblegg, Eva

“…Nanoparticles (NPs) present in environment, consumer and health products, food and medical applications lead to a high degree of human exposure and concerns…”
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Toxicological assessment of inhaled nanoparticles: role of in vivo, ex vivo, in vitro, and in silico studies by Fröhlich, Eleonore, Salar-Behzadi, Sharareh

“…The alveolar epithelium of the lung is by far the most permeable epithelial barrier of the human body. The risk for adverse effects by inhaled nanoparticles…”
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Pars Distalis and Pars Tuberalis Thyroid-Stimulating Hormones and Their Roles in Macro-Thyroid-Stimulating Hormone Formation by Fröhlich, Eleonore, Wahl, Richard

“…Thyroid-stimulating hormone (TSH) and thyroid hormone levels are standard parameters in blood analysis. However, the immunoassays employed may lead to…”
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Models for oral uptake of nanoparticles in consumer products by Fröhlich, Eleonore, Roblegg, Eva

“…Abstract Presently, many consumer products contain nano-sized materials (NMs) to improve material properties, product quality and ease of use. NMs in food…”
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Value of phagocyte function screening for immunotoxicity of nanoparticles in vivo by Frohlich, Eleonore

“…Nanoparticles (NPs) present in the environment and in consumer products can cause immunotoxic effects. The immune system is very complex, and in vivo studies…”
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