Search Results - "FOWLER, Joseph"
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T-cell inhibitors for atopic dermatitis
Published in Journal of the American Academy of Dermatology (01-03-2018)“…The management of atopic dermatitis is changing with the development of novel biologic agents to target specific molecules in the inflammatory cascade…”
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North American Contact Dermatitis Group Patch Test Results: 2019-2020
Published in Dermatitis (01-03-2023)“…Patch testing is an important diagnostic tool for assessment of allergic contact dermatitis (ACD). This study documents the North American Contact Dermatitis…”
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Cobalt
Published in Dermatitis (01-01-2016)“…Cobalt has been a recognized allergen capable of causing contact dermatitis for decades. Why, therefore, has it been named 2016 "Allergen of the Year"? Simply…”
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North American Contact Dermatitis Group Patch Test Results: 2015-2016
Published in Dermatitis (01-11-2018)“…Patch testing is an important diagnostic tool for the assessment of allergic contact dermatitis (ACD). This study documents the North American Contact…”
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5
Dynamic metabolism of endothelial triglycerides protects against atherosclerosis in mice
Published in The Journal of clinical investigation (15-02-2024)“…Blood vessels are continually exposed to circulating lipids, and elevation of ApoB-containing lipoproteins causes atherosclerosis. Lipoprotein metabolism is…”
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Trends in the Prevalence of Methylchloroisothiazolinone/Methylisothiazolinone Contact Allergy in North America and Europe
Published in JAMA dermatology (Chicago, Ill.) (01-03-2023)“…The common use of isothiazolinones as preservatives is a global cause of allergic contact dermatitis. Differences in allowable concentrations of…”
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Occupational contact dermatitis: Retrospective analysis of North American Contact Dermatitis Group Data, 2001 to 2016
Published in Journal of the American Academy of Dermatology (01-04-2022)“…Patch testing is an important diagnostic tool for suspected allergic contact dermatitis (ACD) in occupational settings. Provide an overview of occupational…”
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North American Contact Dermatitis Group Patch Test Results 2013-2014
Published in Dermatitis (01-01-2017)“…Patch testing is the most important diagnostic tool for the assessment of allergic contact dermatitis. This study documents the North American Contact…”
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North American contact dermatitis group patch test results: 2011-2012
Published in Dermatitis (01-01-2015)“…Patch testing is an important diagnostic tool for assessment of allergic contact dermatitis (ACD). This study documents the North American Contact Dermatitis…”
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Inflammatory stress signaling via NF-kB alters accessible cholesterol to upregulate SREBP2 transcriptional activity in endothelial cells
Published in eLife (12-08-2022)“…There is a growing appreciation that a tight relationship exists between cholesterol homeostasis and immunity in leukocytes; however, this relationship has not…”
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Macrophage-Derived 25-Hydroxycholesterol Promotes Vascular Inflammation, Atherogenesis, and Lesion Remodeling
Published in Circulation (New York, N.Y.) (31-01-2023)“…Cross-talk between sterol metabolism and inflammatory pathways has been demonstrated to significantly affect the development of atherosclerosis. Cholesterol…”
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BMP-9 and LDL crosstalk regulates ALK-1 endocytosis and LDL transcytosis in endothelial cells
Published in The Journal of biological chemistry (25-12-2020)“…Bone morphogenetic protein-9 (BMP-9) is a circulating cytokine that is known to play an essential role in the endothelial homeostasis and the binding of BMP-9…”
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Genome-wide RNAi screen reveals ALK1 mediates LDL uptake and transcytosis in endothelial cells
Published in Nature communications (21-11-2016)“…In humans and animals lacking functional LDL receptor (LDLR), LDL from plasma still readily traverses the endothelium. To identify the pathways of LDL uptake,…”
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Contact dermatitis associated with preservatives: Retrospective analysis of North American Contact Dermatitis Group data, 1994 through 2016
Published in Journal of the American Academy of Dermatology (01-04-2021)“…Preservatives are often necessary components of commercial products. Large-scale North American studies on preservative allergy are limited. To evaluate…”
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SREBP2 regulates the endothelial response to cytokines via direct transcriptional activation of KLF6
Published in Journal of lipid research (01-08-2023)“…Cholesterol homeostasis plays a significant role in disease pathogenesis in chronic disorders such as cardiovascular and kidney diseases. The transcription…”
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Prevalence and trend of allergen sensitization in patients with cheilitis referred for patch testing, North American Contact Dermatitis Group data, 2001–2018
Published in Contact dermatitis (01-04-2023)“…Background An updated understanding of allergic contact cheilitis is needed. Objectives To characterize clinical characteristics and allergen relevance in…”
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Contact dermatitis to personal care products is increasing (but different!) in males and females: North American Contact Dermatitis Group data, 1996-2016
Published in Journal of the American Academy of Dermatology (01-12-2021)“…Personal care products (PCPs) are commonly responsible for allergic contact dermatitis and irritant contact dermatitis. PCP use was historically associated…”
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Innovations in natural ingredients and their use in skin care
Published in Journal of drugs in dermatology (01-06-2010)“…Natural ingredients have been used traditionally for millennia and their application in topical creams, lotions and preparations within the traditional…”
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Age-related differences in patch testing results among children: Analysis of North American Contact Dermatitis Group Data, 2001-2018
Published in Journal of the American Academy of Dermatology (01-04-2022)“…An updated understanding of allergic contact dermatitis is needed, particularly in children. To compare positive and clinically relevant reactions in children…”
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Effects of Merino Wool on Atopic Dermatitis Using Clinical, Quality of Life, and Physiological Outcome Measures
Published in Dermatitis (01-05-2019)“…Wool clothing may be perceived as a poor choice for use by individuals with sensitive skin or atopic dermatitis. The aims of the study were to evaluate the…”
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