Search Results - "FOUREZ, Lindsey M"
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Identification of a naturally-occurring canine model for early detection and intervention research in high grade urothelial carcinoma
Published in Frontiers in oncology (11-11-2022)“…Early detection and intervention research is expected to improve the outcomes for patients with high grade muscle invasive urothelial carcinoma (InvUC). With…”
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Targeting Folate Receptors to Treat Invasive Urinary Bladder Cancer
Published in Cancer research (Chicago, Ill.) (15-01-2013)“…Folate receptors (FR) may be of use for targeted delivery of cytotoxic drugs in invasive urothelial carcinoma (iUC), for which improved therapy is needed. FR…”
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Phase I/II Trial of Vemurafenib in Dogs with Naturally Occurring, BRAF -mutated Urothelial Carcinoma
Published in Molecular cancer therapeutics (01-11-2021)“…BRAF-targeted therapies including vemurafenib (Zelboraf) induce dramatic cancer remission; however, drug resistance commonly emerges. The purpose was to…”
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Ultrasonographic detection of apex nodules in the urinary bladder of Scottish Terriers
Published in Veterinary radiology & ultrasound (01-03-2022)“…An apex nodule was recently identified in the urinary bladder of Scottish Terriers being screened for bladder cancer at our institution. This prospective,…”
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Marked paraneoplastic basophilia in a cat with alimentary T‐cell lymphoma
Published in Veterinary clinical pathology (01-03-2024)“…An 8‐year‐old, spayed female domestic shorthair cat was presented for acute weight loss, hyporexia, intermittent vomiting, and loose stools. A caudal abdominal…”
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Phase I/II clinical trial of the targeted chemotherapeutic drug, folate-tubulysin, in dogs with naturally-occurring invasive urothelial carcinoma
Published in Oncotarget (11-12-2018)“…The purpose was to determine the safety and antitumor activity of a folate-tubulysin conjugate (EC0531) in a relevant preclinical animal model, dogs with…”
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Basal and Luminal Molecular Subtypes in Naturally-Occurring Canine Urothelial Carcinoma are Associated with Tumor Immune Signatures and Dog Breed
Published in Bladder cancer (01-01-2021)“…BACKGROUND: Improved therapies are needed for patients with invasive urothelial carcinoma (InvUC). Tailoring treatment to molecular subtypes holds promise, but…”
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Effects of cyclooxygenase inhibitor treatment on the renal toxicity of cisplatin in rats
Published in Cancer chemotherapy and pharmacology (01-02-2010)“…Purpose The purpose of this study was to determine the effects of a nonselective cyclooxygenase (cox) inhibitor and of a selective cox-2 inhibitor on the renal…”
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Marked paraneoplastic basophilia in a cat with alimentary T-cell lymphoma
Published in Veterinary clinical pathology (01-03-2024)“…An 8-year-old, spayed female domestic shorthair cat was presented for acute weight loss, hyporexia, intermittent vomiting, and loose stools. A caudal abdominal…”
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