Search Results - "FOULKES, S."
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Detection of Atrial Fibrillation in a Large Population Using Wearable Devices: The Fitbit Heart Study
Published in Circulation (New York, N.Y.) (08-11-2022)“…Morbidity from undiagnosed atrial fibrillation (AF) may be preventable with early detection. Many consumer wearables contain optical photoplethysmography (PPG)…”
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ECG-Based Deep Learning and Clinical Risk Factors to Predict Atrial Fibrillation
Published in Circulation (New York, N.Y.) (11-01-2022)“…Artificial intelligence (AI)-enabled analysis of 12-lead ECGs may facilitate efficient estimation of incident atrial fibrillation (AF) risk. However, it…”
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3
It’s time to swim! Zebrafish and the circadian clock
Published in FEBS letters (20-05-2011)“…The zebrafish represents a fascinating model for studying key aspects of the vertebrate circadian timing system. Easy access to early embryonic development has…”
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Rationale and design of a large population study to validate software for the assessment of atrial fibrillation from data acquired by a consumer tracker or smartwatch: The Fitbit heart study
Published in The American heart journal (01-08-2021)“…[Display omitted] Early detection of atrial fibrillation or flutter (AF) may enable prevention of downstream morbidity. Consumer wrist-worn wearable technology…”
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5
Early-life lead exposure induces long-term toxicity in the central nervous system: From zebrafish larvae to juveniles and adults
Published in The Science of the total environment (15-01-2022)“…Lead induced neurotoxicity has been extensively investigated. However, the potential connections between early-life lead exposure and the frequently observed…”
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Comparison of anxiety-like and social behaviour in medaka and zebrafish
Published in Scientific reports (28-06-2022)“…The medaka, Oryzias latipes , is rapidly growing in importance as a model in behavioural research. However, our knowledge of its behaviour is still incomplete…”
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Evolution Shapes the Gene Expression Response to Oxidative Stress
Published in International journal of molecular sciences (21-06-2019)“…Reactive oxygen species (ROS) play a key role in cell physiology and function. ROS represents a potential source of damage for many macromolecules including…”
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8
Negative phototaxis in the photosymbiotic sea anemone Aiptasia as a potential strategy to protect symbionts from photodamage
Published in Scientific reports (19-10-2023)“…Photosymbiotic cnidarians generally seek bright environments so that their symbionts can be photosynthetically active. However, excess light may result in a…”
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Reactive Oxygen Species Signaling and Oxidative Stress: Transcriptional Regulation and Evolution
Published in Antioxidants (01-03-2024)“…Since the evolution of the aerobic metabolism, reactive oxygen species (ROS) have represented significant challenges to diverse life forms. In recent decades,…”
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10
A guide to genome-wide association analysis and post-analytic interrogation
Published in Statistics in medicine (10-12-2015)“…This tutorial is a learning resource that outlines the basic process and provides specific software tools for implementing a complete genome‐wide association…”
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Photoreceptor Diversification Accompanies the Evolution of Anthozoa
Published in Molecular biology and evolution (04-05-2021)“…Abstract Anthozoan corals are an ecologically important group of cnidarians, which power the productivity of reef ecosystems. They are sessile, inhabit…”
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Functional principal component analysis and sparse-group LASSO to identify associations between biomarker trajectories and mortality among hospitalized SARS-CoV-2 infected individuals
Published in BMC medical research methodology (28-10-2023)“…Abstract Background A substantial body of clinical research involving individuals infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)…”
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13
Genetically Blocking the Zebrafish Pineal Clock Affects Circadian Behavior
Published in PLoS genetics (21-11-2016)“…The master circadian clock in fish has been considered to reside in the pineal gland. This dogma is challenged, however, by the finding that most zebrafish…”
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Sex differences in inflammatory markers in patients hospitalized with COVID-19 infection: Insights from the MGH COVID-19 patient registry
Published in PloS one (28-04-2021)“…Men are at higher risk for serious complications related to COVID-19 infection than women. More robust immune activation in women has been proposed to…”
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A blind circadian clock in cavefish reveals that opsins mediate peripheral clock photoreception
Published in PLoS biology (01-09-2011)“…The circadian clock is synchronized with the day-night cycle primarily by light. Fish represent fascinating models for deciphering the light input pathway to…”
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Pegylated Interferon Alfa-2a Monotherapy Results in Suppression of HIV Type 1 Replication and Decreased Cell-Associated HIV DNA Integration
Published in The Journal of infectious diseases (15-01-2013)“…Background. Antiretroviral therapy (ART)-mediated immune reconstitution fails to restore the capacity of the immune system to spontaneously control human…”
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Light directs zebrafish period2 expression via conserved D and E boxes
Published in PLoS biology (27-10-2009)“…For most species, light represents the principal environmental signal for entraining the endogenous circadian clock. The zebrafish is a fascinating vertebrate…”
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Finding Nemo’s clock reveals switch from nocturnal to diurnal activity
Published in Scientific reports (24-03-2021)“…Timing mechanisms play a key role in the biology of coral reef fish. Typically, fish larvae leave their reef after hatching, stay for a period in the open…”
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The light responsive transcriptome of the zebrafish: function and regulation
Published in PloS one (15-02-2011)“…Most organisms possess circadian clocks that are able to anticipate the day/night cycle and are reset or "entrained" by the ambient light. In the zebrafish,…”
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Prospective use of whole genome sequencing (WGS) detected a multi-country outbreak of Salmonella Enteritidis
Published in Epidemiology and infection (01-01-2017)“…Since April 2015, whole genome sequencing (WGS) has been the routine test for Salmonella identification, surveillance and outbreak investigation at the…”
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