Search Results - "FOULKES, J. GORDON"

A genome‐wide strategy for the identification of essential genes in Staphylococcus aureus by Forsyth, R. Allyn, Haselbeck, Robert J., Ohlsen, Kari L., Yamamoto, Robert T., Xu, Howard, Trawick, John D., Wall, Daniel, Wang, Liangsu, Brown‐Driver, Vickie, Froelich, Jamie M., C., Kedar G., King, Paula, McCarthy, Melissa, Malone, Cheryl, Misiner, Brian, Robbins, David, Tan, Zehui, Zhu, Zhan‐yang, Carr, Grant, Mosca, Deborah A., Zamudio, Carlos, Foulkes, J. Gordon, Zyskind, Judith W.

“…Summary To address the need for new approaches to antibiotic drug development, we have identified a large number of essential genes for the bacterial pathogen,…”
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Transcription-modulating drugs: mechanism and selectivity by Cai, Weizhong, Hu, Lan, Foulkes, J Gordon

“…Transcription-modulating drugs achieve their therapeutic effects through the modulation of gene transcription. To understand how selectivity is achieved, four…”
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Abelson-transformed fibroblasts contain nuclear phosphotyrosyl-proteins which preferentially bind to murine DNA by Bell, John C, Mahadevan, Louis C, Colledge, William H, Frackelton, A. Raymond, Sargent, Michael G, Foulkes, J. Gordon

“…Protein-tyrosine kinases, either in the form of growth-factor receptors or as the polypeptide products of oncogenes, appear to be important in the regulation…”
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The regulation of glycogen metabolism. Purification and properties of protein phosphatase inhibitor-2 from rabbit skeletal muscle by Foulkes, J G, Cohen, P

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Effects of Skeletal Muscle Protein Phosphatase Inhibitor-2 on Protein Synthesis and Protein Phosphorylation in Rabbit Reticulocyte Lysates by Ernst, Vivian, Levin, Daniel H., Foulkes, J. Gordon, London, Irving M.

“…Reticulocyte lysates contain two major classes of protein phosphatase activities, designated type 1 and type 2. These designations are based on criteria…”
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The Hormonal Control of Glycogen Metabolism by FOULKES, J. Gordon, COHEN, Philip

“…Inhibitor‐1 has been shown to be phosphorylated in skeletal muscle in vivo. In normal fed animals the degree of phosphorylation was 31 ± 7% and this value…”
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A Kinetic Analysis of the Effects of Inhibitor‐1 and Inhibitor‐2 on the Activity of Protein Phosphatase‐1 by FOULKES, J. Gordon, STRADA, Samuel J., HENDERSON, Peter J. F., COHEN, Philip

“…The steady‐state interaction between protein phosphatase‐1 and its two inhibitor proteins was studied in vitro at low enzyme concentrations where the…”
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Identification of Another Member of the Transforming Growth Factor Type β Gene Family by Dijke, Peter Ten, Hansen, Pamela, Iwata, Kenneth K., Pieler, Christian, Foulkes, J. Gordon

“…We report here the complete amino acid sequence of another member of the type β transforming growth factor gene family, deduced from the nucleotide sequence of…”
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Protein phosphatase inhibitor-1 and inhibitor-2 from rabbit skeletal muscle by Cohen, P, Foulkes, J G, Holmes, C F, Nimmo, G A, Tonks, N K

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Sequences of the A-MuLV protein needed for fibroblast and lymphoid cell transformation by Prywes, R, Foulkes, J G, Rosenberg, N, Baltimore, D

“…The role of various segments (gag or v-abl) of the Abelson murine leukemia virus (A-MuLV) genome in both lymphoid cell and fibroblast transformation was…”
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The Proteink Phosphatases Involved in Cellur Regulation. 2. Glycogen Metabolism by INGERBRITSEN, Thomas S., FOULKES, J. Gordon, COHEN, Philip

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Cell Lines and Peripheral Blood Leukocytes Derived from Individuals with Chronic Myelogenous Leukemia Display Virtually Identical Proteins Phosphorylated on Tyrosine Residues by Huhn, Richard D., Posner, Marshall R., Rayter, Sydonia I., Foulkes, J. Gordon, Frackelton, A. Raymond

“…An aberrant p210BCR-ABL protein that possesses constitutive protein-tyrosine kinase activity is presumed to be involved in the development of the neoplastic…”
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Detection of a novel mammalian protein phosphatase with activity for phosphotyrosine by Foulkes, J.Gordon, Howard, Randall F., Ziemiecki, Andrew

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Gene Expression as a Target for New Drug Discovery by HEGUY, ADRIANA, STEWART, ALEXANDER A., HALEY, JOHN D., SMITH, DAVID E., FOULKES, J. GORDON

“…Over the last 7 years we have carried out a major research effort focused on gene transcription as a novel approach to drug discovery. The goal is to identify…”
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Phosphotyrosyl-protein phosphatases by Foulkes, J G

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Phosphorylation of Ribosomal Protein S6 on Serine after Microinjection of the Abelson Murine Leukemia Virus Tyrosine-Specific Protein Kinase into Xenopus oocytes by Maller, James L., Foulkes, J. Gordon, Erikson, Eleanor, Baltimore, David

“…Phosphorylation of ribosomal protein S6 in NIH 3T3 fibroblasts is dependent on the presence of serum, but after transformation of these cells by Abelson murine…”
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The broad specificity protein phosphatase from mammalian liver: Separation of the Mr 35 000 catalytic subunit into two distinct enzymes by Ingebritsen, Thomas S., Foulkes, J.Gordon, Cohen, Philip

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In vivo actions of protein phosphatase inhibitor-2 in Xenopus oocytes by Foulkes, J.Gordon, Maller, James L.

“…Meiotic maturation of amphibian oocytes induced by progesterone is known to be regulated by protein phosphorylation. To investigate a possible role for protein…”
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The hormonal control of glycogen metabolism. Phosphorylation of protein phosphatase inhibitor-1 in vivo in response to adrenaline by Foulkes, J G, Cohen, P

“…Inhibitor-1 has been shown to be phosphorylated in skeletal muscle in vivo. In normal fed animals the degree of phosphorylation was 31 +/- 7% and this value…”
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The Regulation of Glycogen Metabolism by FOULKES, J. Gordon, COHEN, Philip

“…Inhibitor‐2, a protein inhibitor of the multifunctional enzyme termed protein phosphatase‐1 [Cohen, P. (1978) Curr. Top. Cell. Regul. 14, 117‐196], was…”
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