Search Results - "FOULKES, J. G"

Identification of Another Member of the Transforming Growth Factor Type β Gene Family by Dijke, Peter Ten, Hansen, Pamela, Iwata, Kenneth K., Pieler, Christian, Foulkes, J. Gordon

“…We report here the complete amino acid sequence of another member of the type β transforming growth factor gene family, deduced from the nucleotide sequence of…”
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A novel abl protein expressed in Philadelphia chromosome positive acute lymphoblastic leukaemia by CHAN, L. C, KARHI, K. K, WIEDEMANN, L. M, RAYTER, S. I, HEISTERKAMP, N, ERIDANI, S, POWLES, R, LAWLER, S. D, GROFFEN, J, FOULKES, J. G, GREAVES, M. F

“…The Philadelphia (Ph) chromosome breakpoints in chronic myelocytic leukaemia are clustered on chromosome 22 band q11 in a 5.8-kilobase (kb) region designated…”
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Cell Lines and Peripheral Blood Leukocytes Derived from Individuals with Chronic Myelogenous Leukemia Display Virtually Identical Proteins Phosphorylated on Tyrosine Residues by Huhn, Richard D., Posner, Marshall R., Rayter, Sydonia I., Foulkes, J. Gordon, Frackelton, A. Raymond

“…An aberrant p210BCR-ABL protein that possesses constitutive protein-tyrosine kinase activity is presumed to be involved in the development of the neoplastic…”
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Purification and characterization of a protein-tyrosine kinase encoded by the Abelson murine leukemia virus by Foulkes, J G, Chow, M, Gorka, C, Frackelton, A R, Baltimore, D

“…Sequences termed v-abl, which encode the protein-tyrosine kinase activity of Abelson murine leukemia virus, have been expressed in Escherichia coli as a fusion…”
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Phosphorylation of Ribosomal Protein S6 on Serine after Microinjection of the Abelson Murine Leukemia Virus Tyrosine-Specific Protein Kinase into Xenopus oocytes by Maller, James L., Foulkes, J. Gordon, Erikson, Eleanor, Baltimore, David

“…Phosphorylation of ribosomal protein S6 in NIH 3T3 fibroblasts is dependent on the presence of serum, but after transformation of these cells by Abelson murine…”
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Sequences of the A-MuLV protein needed for fibroblast and lymphoid cell transformation by Prywes, R, Foulkes, J G, Rosenberg, N, Baltimore, D

“…The role of various segments (gag or v-abl) of the Abelson murine leukemia virus (A-MuLV) genome in both lymphoid cell and fibroblast transformation was…”
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Phosphatidylinositol turnover and transformation of cells by Abelson murine leukaemia virus by Fry, M.J., Gebhardt, A., Parker, P.J., Foulkes, J.G.

“…The transforming protein of the Abelson murine leukaemia virus encodes a protein‐tyrosine kinase. Previously, we have shown that in Abelson‐transformed cells,…”
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The minimum transforming region of v-abl is the segment encoding protein-tyrosine kinase by Prywes, R, Foulkes, J G, Baltimore, D

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Comprehensive essential gene identification as a platform for novel anti-infective drug discovery by Haselbeck, R, Wall, D, Jiang, B, Ketela, T, Zyskind, J, Bussey, H, Foulkes, J G, Roemer, T

“…In large part, antimicrobial drug discovery is driven by the breadth and quality of both potential drug targets and available chemical libraries to screen…”
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Separation of multiple phosphotyrosyl-and phosphoseryl-protein phosphatases from chicken brain by Foulkes, J G, Erikson, E, Erikson, R L

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Antagonistic effects of insulin and beta-adrenergic agonists on the activity of protein phosphatase inhibitor-1 in skeletal muscle of the perfused rat hemicorpus by Foulkes, J G, Cohen, P, Strada, S J, Everson, W V, Jefferson, L S

“…The extent of phosphorylation of protein phosphatase inhibitor-1 in skeletal muscle rose about 2.5-fold during 60 min of perfusion of the rat hemicorpus…”
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Separation and identification of type 1 and type 2 protein phosphatases from rabbit reticulocyte lysates by Foulkes, J G, Ernst, V, Levin, D H

“…Protein phosphatase type 1 and type 2 activities (designated PP-1 and PP-2, respectively) from rabbit reticulocyte lysates have been identified and…”
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The role of EGF receptor transmodulation in embryonal carcinoma‐derived growth factor‐induced mitogenesis by Heath, J.K., Mahadevan, L., Foulkes, J.G.

“…Exposure of quiescent 10T1/2 fibroblast cells to embryonal carcinoma‐derived growth factor (ECDGF) results in a rapid temperature and ECDGF…”
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Abelson transformed fibroblasts lacking the EGF receptor are not tumourigenic in nude mice by Gebhardt, A., Bell, J.C., Foulkes, J.G.

“…Cells transformed by the v‐abl‐oncogene produce large amounts of the tumour growth factor alpha TGF. alpha TGF is homologous to the epidermal growth factor…”
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A novel abl protein expressed in Philadelphia chromosome positive acute lymphoblastic leukaemia positive acute lymphoblastic leukaemia by Chan, L. C, Karhi, K. K, Rayter, S. I, Heisterkamp, N, Eridani, S, Powle, R, Lawler, S. D, Groffen, J, Foulkes, J. G, Greaves, M. F, Wiedemann, L. M

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Protein phosphatase-1 and -2A activities in heart, liver, and skeletal muscle extracts from control and diabetic rats by FOULKES, J. G, JEFFERSON, L. S

“…Protein phosphatase activities have recently been classified into two major groups of enzymes termed type 1 and type 2. In the present study, this…”
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Embryonal carcinoma‐derived growth factor activates protein kinase C in vivo and in vitro by Mahadevan, L.C., Aitken, A., Heath, J., Foulkes, J.G.

“…We have recently reported that a polypeptide mitogen, the embryonal carcinoma‐derived growth factor (ECDGF), induces phosphorylation of the epidermal growth…”
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Gene Expression as a Target for New Drug Discovery by HEGUY, ADRIANA, STEWART, ALEXANDER A., HALEY, JOHN D., SMITH, DAVID E., FOULKES, J. GORDON

“…Over the last 7 years we have carried out a major research effort focused on gene transcription as a novel approach to drug discovery. The goal is to identify…”
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Phosphotyrosyl-protein phosphatases by Foulkes, J G

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Abelson-transformed fibroblasts contain nuclear phosphotyrosyl-proteins which preferentially bind to murine DNA by Bell, John C, Mahadevan, Louis C, Colledge, William H, Frackelton, A. Raymond, Sargent, Michael G, Foulkes, J. Gordon

“…Protein-tyrosine kinases, either in the form of growth-factor receptors or as the polypeptide products of oncogenes, appear to be important in the regulation…”
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