Search Results - "FOUGEREAU, M"

The SH3 Domain of Bruton's Tyrosine Kinase Interacts with Vav, Sam68 and EWS by GUINAMARD, R., FOUGEREAU, M., SECKINGER, P.

“…Bruton tyrosine kinase (BTK) is a cytoplasmic protein tyrosine kinase which controls crucial steps of differentiation of B lymphocytes. Mutations affecting…”
Get full text

A human non-XLA immunodeficiency disease characterized by blockage of B cell development at an early proB cell stage by Meffre, E, LeDeist, F, de Saint-Basile, G, Deville, A, Fougereau, M, Fischer, A, Schiff, C

“…We report a detailed analysis of a B cell defect affecting a patient girl born from first cousin parents, characterized by a severe non-X-linked…”
Get full text

Construction of temperature and Zn-dependent human stromal cell lines that amplify hematopoietic precursors from cord blood CD34+ cells by Gauthier, L, Fougereau, M, Tonnelle, C

“…Forty-five human stromal cell lines were established from long-term bone marrow cultures transformed with a new vector, pNu MTSVts, which contains the…”
Get more information

Two V kappa germ-line genes related to the GAT idiotypic network (Ab1 and Ab3/Ab1') account for the major subfamilies of the mouse V kappa-1 variability subgroup by Corbet, S, Milili, M, Fougereau, M, Schiff, C

“…V kappa Ig germ-line genes have been isolated from recombinant clones prepared in separate libraries constructed from adult BALB/c liver DNA. Three different…”
Get full text

Preferential expression of VH5 and VH6 immunoglobulin genes in early human B-cell ontogeny by Cuisinier, A M, Guigou, V, Boubli, L, Fougereau, M, Tonnelle, C

“…Analysis of Ig transcripts by dot blot hybridization revealed that VH5 and VH6 RNA first occurred during the 7th week of gestation in human fetal liver. At the…”
Get more information

Functional and pseudogenes are similarly organized and may equally contribute to the extensive antibody diversity of the IgVHII family by Schiff, C., Milili, M., Fougereau, M.

“…Eleven germ‐line immunoglobulin VH genes have been isolated from a BALB/c genomic library, using a cDNA probe specific for the GAT/NPa variable region…”
Get full text

The human pre-B cell receptor: structural constraints for a tentative model of the pseudo-light (psi L) chain by Guelpa-Fonlupt, V, Bossy, D, Alzari, P, Fumoux, F, Fougereau, M, Schiff, C

“…In human pre-B cells, the mu chain is associated with a surrogate light chain composed of the lambda-like and Vpre-B gene products. This pre-B cell receptor…”
Get more information

Composite exon structure of an unusual Ig lambda-like gene located at human 22q11 position by Schiff, C, Milili, M, Zucman-Rossi, J, Djabali, M, Fougereau, M

“…The surrogate light chain, composed of the VpreB and the lambda-like proteins, plays a critical role in controlling the early stages of B lymphocyte…”
Get full text

A non-XLA primary deficiency causes the earliest known defect of B cell differentiation in humans: a comparison with an XLA case by Meffre, E, LeDeist, F, de Saint-Basile, G, Deville, A, Fougereau, M, Fischer, A, Schiff, C

“…We report a detailed comparison of B cell defects in two patients, one XLA and one non-XLA. Both had severe agammaglobulinemia with a total absence of CD19 +…”
Get full text

Individual germinal centres of myasthenia gravis human thymuses contain polyclonal activated B cells that express all the VH and VK families by GUIGOU, V., EMILIE, D., BERRIH‐AKNIN, S., FUMOUX, F., FOUGEREAU, M., SCHIFF, C.

“…SUMMARY Using in situ hybridization, we analysed the immunoglobulin repertoire expressed by the B cells present in myasthenia gravis thymuses from four…”
Get full text

The idiotypic network and the internal image: possible regulation of a germ‐line network by paucigene encoded Ab2 (anti‐idiotypic) antibodies in the GAT system by Ollier, P., Rocca‐Serra, J., Sommé, G., Thèze, J., Fougereau, M.

“…Heavy and light chain variable regions from eight monoclonal Ab2 (anti‐idiotypic) antibodies of the GAT antigen, a (Glu60 Ala30 Tyr10)n co‐polymer, have been…”
Get full text

Activation of clones producing self-reactive antibodies by foreign antigen and antiidiotype antibody carrying the internal image of the antigen by BAILEY, N. C, FIDANZA, V, MAYER, R, MAZZA, G, FOUGEREAU, M, BONA, C

“…Because we found in previous work that a high fraction of antibodies exhibiting various specificities bound to glutamic acid 50-tyrosine50 homopolymer (GT) and…”
Get full text

Allogeneic manipulation of the GAT idiotypic cascade. Immunization of C57BL/6 mice by BALB/c anti-idiotypes stimulates similar strain- specific V genes as the original antigen by Corbet, S, Hirn, M, Roth, C, Theze, J, Fougereau, M, Schiff, C

“…Antibodies specific for the immunizing Ag (Ab1) (Id+ Ag+) and Ab3 (Id+ Ag+ or Id+ Ag-) of the (Glu60 Tyr10 Ala30) (GAT) idiotypic cascade express similar pGAT…”
Get full text

Analysis of antibody diversity: V‐D‐J mRNA nucleotide sequence of four anti‐GAT monoclonal antibodies. A paucigene system using alternate D‐J recombinations to generate functionally similar hypervariable regions by Rocca‐Serra, J., Matthes, H.W., Kaartinen, M., Milstein, C., Thèze, J., Fougereau, M.

“…The nucleotide sequence of four anti‐(Glu60‐Ala30‐Tyr10)n (GAT) monoclonal gamma 1 heavy chain mRNAs was determined from codon 10 to 120. This sequence…”
Get full text

Interstrain conservation of the murine GAT‐specific antibody V kappa repertoire as analyzed at the germline gene level by Schiff, C., Corbet, S., Milili, M., Fougereau, M.

“…A cDNA library was constructed in pBR322 from mRNA encoding an anti‐GAT (Glu60 Ala30 Tyr10) monoclonal antibody kappa chain. Two cDNA clones were extensively…”
Get full text

Partial amino acid sequence of two forms of human post-gamma-globulin by Tonnelle, C, Colle, A, Fougereau, M, Manuel, Y

Get more information

Structural Bases for public Idiotypic Specificities of Monoclonal Antibodies Directed against poly(Glu60Ala30Tyr10) and poly(Glu60Ala40) Random Copolymers by Ruf, Jean, Tonnelle, Cecile, Rocca-Serra, Jose, Moinier, Danielle, Pierres, Michel, Ju, Shyr-Te, Dorf, Martin E., Theze, Jacques, Fougereau, Michel

“…NH2-terminal amino acid sequences of heavy and light chains of seven poly(Glu60Ala30Tyr10) (GAT) specific hybridoma products derived from DBA/2 and (DBA/2 ×…”
Get full text

The limited diversity of the mouse gamma-chains anti-GAT repertoire does not seem to be noticeably amplified upon class switch by Rocca-Serra, J, Mazie, JC, Moinier, D, Leclercq, L, Somme, G, Theze, J, Fougereau, M

“…NH2-terminal sections of H and L chains isolated from five monoclonal anti-GAT antibodies derived from BALB/c mice have been sequenced upon to residue 43. Four…”
Get full text

Repertoire of the anti-MOPC 173 anti-idiotypic antibodies: genetical and structural features by Boyer, C, Schiff, C, Milili, M, Fougereau, M

Get more information

IgH repertoire and Ig-related gene expression in X-linked agammaglobulinemia by Schiff, C, Milili, M, Le Deist, F, De Saint-Basile, G, Fischer, A, Fougereau, M

Get more information