Search Results - "FOUCHET, Pierre"
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1
EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells
Published in Nature communications (26-08-2019)“…The Polycomb group of proteins is required for the proper orchestration of gene expression due to its role in maintaining transcriptional silencing. It is…”
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2
Competition for Food Drives Stem Cell Fate in Facultative Niches
Published in Cell stem cell (03-01-2019)“…Mechanisms regulating maintenance of the stem cell pool in facultative niches of the mammalian testis are poorly understood. In this issue of Cell Stem Cell,…”
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3
Revealing cellular and molecular transitions in neonatal germ cell differentiation using single cell RNA sequencing
Published in Development (Cambridge) (27-03-2019)“…Neonatal germ cell development provides the foundation of spermatogenesis. However, a systematic understanding of this process is still limited. To resolve…”
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4
Mouse differentiating spermatogonia can generate germinal stem cells in vivo
Published in Nature cell biology (01-02-2009)“…In adults, stem cells are responsible for the maintenance of many actively renewing tissues, such as haematopoietic, skin, gut and germinal tissues. These stem…”
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5
The netrin-1 receptor UNC5C contributes to the homeostasis of undifferentiated spermatogonia in adult mice
Published in Stem cell research (01-04-2022)“…•The Netrin-1 receptor UNC5c is expressed in undifferentiated spermatogonia.•Loss of Unc5c impairs the differentiation of spermatogonia.•Phenotype worsens with…”
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6
Contribution of Single-Cell Transcriptomics to the Characterization of Human Spermatogonial Stem Cells: Toward an Application in Male Fertility Regenerative Medicine?
Published in International journal of molecular sciences (16-11-2019)“…Ongoing progress in genomic technologies offers exciting tools that can help to resolve transcriptome and genome-wide DNA modifications at single-cell…”
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7
In vivo cellular imaging pinpoints the role of reactive oxygen species in the early steps of adult hematopoietic reconstitution
Published in Blood (21-01-2010)“…Few techniques are available to characterize in vivo the early cellular dynamics of long-term reconstitution of hematopoiesis after transplantation of…”
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8
Flow cytometric characterization of viable meiotic and postmeiotic cells by Hoechst 33342 in mouse spermatogenesis
Published in Cytometry. Part A (01-05-2005)“…Background Spermatogenesis in adult is a complex stepwise process leading to terminally differentiated spermatozoa. The cellular heterogeneity of testis…”
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Side Population' cells in adult mouse testis express Bcrp1 gene and are enriched in spermatogonia and germinal stem cells
Published in Development (Cambridge) (01-01-2004)“…Stem cells in various somatic tissues (bone marrow, skeletal muscle) can be identified by the `Side Population' marker based on Hoechst 33342 efflux. We show…”
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10
Puma and Trail/Dr5 pathways control radiation-induced apoptosis in distinct populations of testicular progenitors
Published in PloS one (12-08-2010)“…Spermatogonia- stem cells and progenitors of adult spermatogenesis- are killed through a p53-regulated apoptotic process after gamma-irradiation but the death…”
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11
Fanconi DNA repair pathway is required for survival and long-term maintenance of neural progenitors
Published in The EMBO journal (05-03-2008)“…Although brain development abnormalities and brain cancer predisposition have been reported in some Fanconi patients, the possible role of Fanconi DNA repair…”
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12
Impaired functionality and homing of Fancg-deficient hematopoietic stem cells
Published in Human molecular genetics (01-01-2012)“…Fanconi anemia (FA) is a human rare genetic disorder characterized by congenital defects, bone marrow (BM) failure and predisposition to leukemia. The…”
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13
Similarities and Differences in the In Vivo Response of Mouse Neonatal Gonocytes and Spermatogonia to Genotoxic Stress
Published in Biology of reproduction (01-05-2009)“…Neonatal gonocytes are the precursors of both spermatogonial stem cells and spermatogonia; thus, any persistant DNA damage in these cells may lead to heritable…”
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14
Neural stem cells from mouse forebrain are contained in a population distinct from the ‘side population’
Published in Journal of neurochemistry (01-11-2006)“…Developing and adult forebrains contain neural stem cells (NSCs) but no marker is available to highly purify them. When analysed by flow cytometry, stem cells…”
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15
Role of Fanconi DNA repair pathway in neural stem cell homeostasis
Published in Cell cycle (Georgetown, Tex.) (01-07-2008)“…Defects in DNA repair pathways have been involved in collapse of early neurogenesis leading to brain development abnormalities and embryonic lethality…”
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16
Similarities and Differences in the In Vivo Response of Mouse Neonatal Gonocytes and Spermatogonia to Genotoxic Stress1
Published in Biology of reproduction (01-05-2009)“…Neonatal gonocytes are the precursors of both spermatogonial stem cells and spermatogonia; thus, any persistant DNA damage in these cells may lead to heritable…”
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17
The Telomerase Activity of Adult Mouse Testis Resides in the Spermatogonial α6-Integrin-Positive Side Population Enriched in Germinal Stem Cells
Published in Endocrinology (Philadelphia) (01-09-2005)“…Testis is one of the organs with the most telomerase activity in the adult. This activity protects chromosomes from telomere attrition and ensures the…”
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18
Origin of the complex karyotype of the polyploid parthenogenetic grasshopper Saga pedo (Orthoptera: Tettigoniidae)
Published in European journal of entomology (01-01-2009)“…Karyotypes of the polyploid parthenogenetic species Saga pedo from four localities in France and the Republic of Macedonia were constructed and compared. All…”
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DNMT3A-dependent DNA methylation is required for spermatogonial stem cells to commit to spermatogenesis
Published in Nature genetics (01-04-2022)“…DNA methylation plays a critical role in spermatogenesis, as evidenced by the male sterility of DNA methyltransferase (DNMT) mutant mice. Here, we report a…”
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20
Fine deletion mapping of chromosome 8p in non‐small‐cell lung carcinoma
Published in International journal of cancer (11-06-1999)“…Several somatic genetic alterations have been described in non‐small‐cell lung carcinomas (NSCLC). Recurrent chromosomal deletions have suggested the presence…”
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