Search Results - "FORTES, Zuleica B"

Metformin induces apoptosis and cell cycle arrest mediated by oxidative stress, AMPK and FOXO3a in MCF-7 breast cancer cells by Queiroz, Eveline A I F, Puukila, Stephanie, Eichler, Rosangela, Sampaio, Sandra C, Forsyth, Heidi L, Lees, Simon J, Barbosa, Aneli M, Dekker, Robert F H, Fortes, Zuleica B, Khaper, Neelam

“…Recent studies have demonstrated that the anti-diabetic drug, metformin, can exhibit direct antitumoral effects, or can indirectly decrease tumor proliferation…”
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Toll-like receptor 4 contributes to blood pressure regulation and vascular contraction in spontaneously hypertensive rats by Bomfim, Gisele F, Dos Santos, Rosangela A, Oliveira, Maria Aparecida, Giachini, Fernanda R, Akamine, Eliana H, Tostes, Rita C, Fortes, Zuleica B, Webb, R Clinton, Carvalho, Maria Helena C

“…Activation of TLRs (Toll-like receptors) induces gene expression of proteins involved in the immune system response. TLR4 has been implicated in the…”
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Testosterone Induces Vascular Smooth Muscle Cell Migration by NADPH Oxidase and c-Src–Dependent Pathways by Chignalia, Andreia Z, Schuldt, Elke Z, Camargo, Lívia L, Montezano, Augusto C, Callera, Gláucia E, Laurindo, Francisco R, Lopes, Lucia R, Avellar, Maria Christina W, Carvalho, Maria Helena C, Fortes, Zuleica B, Touyz, Rhian M, Tostes, Rita C

“…Testosterone has been implicated in vascular remodeling associated with hypertension. Molecular mechanisms underlying this are elusive, but oxidative stress…”
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Testosterone induces leucocyte migration by NADPH oxidase-driven ROS- and COX2-dependent mechanisms by Chignalia, Andreia Z, Oliveira, Maria Aparecida, Debbas, Victor, Dull, Randal O, Laurindo, Francisco R M, Touyz, Rhian M, Carvalho, Maria Helena C, Fortes, Zuleica B, Tostes, Rita C

“…The mechanisms whereby testosterone increases cardiovascular risk are not clarified. However, oxidative stress and inflammation seem to be determinants…”
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An interaction of renin-angiotensin and kallikrein-kinin systems contributes to vascular hypertrophy in angiotensin II-induced hypertension: in vivo and in vitro studies by Ceravolo, Graziela S, Montezano, Augusto C, Jordão, Maria T, Akamine, Eliana H, Costa, Tiago J, Takano, Ana P, Fernandes, Denise C, Barreto-Chaves, Maria L, Laurindo, Francisco R, Tostes, Rita C, Fortes, Zuleica B, Chopard, Renato P, Touyz, Rhian M, Carvalho, Maria Helena C

“…The kallikrein-kinin and renin-angiotensin systems interact at multiple levels. In the present study, we tested the hypothesis that the B1 kinin receptor (B1R)…”
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Reduced endothelium-dependent relaxation to anandamide in mesenteric arteries from young obese Zucker rats by Lobato, Nubia S, Filgueira, Fernando P, Prakash, Roshini, Giachini, Fernanda R, Ergul, Adviye, Carvalho, Maria Helena C, Webb, R Clinton, Tostes, Rita C, Fortes, Zuleica B

“…Impaired vascular function, manifested by an altered ability of the endothelium to release endothelium-derived relaxing factors and endothelium-derived…”
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Endothelin, sex and hypertension by Tostes, Rita C, Fortes, Zuleica B, Callera, Glaucia E, Montezano, Augusto C, Touyz, Rhian M, Webb, R Clinton, Carvalho, Maria Helena C

“…The ETs (endothelins) comprise a family of three 21-amino-acid peptides (ET-1, ET-2 and ET-3) and 31-amino-acid ETs (ET-1(1-31), ET-2(1-31) and ET-3(1-31))…”
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Upregulation of ERK1/2-eNOS via AT2 receptors decreases the contractile response to angiotensin II in resistance mesenteric arteries from obese rats by Hagihara, Graziela N, Lobato, Nubia S, Filgueira, Fernando P, Akamine, Eliana H, Aragão, Danielle S, Casarini, Dulce E, Carvalho, Maria Helena C, Fortes, Zuleica B

“…It has been clearly established that mitogen-activated protein kinases (MAPKS) are important mediators of angiotensin II (Ang II) signaling via AT1 receptors…”
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STIM1/Orai1 contributes to sex differences in vascular responses to calcium in spontaneously hypertensive rats by Giachini, Fernanda R C, Lima, Victor V, Filgueira, Fernando P, Dorrance, Anne M, Carvalho, Maria Helena C, Fortes, Zuleica B, Webb, R Clinton, Tostes, Rita C

“…Sex differences in Ca2+-dependent signalling and homoeostasis in the vasculature of hypertensive rats are well characterized. However, sex-related differences…”
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Long-term effects of maternal diabetes on vascular reactivity and renal function in rat male offspring by ROCHA, Silvia O, GOMES, Guiomar N, FORTI, André Luis L, DO CARMO PINHO FRANCO, Maria, FORTES, Zuleica B, DE FATIMA CAVANAL, Maria, ZALADEK GIL, Frida

“…Fetal growth impairment can occur in pregnancy complicated by diabetes. Although several studies have focused the effects of nutritional status on intrauterine…”
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In Vivo Evidence for Antioxidant Potential of Estrogen in Microvessels of Female Spontaneously Hypertensive Rats by Dantas, Ana Paula V, Tostes, Rita C.A, Fortes, Zuleica B, Costa, Sonia G, Nigro, Dorothy, Carvalho, Maria Helena C

“…In studies conducted in vitro, it has been demonstrated that estrogen has an antioxidant potential that may contribute to its protective effects on the…”
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Long-term effects of intrauterine malnutrition on vascular function in female offspring: Implications of oxidative stress by Franco, Maria C.P., Akamine, Eliana H., Rebouças, Nancy, Carvalho, Maria Helena C., Tostes, Rita C.A., Nigro, Dorothy, Fortes, Zuleica B.

“…Maternal malnutrition is known to impair fetal growth and predispose to the development of hypertension and type 2 diabetes. Recently, studies have…”
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Influence of age on the development of immunological lung response in intrauterine undernourishment by Landgraf, Maristella A., Ph.D, Landgraf, Richardt G., Ph.D, Jancar, Sonia, Fortes, Zuleica B., Ph.D

“…Abstract Objective We investigated the effect of intrauterine undernourishment on some features of asthma using a model of allergic lung inflammation in rats…”
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Antiproliferative and pro-apoptotic effects of three fungal exocellular β-glucans in MCF-7 breast cancer cells is mediated by oxidative stress, AMP-activated protein kinase (AMPK) and the Forkhead transcription factor, FOXO3a by Queiroz, Eveline A.I.F., Fortes, Zuleica B., da Cunha, Mário A.A., Barbosa, Aneli M., Khaper, Neelam, Dekker, Robert F.H.

“…•β-Glucans presented antiproliferative and pro-apoptotic effects against MCF-7 cells.•The degree of branching and triple helix conformation contributed to the…”
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Levan promotes antiproliferative and pro-apoptotic effects in MCF-7 breast cancer cells mediated by oxidative stress by Queiroz, Eveline A.I.F., Fortes, Zuleica B., da Cunha, Mário A.A., Sarilmiser, Hande Kazak, Barbosa Dekker, Aneli M., Öner, Ebru Toksoy, Dekker, Robert F.H., Khaper, Neelam

“…Exopolysaccharides are high-valued bio-products produced by various microbial species and have been described to possess biological response modifying…”
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Tetrahydrobiopterin improves endothelial dysfunction and vascular oxidative stress in microvessels of intrauterine undernourished rats by Franco, Maria do Carmo P., Fortes, Zuleica B., Akamine, Eliana H., Kawamoto, Elisa M., Scavone, Cristoforo, De Britto, Luiz Roberto Giorgetti, Muscara, Marcelo N., Teixeira, Simone A., Tostes, Rita C. A., Carvalho, Maria Helena C., Nigro, Dorothy

“…In the present study, we investigated the effects of the exogenous application of tetrahydrobiopterin on the endothelium-dependent vasorelaxation and…”
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Mechanisms involved in the reduced leukocyte migration in intrauterine undernourishment by Landgraf, Maristella A., Ph.D, Tostes, Rita de C.A., Ph.D, Borelli, Primavera, Ph.D, Zorn, Telma Maria Tenório, Ph.D, Nigro, Dorothy, Ph.D, Carvalho, Maria Helena C., Ph.D, Fortes, Zuleica B., Ph.D

“…Abstract Objective We investigated factors that may be involved in the reduced leukocyte migration observed in intrauterine undernourished rats. Methods Male…”
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Ovarian Hormones Modulate Endothelin-1 Vascular Reactivity and mRNA Expression in DOCA-Salt Hypertensive Rats by David, Flavia L, Carvalho, Maria Helena C, Cobra, Ana L.N, Nigro, Dorothy, Fortes, Zuleica B, Rebouças, Nancy A, Tostes, Rita C.A

“…We previously demonstrated a differential activation of the endothelin-1 (ET-1) pathway in male and female deoxycorticosterone (DOCA)-salt hypertensive rats,…”
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Association of testosterone with estrogen abolishes the beneficial effects of estrogen treatment by increasing ROS generation in aorta endothelial cells by Costa, Tiago J, Ceravolo, Graziela S, dos Santos, Rosangela A, de Oliveira, Maria Aparecida, Araújo, Priscila X, Giaquinto, Luciana R, Tostes, Rita C, Akamine, Eliana H, Fortes, Zuleica B, Dantas, Ana Paula, Carvalho, Maria Helena C

“…Testosterone has been added to hormone replacement therapy to treat sexual dysfunction in postmenopausal women. Whereas estrogen has been associated with…”
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O-GlcNAcylation contributes to the vascular effects of ET-1 via activation of the RhoA/Rho-kinase pathway by LIMA, Victor V, GIACHINI, Fernanda R, CARNEIRO, Fernando S, CARVALHO, Maria Helena C, FORTES, Zuleica B, CLINTON WEBB, R, TOSTES, Rita C

“…Glycosylation with β-N-acetylglucosamine (O-GlcNAcylation) is one of the most complex post-translational modifications. The cycling of O-GlcNAc is controlled…”
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