Search Results - "FOROOZESH, M"

QSAR models of cytochrome P450 enzyme 1A2 inhibitors using CoMFA, CoMSIA and HQSAR by Sridhar, J., Foroozesh, M., Stevens, C.L. Klein

“…Quantitative structure-activity relationship (QSAR) studies were conducted on an in-house database of cytochrome P450 enzyme 1A2 inhibitors using the…”
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Preparation and in vitro evaluation of carrier erythrocytes for RES-targeted delivery of interferon-alpha 2b by Hamidi, M., Zarrin, A.H., Foroozesh, M., Zarei, N., Mohammadi-Samani, S.

“…Carrier erythrocytes is one of the most promising systemic drug delivery systems investigated in recent decades. In this study, human erythrocytes have been…”
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Suicide inhibitors of cytochrome P450 1A1 and P450 2B1 by Hopkins, N E, Foroozesh, M K, Alworth, W L

“…The inhibition of the P450 1A1 dependent de-ethylation of 7-ethoxyphenoxazone (7EPO) and the P450 2B1 dependent de-pentylation of 7-pentoxyphenoxazone (7PPO)…”
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Preparation and in-vitro characterization of tramadol-loaded carrier erythrocytes for long-term intravenous delivery by Foroozesh, Mahshid, Hamidi, Mehrdad, Zarrin, Adbolhossein, Mohammadi-Samani, Soliman, Montaseri, Hashem

“…Objectives  The hypo‐osmotic dialysis method was used for preparation of tramadol‐loaded human intact erythrocytes. In response to rapid drug escape from the…”
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Metabolic fate of the Ah receptor ligand 6-formylindolo[3,2- b]carbazole by Bergander, Linda, Wincent, Emma, Rannug, Agneta, Foroozesh, Maryam, Alworth, William, Rannug, Ulf

“…The physiological role of the aryl hydrocarbon receptor (AhR), a member of the basic helix–loop–helix PER-ARNT-SIM (PAS) transcription factor family is not…”
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Selectivity of Polycyclic Inhibitors for Human Cytochrome P450s 1A1, 1A2, and 1B1 by Shimada, Tsutomu, Yamazaki, Hiroshi, Foroozesh, Maryam, Hopkins, Nancy E, Alworth, William L, Guengerich, F. Peter

“…Human cytochrome P450s 1A1, 1A2, and 1B1 are known to have overlapping substrate specificities. All are regulated in part by the Ah locus; P450 1A2 is…”
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A simple and rapid HPLC method for quantitation of interferon-α2b in dosage forms and delivery systems by Zarrin, Abdolhossein, Foroozesh, Mahshid, Hamidi, Mehrdad, Mohammadi-Samani, Soleyman

“…Development of reliable assay methods for quantitation of interferons in dosage forms has encountered serious limitations because of the physicochemical nature…”
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Identification of selective mechanism-based inactivators of cytochromes P-450 2B4 and 2B5, and determination of the molecular basis for differential susceptibility by Strobel, S M, Szklarz, G D, He, Y, Foroozesh, M, Alworth, W L, Roberts, E S, Hollenberg, P F, Halpert, J R

“…Rabbit cytochromes P-450 (P-450) 2B4 and 2B5 differ by only 12 amino acid residues yet they exhibit unique steroid hydroxylation profiles. Previous studies…”
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Metabolism-Based Polycyclic Aromatic Acetylene Inhibition of CYP1B1 in 10T1/2 Cells Potentiates Aryl Hydrocarbon Receptor Activity by Alexander, David L., Zhang, Leying, Foroozesh, Maryam, Alworth, William L., Jefcoate, Colin R.

“…We have used polycyclic aromatic hydrocarbon (PAH) alkyne metabolism-based inhibitors to test whether CYP1B1 metabolism is linked to aryl hydrocarbon receptor…”
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Antimycobacterial Activities of Dehydrocostus Lactone and Its Oxidation Products by Cantrell, Charles L, Nuñez, Isabel S, Castañeda-Acosta, José, Foroozesh, Maryam, Fronczek, Frank R, Fischer, Nikolaus H, Franzblau, Scott G

“…In an attempt to study the structural dependence of antimycobacterial activity of the guaianolide dehydrocostus lactone and its derivatives,…”
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Inactivation of Cytochrome P450s 2B1, 2B4, 2B6, and 2B11 by Arylalkynes by ROBERTS, E. S, HOPKINS, N. E, FOROOZESH, M, ALWORTH, W. L, HALPERT, J. R, HOLLENBERG, P. F

“…The time-dependent loss of the 7-ethoxy-4-trifluoromethylcoumarin (EFC) O -deethylase activity of rat P450 2B1, rabbit P450 2B4, or dog P450 2B11 by…”
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Aryl Acetylenes as Mechanism-Based Inhibitors of Cytochrome P450-Dependent Monooxygenase Enzymes by Foroozesh, Maryam, Primrose, Ginny, Guo, Zuyu, Bell, L. Chastine, Alworth, William L, Guengerich, F. Peter

“…Aryl acetylenes have been investigated as inhibitors of cytochrome P450 (P450)-dependent alkoxyresorufin dealkylation activities in liver microsomes prepared…”
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Inhibition of Cytochrome P450 6D1 by Alkynylarenes, Methylenedioxyarenes, and Other Substituted Aromatics by Scott, Jeffrey G., Foroozesh, Maryam, Hopkins, Nancy E., Alefantis, Timothy G., Alworth, William L.

“…We evaluated 33 compounds, comprising five different structural groups (alkynylpyrenes, alkynylphenanthrenes, methylenedioxyarenes, flavones, and…”
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Release of iron from ferritin by aqueous extracts of cigarette smoke by Moreno, Juan J, Foroozesh, Mahtab, Church, Daniel F, Pryor, William A

“…This study demonstrates the ability of aqueous extracts of cigarette smoke to reduce iron and cause its release from ferritin. Superoxide dismutase (SOD)…”
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Multisystem Organ Failure in the Setting of Systemic Vasculitis: Nonmedical Silicone Injections and Autoimmune/Inflammatory Syndrome Induced by Adjuvants (ASIA) by Pelleg, Tomer, DO, Siddiqui, Faisal, MD, Ie, Susanti, MD, Rubio, Edmundo, MD, Foroozesh, Mahtab, MD

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Decreasing Use of Continuous Sedation in the ICU: Identifying Obstacles to Adopting a Protocol by Sahebazamani, Mitra, MD, Bond, Donna, RN, Osborne, Lisha, RN, Goodwin, Corey, PharmD, Foroozesh, Mahtab, MD

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Aryl acetylene inhibitors for cytochrome P450-based monooxygenase isozymes by MAGUE, J. T, FOROOZESH, M, HOPKINS, N. E, GAN, L. L.-S, ALWORTH, W. L

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