Search Results - "FORMAN, S. A"

Etomidate produces similar allosteric modulation in α1β3δ and α1β3γ2L GABAA receptors by Feng, H‐J, Jounaidi, Y, Haburcak, M, Yang, X, Forman, S A

“…Background and Purpose Neuronal GABAA receptors are pentameric chloride ion channels, which include synaptic αβγ and extrasynaptic αβδ isoforms, mediating…”
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A discrete site for general anesthetics on a postsynaptic receptor by Forman, S A, Miller, K W, Yellen, G

“…General anesthetics depress central nervous system excitability via a mechanism that probably involves effects on synaptic ion channels, but the fundamental…”
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The n-Alcohol Site in the Nicotinic Receptor Pore Is a Hydrophobic Patch by Zhou, Qiong L, Zhou, Qing, Forman, Stuart A

“…Alcohols and volatile anesthetics inhibit peripheral nicotinic acetylcholine receptors noncompetitively, primarily via an open-channel block mechanism…”
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Lack of benefit from percutaneous intervention of persistently occluded infarct arteries after the acute phase of myocardial infarction is time independent: insights from Occluded Artery Trial by Menon, Venu, Pearte, Camille A., Buller, Christopher E., Steg, Ph.Gabriel, Forman, Sandra A., White, Harvey D., Marino, Paolo N., Katritsis, Demosthenes G., Caramori, Paulo, Lasevitch, Ricardo, Loboz-Grudzien, Krystyna, Zurakowski, Aleksander, Lamas, Gervasio A., Hochman, Judith S.

“…Aims The Occluded Artery Trial (OAT) (n = 2201) showed no benefit for routine percutaneous intervention (PCI) (n = 1101) over medical therapy (MED) (n = 1100)…”
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Synthesis and Properties of 3-(2-Hydroxyethyl)-3-n-pentyldiazirine, a Photoactivable General Anesthetic by Husain, S. Shaukat, Forman, Stuart A, Kloczewiak, Marek A, Addona, George H, Olsen, Richard W, Pratt, Megan B, Cohen, Jonathan B, Miller, Keith W

“…To overcome the difficulties of locating the molecular sites of general anesthetic action, we synthesized a novel photoactivable general anesthetic,…”
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Short chain and long chain alkanols have different sites of action on nicotinic acetylcholine receptor channels from Torpedo by Wood, S C, Forman, S A, Miller, K W

“…At nicotinic acetylcholine receptors, short chain n-alcohols (alkanols) have excitatory actions, whereas long chain alkanols inhibit channel activity. This…”
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Nonanesthetic volatile drugs obey the meyer-overton correlation in two molecular protein site models by FORMAN, S. A, RAINES, D. E

“…Nonanesthetic volatile compounds fail to inhibit movement in response to noxious stimulation at concentrations predicted to induce anesthesia from their…”
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Long-term effects on Clinical outcomes of aggressive lowering of low-density lipoprotein cholesterol levels and low-dose anticoagulation in the Post Coronary Artery Bypass Graft Trial by KNATTERUD, G. L, ROSENBERG, Y, HOOGWERF, B. J, TERRIN, M. L, WHITE, C, CAMPEAU, L, GELLER, N. L, HUNNINGHAKE, D. B, FORMAN, S. A, FORRESTER, J. S, GOBEL, F. L, HERD, J. A, HICKEY, A

“…Background —The Post Coronary Artery Bypass Graft Trial, designed to compare the effects of 2 lipid-lowering regimens and low-dose anticoagulation versus…”
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Thrombolysis in myocardial infarction (TIMI): Comparative studies of coronary reperfusion and systemic fibrinogenolysis with two forms of recombinant tissue-type plasminogen activator by Mueller, Hiltrud S., Koneti Rao, A., Forman, Sandra A.

“…Coronary recanalization rates and changes in plasma proteins of the fibrinolytic system were evaluated with two preparations of recombinant tissue-type…”
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Actions of pentobarbital enantiomers on nicotinic cholinergic receptors by Roth, S H, Forman, S A, Braswell, L M, Miller, K W

“…The enantiomers of pentobarbital had four different actions on the nicotinic receptor-rich membranes from Torpedo electroplaques. (i) Both inhibited…”
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Stereoselectivity of channel inhibition by secondary alkanol enantiomers at nicotinic acetylcholine receptors by ALIFIMOFF, J. K, BUGGE, B, FORMAN, S. A, MILLER, K. W

“…At the nicotinic acetylcholine receptor, long chain alkanols reduce, whereas short chain alkanols augment endplate currents. Using the enantiomers of five…”
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High acetylcholine concentrations cause rapid inactivation before fast desensitization in nicotinic acetylcholine receptors from Torpedo by Forman, S.A., Miller, K.W.

“…By using both a 3 to 4 ms quenched-86Rb+ flux assay and native acetylcholine receptor (AChR) rich electroplaque vesicles on which 50–60% of acetylcholine…”
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Alternative mechanism for pathogenesis of an inherited epilepsy by a nicotinic AChR mutation by Forman, Stuart A, Yellen, Gary, Thiele, Elizabeth A

“…In a recent article on the genetic basis of autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE), Steinlein and colleagues described a missense mutation…”
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Ethanol increases agonist affinity for nicotinic receptors from Torpedo by Forman, S A, Righi, D L, Miller, K W

“…The presence of ethanol increases the apparent affinity with which acetylcholine and carbamylcholine elicit 86Rb+ flux from Torpedo nicotinic acetylcholine…”
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Influence of coronary collateral vessels on myocardial infarct size in humans : results of phase I thrombolysis in myocardial infarction (TIMI) trial by HABIB, G. B, HEIBIG, J, FORMAN, S. A, BROWN, B. G, ROBERTS, R, TERRIN, M. L, BOLLI, R

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Nonhalogenated alkane anesthetics fail to potentiate agonist actions on two ligand-gated ion channels by RAINES, Douglas E, CLAYCOMB, Robert J, SCHELLER, Michaela, FORMAN, Stuart A

“…Although ether, alcohol, and halogenated alkane anesthetics potentiate agonist actions or increase the apparent agonist affinity of ligand-gated ion channels…”
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'Dust and Mirrors' or 'Corruption is in the eye of the beholder' by Borron, Stephen W., Forman, Samuel A., Lockey, James E., Lemasters, Grace K., Yee, Leslie M.

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A Hydrophobic Photolabel Inhibits Nicotinic Acetylcholine Receptors via Open-Channel Block Following a Slow Step by Forman, Stuart A

“…3-(Trifluoromethyl)-3-(m-iodophenyl)diazirine (TID) is a hydrophobic inhibitor of nicotinic acetylcholine receptors (nAChRs) and a photolabel that incorporates…”
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Aggressive cholesterol lowering delays saphenous vein Graft atherosclerosis in women, the elderly, and patients with associated risk factors: NHLBI Post Coronary Artery Bypass Graft clinical trial by CAMPEAU, L, HUNNINGHAKE, D. B, HOOGWERF, B. J, ROSENBERG, Y, KNATTERUD, G. L, WHITE, C. W, DOMANSKI, M, FORMAN, S. A, FORRESTER, J. S, GELLER, N. L, GOBEL, F. L, HERD, J. A

“…Background —The NHLBI Post Coronary Artery Bypass Graft trial (Post CABG) showed that aggressive compared with moderate lowering of low-density…”
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Effect of an aggressive lipid-lowering strategy on progression of atherosclerosis in the left main coronary artery from patients in the post coronary artery bypass graft trial by White, C W, Gobel, F L, Campeau, L, Knatterud, G L, Forman, S A, Forrester, J S, Geller, N L, Herd, J A, Hickey, A, Hoogwerf, B J, Hunninghake, D B, Rosenberg, Y, Terrin, M L

“…The Post Coronary Artery Bypass Graft Trial, designed to compare the effects of two lipid-lowering regimens and low-dose anticoagulation versus placebo on…”
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