Search Results - "FORGHANI, Farnaz"

The development of potent non-peptidic PTP-1B inhibitors by DUFRESNE, Claude, ROY, Patrick, WADDLETON, Deena, RAMACHANDRAN, Chidambaram, KENNEDY, Brian P, LIJING XU, GORDON, Robert, CHI CHUNG CHAN, LEBLANC, Yves, ZHAOYIN WANG, ASANTE-APPIAH, Ernest, CROMLISH, Wanda, BOIE, Yves, FORGHANI, Farnaz, DESMARAIS, Sylvie, QINGPING WANG, SKOREY, Kathryn

“…The SAR from our peptide libraries was exploited to design a series of potent deoxybenzoin PTP-1B inhibitors. The introduction of an ortho bromo substituent…”
Get full text

Structure based design of a series of potent and selective non peptidic PTP-1B inhibitors by LOU, Cheuk K, BAYLY, Christopher I, QINGPING WANG, SKOREY, Kathryn, WADDLETON, Deena, PAYETTE, Paul, RAMACHANDRAN, Chidambaram, KENNEDY, Brian P, SCAPIN, Giovana, GAUTHIER, Jacques Yves, CHUN SING LI, THERIEN, Michel, ASANTE-APPIAH, Ernest, CROMLISH, Wanda, BOIE, Yves, FORGHANI, Farnaz, DESMARAIS, Sylvie

“…A series of benzotriazole phenyldifluoromethylphosphonic acids were found to be potent PTP-1B inhibitors. Molecular modeling on the X-ray crystal structure of…”
Get full text

Analysis of Prostaglandin G/H Synthase-2 Inhibition Using Peroxidase-Induced Luminol Luminescence by Forghani, Farnaz, Ouellet, Marc, Keen, Sabina, Percival, M.David, Tagari, Philip

“…The inducible form of the heme-protein prostaglandin G/H synthase (PGHS-2 or COX-2) has been established as a pivotal enzyme in the cascade of events leading…”
Get full text

Characterization of functionally important sites in the bacteriophage Mu transposase protein by Ulycznyj, P I, Forghani, F, DuBow, M S

“…The 663 amino acid Mu transposase protein is absolutely required for Mu DNA transposition. Mutant proteins were constructed in vitro in order to locate regions…”
Get more information