Search Results - "FORDYCE, Colleen A"

F-actin reorganization by V-ATPase inhibition in prostate cancer by Licon-Munoz, Yamhilette, Michel, Vera, Fordyce, Colleen A, Parra, Karlett J

“…The vacuolar ATPase (V-ATPase) proton pump sustains cellular pH homeostasis, and its inhibition triggers numerous stress responses. However, the cellular…”
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Telomere DNA content and allelic imbalance demonstrate field cancerization in histologically normal tissue adjacent to breast tumors by Heaphy, Christopher M., Bisoffi, Marco, Fordyce, Colleen A., Haaland, Christina M., Hines, William C., Joste, Nancy E., Griffith, Jeffrey K.

“…Cancer arises from an accumulation of mutations that promote the selection of cells with progressively malignant phenotypes. Previous studies have shown that…”
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p38 regulates cyclooxygenase-2 in human mammary epithelial cells and is activated in premalignant tissue by GAUTHIER, Mona L, PICKERING, Curtis R, MILLER, Caroline J, FORDYCE, Colleen A, CHEW, Karen L, BERMAN, Hal K, TLSTY, Thea D

“…The immediate-early gene, cyclooxygenase-2 (COX-2), is induced in a variety of inflammatory and neoplastic processes and is believed to play an important role…”
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V-ATPase-dependent repression of androgen receptor in prostate cancer cells by Licon-Munoz, Yamhilette, Fordyce, Colleen A, Hayek, Summer Raines, Parra, Karlett J

“…Prostate Cancer (PCa) is the most commonly diagnosed cancer and the third leading cause of death for men in the United States. Suppression of androgen receptor…”
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Cell-extrinsic consequences of epithelial stress: activation of protumorigenic tissue phenotypes by Fordyce, Colleen A, Patten, Kelley T, Fessenden, Tim B, DeFilippis, RosaAnna, Hwang, E Shelley, Zhao, Jianxin, Tlsty, Thea D

“…Tumors are characterized by alterations in the epithelial and stromal compartments, which both contribute to tumor promotion. However, where, when, and how the…”
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Chemiluminescent measurement of telomere DNA content in biopsies by Fordyce, Colleen A, Heaphy, Christopher M, Griffith, Jeffrey K

“…Telomeres are nucleoprotein complexes that protect the ends of chromosomes from fusion and degradation. They are typically shorter in tumor cells than in…”
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Telomere content correlates with stage and prognosis in breast cancer by FORDYCE, Colleen A, HEAPHY, Christopher M, BISOFFI, Marco, WYACO, Jessica L, JOSTE, Nancy E, MANGALIK, Aroop, BAUMGARTNER, Kathy B, BAUMGARTNER, Richard N, HUNT, William C, GRIFFITH, Jeffrey K

“…To evaluate the hypothesis that telomere DNA content (TC) in breast tumor tissue correlates with TNM staging and prognosis. Slot blot assay was used to…”
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Association between cancer-free survival and telomere DNA content in prostate tumors by Fordyce, Colleen A, Heaphy, Christopher M, Joste, Nancy E, Smith, Anthony Y, Hunt, William C, Griffith, Jeffrey K

“…We evaluated the hypothesis that telomere DNA content (TC) in prostate tumor tissue is associated with time to prostate cancer recurrence. The cohort was…”
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Human mammary cancer progression model recapitulates methylation events associated with breast premalignancy by Dumont, Nancy, Crawford, Yongping G, Sigaroudinia, Mahvash, Nagrani, Shefali S, Wilson, Matthew B, Buehring, Gertrude C, Turashvili, Gulisa, Aparicio, Samuel, Gauthier, Mona L, Fordyce, Colleen A, McDermott, Kimberly M, Tlsty, Thea D

“…We have previously identified a rare subpopulation of variant human mammary epithelial cells (vHMEC) with repressed p16INK4A that exist in disease-free women…”
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Genetic and epigenetic changes in mammary epithelial cells may mimic early events in carcinogenesis by Tlsty, Thea D, Crawford, Yongping G, Holst, Charles R, Fordyce, Colleen A, Zhang, Jianmin, McDermott, Kimberly, Kozakiewicz, Krystyna, Gauthier, Mona L

“…Studies of human mammary epithelial cells from healthy individuals are providing novel insights into how early epigenetic and genetic events affect genomic…”
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Abstract LB-334: Signals from the microenvironment induce a malignant program accompanied by de novo epigenetic remodeling by Dumont, Nancy, Crawford, Yongping G., Reynolds, Paul A., Wilson, Matthew B., Sigaroudinia, Mahvash, Gauthier, Mona L., Fordyce, Colleen A., Tlsty, Thea D.

“…Introduction: The active acquisition of epigenetic changes is a poorly understood but important process in development, differentiation, and disease. Our work…”
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Reduced telomere DNA content is correlated with genomic instability and metastasis in invasive human breast carcinoma by GRIFFITH, J. K, BRYANT, J. E, FORDYCE, C. A, GILLILAND, F. D, JOSTE, N. E, MOYZIS, R. K

“…Telomere shortening leads to genomic instability and has been correlated with poor outcome in several types of cancer. A recently described, robust titration…”
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Genetic and epigenetic changes in mammary epithelial cells may mimic early events in carcinogenesis: Chromosomal instability and breast cancer pathogenesis by TLSTY, Thea D, CRAWFORD, Yongping G, HOLST, Charles R, FORDYCE, Colleen A, JIANMIN ZHANG, MCDERMOTT, Kimberly, KOZAKIEWICZ, Krystyna, GAUTHIER, Mona L

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Structure and function of the class C tetracycline/H+ antiporter: three independent groups of phenotypes are conferred by TetA (C) by Griffith, J K, Cuellar, D H, Fordyce, C A, Hutchings, K G, Mondragon, A A

“…The class C tetracycline/H+ antiporter, TetA(C), confers nine distinct phenotypes in Escherichia coli: resistance to tetracycline, reduced culture density at…”
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