Search Results - "FORD, Hugo E. R"

Docetaxel versus active symptom control for refractory oesophagogastric adenocarcinoma (COUGAR-02): an open-label, phase 3 randomised controlled trial by Ford, Hugo E R, Dr, Marshall, Andrea, PhD, Bridgewater, John A, PhD, Janowitz, Tobias, PhD, Coxon, Fareeda Y, MRCP, Wadsley, Jonathan, FRCR, Mansoor, Wasat, PhD, Fyfe, David, MD, Madhusudan, Srinivasan, FRCP, Middleton, Gary W, Prof, Swinson, Daniel, MD, Falk, Stephen, MD, Chau, Ian, MD, Cunningham, David, Prof, Kareclas, Paula, PhD, Cook, Natalie, PhD, Blazeby, Jane M, Prof, Dunn, Janet A, Prof

“…Summary Background Second-line chemotherapy for patients with oesophagogastric adenocarcinoma refractory to platinum and fluoropyrimidines has not shown…”
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Gefitinib Versus Vinorelbine in Chemotherapy-Naïve Elderly Patients With Advanced Non–Small-Cell Lung Cancer (INVITE): A Randomized, Phase II Study by CRINO, Lucio, CAPPUZZO, Federico, DUFFIELD, Emma L, ARMOUR, Alison A, SPEAKE, Georgina, CULLEN, Michael, ZATLOUKAL, Petr, RECK, Martin, PESEK, Milos, THOMPSON, Joyce C, FORD, Hugo E. R, HIRSCH, Fred R, VARELLA-GARCIA, Marileila, GHIORGHIU, Serban

“…This phase II, open-label, parallel-group study compared gefitinib with vinorelbine in chemotherapy-naïve elderly patients with advanced non-small-cell lung…”
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The Cost Effectiveness of Docetaxel and Active Symptom Control versus Active Symptom Control Alone for Refractory Oesophagogastric Adenocarcinoma: Economic Analysis of the COUGAR-02 Trial by Meads, David M., Marshall, Andrea, Hulme, Claire T., Dunn, Janet A., Ford, Hugo E. R.

“…Background The COUGAR-02 trial recently showed survival and quality-of-life benefits of docetaxel and active symptom control (DXL + ASC) over active symptom…”
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The role of multi-disciplinary teams in decision-making for patients with recurrent malignant disease by Strong, Sean, Blencowe, Natalie S, Fox, Tom, Reid, Colette, Crosby, Tom, Ford, Hugo ER, Blazeby, Jane M

“…Background: It is mandatory in many countries for decisions for all new patients with cancer to be made within multi-disciplinary teams (MDTs). Whether…”
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Thymidylate Synthase Expression in Advanced Colorectal Cancer Predicts for Response to Raltitrexed by FARRUGIA, David C, FORD, Hugo E. R, JACKMAN, Ann L, CUNNINGHAM, David, DANENBERG, Kathleen D, DANENBERG, Peter V, BRABENDER, Jan, MCVICAR, A. David, AHERNE, G. Wynne, HARDCASTLE, Anthea, MCCARTHY, Keith

“…Purpose: The purpose of this research was to evaluate the predictive value of expression of thymidylate synthase (TS) and other genes for response to…”
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Gefitinib for oesophageal cancer: a cog in need of a wheel? by Ford, Hugo E R

“…In early trials of EGFR inhibitors for non-small-cell lung cancer, responses were low, but subsequent work identified specific mutations in EGFR, conferring…”
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A phase II study of weekly docetaxel in patients with anthracycline pretreated metastatic breast cancer by FORD, Hugo E. R, YAP, Yoon-Sim, MILES, David W, MAKRIS, Andreas, HALL, Marcia, MILLER, Liz, HARRIES, Mark, SMITH, Ian E, JOHNSTON, Stephen R. D

“…Docetaxel has significant activity in metastatic breast cancer and weekly schedules are associated with less myelosuppression than 3-weekly schedules. We…”
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Patterns of Elevation of Plasma 2′-Deoxyuridine, a Surrogate Marker of Thymidylate Synthase (TS) Inhibition, after Administration of Two Different Schedules of 5-Fluorouracil and the Specific TS Inhibitors Raltitrexed (Tomudex) and ZD9331 by FORD, Hugo E. R, MITCHELL, Fraser, CUNNINGHAM, David, FARRUGIA, David C, HILL, Mark E, REES, Charlotte, CALVERT, A. Hilary, JUDSON, Ian R, JACKMAN, Ann L

“…5-Fluorouracil (5-FU) exerts cytotoxic effects through inhibition of thymidylate synthase (TS) and incorporation of metabolites into RNA. TS inhibition may be…”
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The Value of Routine Serum Carcino-Embryonic Antigen Measurement and Computed Tomography in the Surveillance of Patients After Adjuvant Chemotherapy for Colorectal Cancer by Chau, Ian, Allen, Mark J, Cunningham, David, Norman, Andrew R, Brown, Gina, Ford, Hugo E R, Tebbutt, Niall, Tait, Diana, Hill, Mark, Ross, Paul J, Oates, Jacqui

“…This analysis aims to evaluate routine carcino-embryonic antigen (CEA) and computed tomography (CT) of thorax, abdomen, and pelvis as part of…”
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Phase III Study of Mitomycin-C with Protracted Venous Infusion or Circadian-Timed Infusion of 5-Fluorouracil in Advanced Colorectal Carcinoma by Price, Timothy J., Ross, Paul J., Hickish, Tamas, Tait, Diana, Norman, Andy R., Ford, Hugo E.R., Middleton, Gary, Sumpter, Kate, Hill, Mark, Oates, Jacqui, Cunningham, David

“…The combination of protracted venous infusion (PVI) fluorouracil (5-FU) and mitomycin-C has previously been shown to be superior to PVI 5-FU alone in terms of…”
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Safety of raltitrexed by Ford, Hugo ER, Cunningham, David

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