Search Results - "FONSECA, C."
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Understanding alkali metal cation affinities of multi-layer guanine quadruplex DNA
Published in Physical chemistry chemical physics : PCCP (30-09-2020)“…To gain better understanding of the stabilizing interactions between metal ions and DNA quadruplexes, dispersion-corrected density functional theory (DFT-D)…”
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Impact of aging on the regenerative properties of bone marrow-, muscle-, and adipose-derived mesenchymal stem/stromal cells
Published in PloS one (26-12-2014)“…Mesenchymal stem/stromal cells (MSCs) are promising cell sources for regenerative therapies due to their multipotency and ready availability, but their…”
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Covalent Plasmodium falciparum-selective proteasome inhibitors exhibit a low propensity for generating resistance in vitro and synergize with multiple antimalarial agents
Published in PLoS pathogens (01-06-2019)“…Therapeutics with novel modes of action and a low risk of generating resistance are urgently needed to combat drug-resistant Plasmodium falciparum malaria…”
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A Narrative Review of the Antitumor Activity of Monoterpenes from Essential Oils: An Update
Published in BioMed research international (24-05-2022)“…Monoterpenes are a group of natural products that have been widely studied due to their therapeutic potential against various pathologies. These compounds are…”
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Early Moon formation inferred from hafnium–tungsten systematics
Published in Nature geoscience (01-09-2019)“…The date of the Moon-forming impact places an important constraint on Earth’s origin. Lunar age estimates range from about 30 Myr to 200 Myr after Solar System…”
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Cryptogenic stroke
Published in European journal of neurology (01-04-2015)“…In about a quarter of ischaemic strokes the cause is undetermined, because the investigation is incomplete or delayed, because there are multiple causes or…”
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Cellular mechanical properties reflect the differentiation potential of adipose-derived mesenchymal stem cells
Published in Proceedings of the National Academy of Sciences - PNAS (12-06-2012)“…The mechanical properties of adipose-derived stem cell (ASC) clones correlate with their ability to produce tissue-specific metabolites, a finding that has…”
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Evolution of the Disk in the Be Binary δ Scorpii Probed during Three Periastron Passages
Published in The Astrophysical journal (01-06-2024)“…We examine the evolution of the disk surrounding the Be star in the highly eccentric 10.8 yr binary system δ Scorpii over its three most recent periastron…”
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Hemicelluloses for fuel ethanol: A review
Published in Bioresource technology (01-07-2010)“…Hemicelluloses currently represent the largest polysaccharide fraction wasted in most cellulosic ethanol pilot and demonstration plants around the world. The…”
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Structure, densification and electrical properties of Gd3+ and Cu2+ co-doped ceria solid electrolytes for SOFC applications: Effects of Gd2O3 content
Published in Ceramics international (15-02-2018)“…Ceria-based solid electrolytes exhibit superior electrical conductivity compared to traditional yttria-stabilized zirconia ceramics. However, they require high…”
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Eigenpairs of a family of tridiagonal matrices: three decades later
Published in Acta mathematica Hungarica (01-04-2020)“…This survey paper summarizes the more important recent applications of the eigenpairs formulas for a family of tridiagonal matrices based on Losonczi’s seminal…”
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Expression of the type 3 InsP 3 receptor is a final common event in the development of hepatocellular carcinoma
Published in Gut (01-09-2019)“…Hepatocellular carcinoma (HCC) is the second leading cause of cancer death worldwide. Several types of chronic liver disease predispose to HCC, and several…”
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Association between Migraine and Cryptogenic Ischemic Stroke in Young Adults
Published in Annals of neurology (01-02-2021)“…Objective To assess the association between migraine and cryptogenic ischemic stroke (CIS) in young adults, with subgroup analyses stratified by sex and…”
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Shiga toxin-producing Escherichia coli in wild ungulates
Published in The Science of the total environment (15-02-2019)“…Shiga toxin-producing Escherichia coli (STEC) are zoonotic pathogens that live in the gastrointestinal tract of wildlife and cattle without causing disease. In…”
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How to build a proteasome
Published in Nature structural & molecular biology (01-05-2021)“…The biogenesis of eukaryotic 20S proteasomes requires the accurate assembly of 14 closely related protein subunits and occurs in a complex series of…”
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The cryo‐EM structure of the Plasmodium falciparum 20S proteasome and its use in the fight against malaria
Published in The FEBS journal (01-12-2016)“…Plasmodium falciparum is the parasite responsible for the most severe form of malaria. Its increasing resistance to existing antimalarials represents a major…”
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PET Imaging of the Neuropeptide Y System: A Systematic Review
Published in Molecules (Basel, Switzerland) (09-06-2022)“…Neuropeptide Y (NPY) is a vastly studied biological peptide with numerous physiological functions that activate the NPY receptor family (Y1, Y2, Y4 and Y5)…”
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The Impact of the COVID 19 Pandemic on Psychiatric Hospitalizations in a Portuguese Department: A Retrospective Observacional Study
Published in European psychiatry (01-08-2024)“…IntroductionThe World Health Organization declared the coronavirus outbreak a pandemic on March 11th 2020. Since then, the containment measures were leading to…”
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Environmental and Health Hazards of Chromated Copper Arsenate-Treated Wood: A Review
Published in International journal of environmental research and public health (21-05-2021)“…Copper chrome arsenate (CCA) water-borne solution used to be widely used to make timber highly resistant to pests and fungi, in particular, wood products…”
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