Search Results - "FOLLENZI, A"

Efficient gene delivery and targeted expression to hepatocytes in vivo by improved lentiviral vectors by Follenzi, A, Sabatino, G, Lombardo, A, Boccaccio, C, Naldini, L

“…Safe and efficient genetic modification of liver cells could enable new therapies for a variety of hepatic and systemic diseases. Lentiviral vectors are…”
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Cardiomyocytes Induce Endothelial Cells to Trans-Differentiate into Cardiac Muscle: Implications for Myocardium Regeneration by Condorelli, G., Borello, U., De Angelis, L., Latronico, M., Sirabella, D., Coletta, M., Galli, R., Balconi, G., Follenzi, A., Frati, G., M. G. Cusella De Angelis, Gioglio, L., Amuchastegui, S., Adorini, L., Naldini, L., Vescovi, A., Dejana, E., Cossu, G.

“…The concept of tissue-restricted differentiation of postnatal stem cells has been challenged by recent evidence showing pluripotency for hematopoietic,…”
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Generation of β cell‐specific human cytotoxic T cells by lentiviral transduction and their survival in immunodeficient human leucocyte antigen‐transgenic mice by Babad, J., Mukherjee, G., Follenzi, A., Ali, R., Roep, B. O., Shultz, L. D., Santamaria, P., Yang, O. O., Goldstein, H., Greiner, D. L., DiLorenzo, T. P.

“…Summary Several β cell antigens recognized by T cells in the non‐obese diabetic (NOD) mouse model of type 1 diabetes (T1D) are also T cell targets in the human…”
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Transplantation of endothelial cells corrects the phenotype in hemophilia A mice by KUMARAN, V., BENTEN, D., FOLLENZI, A., JOSEPH, B., SARKAR, R., GUPTA, S.

“…Background: The deficiency of factor VIII, a co‐factor in the intrinsic coagulation pathway results in hemophilia A. Although FVIII is synthesized largely in…”
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P162 TRANSCRIPTIONAL AND POST-TRANSCRIPTIONAL TARGETING OF FVIII EXPRESSION TO OVERCOME IMMUNOLOGICAL RESPONSES TO GENE THERAPY FOR HEMOPHILIA A by Merlin, S, Cannizzo, E.S, Bruscaggin, V, Feola, M, Follenzi, A

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P0021 : Altering transplanted cell engraftment and proliferation in the liver through paracrine signaling with cotransplantation of liver sinusoidal endothelial cells and hepatocytes in mice by Merlin, S, Bellofatto, K, Berishvili, E, Joseph, B, Badhe, R, Gupta, S, Follenzi, A

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Advanced cell‐based modeling of the royal disease: characterization of the mutated F9 mRNA by Martorell, L., Luce, E., Vazquez, J.L., Richaud‐Patin, Y., Jimenez‐Delgado, S., Corrales, I., Borras, N., Casacuberta‐Serra, S., Weber, A., Parra, R., Altisent, C., Follenzi, A., Dubart‐Kupperschmitt, A., Raya, A., Vidal, F., Barquinero, J.

“…Essentials The Royal disease (RD) is a form of hemophilia B predicted to be caused by a splicing mutation. We generated an iPSC‐based model of the disease…”
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Advanced cell‐based modeling of the royal disease: characterization of the mutated F9mRNA by Martorell, L., Luce, E., Vazquez, J.L., Richaud‐Patin, Y., Jimenez‐Delgado, S., Corrales, I., Borras, N., Casacuberta‐Serra, S., Weber, A., Parra, R., Altisent, C., Follenzi, A., Dubart‐Kupperschmitt, A., Raya, A., Vidal, F., Barquinero, J.

“…Essentials The Royal disease (RD) is a form of hemophilia B predicted to be caused by a splicing mutation. We generated an iPSC-based model of the disease…”
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307 ROLES OF BM CELLS IN LIVER REPOPULATION by Merlin, S, Salvatore, M, Porta, S, Zanolini, D, Follenzi, A

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P0942 : Immune reactions in steatohepatitis initiation and progression to fibrosis: Critical role of Th17 and Th22 lymphocytes by Alchera, E, Rolla, S, Imarisio, C, Bardi, V, Valente, G, Follenzi, A, Revanna Chandrashekar, B, Novelli, F, Carini, R

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Evidence for CD19B–CD8T cell interactions in blood and tissues from patients with GvHD by Deola, S, Cugno, C, Comoli, P, Guido, I, Rubert, L, Zecca, M, Zanolini, D, Follenzi, A, Langes, M, Negri, G, Tauber, M, Pusceddu, I, Cavattoni, I, Svaldi, M, Grigoleit, G U, Baumeister, E, Wang, E, Rutella, S, Marincola, F M

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1263 ADENOSINE A2a RECEPTOR STIMULATION REDUCES INFLAMMATORY Th CELLS SUBSETS IN STEATOTIC MICE LIVER AND PREVENTS PROGRESSION TO NASH by Rolla, S, Imarisio, C, Alchera, E, Follenzi, A, Albano, E, Novelli, F, Carini, R

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O40 TRANSPLANTED PRIMARY MOUSE KUPFFER CELLS ENGRAFT INDEFINITELY WITH RETENTION OF INNATE IMMUNE RESPONSES AND TISSUE REPAIR FUNCTIONS IN LIVER by Merlin, S, Bhargava, K.K, Ranaldo, G, Zanolini, D, Stevano, A, Palestro, C.J, Prat, M, Gupta, S, Follenzi, A

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Cross-talk between the proto-oncogenes Met and Ron by FOLLENZI, A, BAKOVIC, S, GUAL, P, STELLA, M, LONGATI, P, COMOGLIO, P

“…Scatter Factors control a complex genetic program known as 'invasive growth'. HGF (Scatter factor 1) and MSP (Scatter Factor 2) bind to tyrosine kinase…”
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RON is a heterodimeric tyrosine kinase receptor activated by the HGF homologue MSP by Gaudino, G., Follenzi, A., Naldini, L., Collesi, C., Santoro, M., Gallo, K.A., Godowski, P.J., Comoglio, P.M.

“…RON, a cDNA homologous to the hepatocyte growth factor (HGF) receptor gene (MET), encodes a putative tyrosine kinase. Here we show that the RON gene is…”
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361 ENGRAFTMENT AND PROLIFERATION OF TRANSPLANTED HUMAN HEPATIC STELLATE CELLS IN THE LIVER OF IMMUNODEFICIENT MICE by Benten, D, Kluwe, J, Wirth, J, Kumaran, V, Joseph, B, Volz, T, Lütgehethmann, M, Bhargava, K.K, Cheng, K, Follenzi, A, Gupta, S

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'Advanced' generation lentiviruses as efficient vectors for cardiomyocyte gene transduction in vitro and in vivo by BONCI, D, CITTADINI, A, ROSS, J. JR, NALDINI, L, PESCHLE, C, COSSU, G, CONDORELLI, G, LATRONICO, M. V. G, BORELLO, U, AYCOCK, J. K, DRUSCO, A, INNOCENZI, A, FOLLENZI, A, LAVITRANO, M, MONTI, M. G

“…Efficient gene transduction in cardiomyocytes is a task that can be accomplished only by viral vectors. Up to now, the most commonly used vectors for this…”
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Lentivectors encoding immunosuppressive proteins genetically engineer pancreatic β-cells to correct diabetes in allogeneic mice by Kojaoghlanian, T, Joseph, A, Follenzi, A, Zheng, J H, Leiser, M, Fleischer, N, Horwitz, M S, DiLorenzo, T P, Goldstein, H

“…The effectiveness of genetic engineering with lentivectors to protect transplanted cells from allogeneic rejection was examined using, as a model, type 1…”
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308 TRANSPLANTATION OF KUPFFER CELLS REPLACES RESIDENT HEPATIC MACROPHAGES CORRECTING THE BLEEDING PHENOTYPE OF HEMOPHILIC MICE by Merlin, S, Follenzi, A, Ranaldo, G, Bhargava, K.K, Palestro, C.J, Prat, M, Santambrogio, L, Gupta, S

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The proto-oncogene RON is involved in development of epithelial, bone and neuro-endocrine tissues by Gaudino, G, Avantaggiato, V, Follenzi, A, Acampora, D, Simeone, A, Comoglio, P M

“…We previously showed that the proto-oncogene RON encodes the tyrosine kinase receptor for Macrophage Stimulating Protein (MSP), originally isolated as a…”
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