Search Results - "FOLEY, A. G"

Effect of perioperative lidocaine on metastasis after sevoflurane or ketamine-xylazine anaesthesia for breast tumour resection in a murine model by Johnson, M Z, Crowley, P D, Foley, A G, Xue, C, Connolly, C, Gallagher, H C, Buggy, D J

“…Breast cancer accounts for 7% of female cancer deaths, usually attributable to metastasis. While surgery is a mainstay of treatment, perioperative…”
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Intraventricular infusions of anti–NCAM PSA impair the process of consolidation of both avoidance conditioning and spatial learning paradigms in Wistar rats by Seymour, C.M, Foley, A.G, Murphy, K.J, Regan, C.M

“…Abstract Processing of information for long-term storage requires specific patterns of activity that lead to modification of synapse structure and eventual…”
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A Synthetic Peptide Ligand of Neural Cell Adhesion Molecule (NCAM) IgI Domain Prevents NCAM Internalization and Disrupts Passive Avoidance Learning by Foley, Andrew G., Hartz, Barbara P., Gallagher, Helen C., Rønn, Lars C. B., Berezin, Vladimir, Bock, Elisabeth, Regan, Ciaran M.

“…: The neural cell adhesion molecule (NCAM) mediates cell adhesion and signal transduction through trans‐homophilic‐ and/or cis‐heterophilic‐binding mechanisms…”
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The selective 5-HT6 receptor antagonist SLV has putative cognitive- and social interaction enhancing properties in rodent models of cognitive impairment by de Bruin, N.M.W.J., van Loevezijn, A., Wicke, K.M., de Haan, M., Venhorst, J., Lange, J.H.M., de Groote, L., van der Neut, M.A.W., Prickaerts, J., Andriambeloson, E., Foley, A.G., van Drimmelen, M., van der Wetering, M., Kruse, C.G.

“…•SLV is a novel highly selective 5-HT6 antagonist.•SLV was studied in animal models for cognitive impairment and social interaction.•SLV was effective at 20…”
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Spatial Learning Activates Neural Cell Adhesion Molecule Polysialylation in a Corticohippocampal Pathway Within the Medial Temporal Lobe by O'Connell, Alan W., Fox, Gerard B., Barry, Thomas, Murphy, Keith J., Fichera, Giacomo, Foley, Andrew G., Kelly, John, Regan, Ciaran M.

“…: Transient and time‐dependent modulations of neural cell adhesion molecule (NCAM) polysialylation in the dentate gyrus of the rodent hippocampus are a feature…”
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Syntheses of benzoquinolizidine and benzoindolizidine derivatives as anti-amnesic agents by SHIKAI ZHAO, TOTLEBEN, M. J, MIZSAK, S. A, SZMUSZKOVICZ, J, FREEMAN, J. P, BACON, C. L, FOX, G. B, O'DRISCOLL, E, FOLEY, A. G, KELLY, J, FARRELL, U, REGAN, C

“…Tacrine, one of the drugs available for Alzheimer's disease based on the cholinergic approach, suffers from considerable toxicity. Many analogues of tacrine…”
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Syntheses of 1,2-diamino and 1,2-aminoalcohol derivatives in the piperidine and pyrrolidine series as anti-amnesic agents by SHIKAI ZHAO, FREEMAN, J. P, SZMUSZKOVICZ, J, BACON, C. L, FOX, G. B, O'DRISCOLL, E, FOLEY, A. G, KELLY, J, FARRELL, U, REGAN, C, MIZSAK, S. A

“…Tacrine, one of the drugs available for Alzheimer's disease based on the cholinergic approach, suffers from considerable toxicity. Many analogues of tacrine…”
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Consolidation of memory for odour-reward association requires transient polysialylation of the neural cell adhesion molecule in the rat hippocampal dentate gyrus by Foley, Andrew G., Hedigan, Kate, Roullet, Pascal, Moricard, Yves, Murphy, Keith J., Sara, Susan J., Regan, Ciaran M.

“…Cell adhesion molecule function is involved in hippocampal synaptic plasticity and is associated with memory consolidation. At the infragranular zone of the…”
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Distribution of polysialylated neural cell adhesion molecule in rat septal nuclei and septohippocampal pathway: Transient increase of polysialylated interneurons in the subtriangular septal zone during memory consolidation by Foley, Andrew G., Rønn, Lars C.B., Murphy, Keith J., Regan, Ciaran M.

“…During memory consolidation neuroplastic events in the mediotemporal corticohippocampal pathway are accompanied by transient increases in the frequency of…”
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Pentyl‐4‐yn‐valproic acid enhances both spatial and avoidance learning and attenuates age‐related NCAM‐mediated neuroplastic decline within the rat medial temporal lobe by Murphy, Keith J., Fox, Gerard B., Foley, Andrew G., Gallagher, Helen C., O'Connell, Alan, Griffin, Anne‐Marie, Nau, Heinz, Regan, Ciaran M.

“…2‐N‐Pentyl‐4‐pentynoic acid [pentyl‐4‐yn‐valproic acid (VPA)] is an analogue of valproic acid that induces neuritogenesis and increases neural cell adhesion…”
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Protein kinase C delta regulates neural cell adhesion molecule polysialylation state in the rat brain by Gallagher, Helen C., Murphy, Keith J., Foley, Andrew G., Regan, Ciaran M.

“…Polysialylation of neural cell adhesion molecule (NCAM PSA) modulates cell–cell homophilic binding and signalling during brain development and the remodelling…”
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Pentyl-4-yn-valproic acid reverses age-associated memory impairment in the Wistar rat by Foley, Andrew G, Gallagher, Helen C, Murphy, Keith J, Regan, Ciaran M

“…Pentyl-4-yn-valproic acid (VPA), a cognition-enhancing agent whose mode of action has been attributed to cell adhesion molecule-mediated neuritogenesis, has…”
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The detection of selective phase corrosion in cast nickel aluminium bronze by acoustic emission techniques by CULPAN, E.A, FOLEY, A.G

“…Cast Ni Al bronze (NAB) can suffer severe selective phase corrosion in sea water by a dealuminification process similar to dezincification in brasses. During…”
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The 5-HT6 receptor antagonist SB-271046 reverses scopolamine-disrupted consolidation of a passive avoidance task and ameliorates spatial task deficits in aged rats by FOLEY, Andrew G, MURPHY, Keith J, HIRST, Warren D, GALLAGHER, Helen C, HAGAN, Jim J, UPTON, Neil, WALSH, Frank S, REGAN, Ciaran M

“…The highly potent and selective 5-HT(6) receptor antagonist SB-271046 [5-chloro-N-(4-methoxy-3-piperazin-1-yl-phenyl)-3-methyl-2-benzothiophenesulfonamide] has…”
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Differential enantioselective effects of pentyl‐4‐yn‐valproate on spatial learning in the rat, and neurite outgrowth and cyclin D3 expression in vitro by D. O'Loinsigh, Eamon, Gherardini, Lisa M., Gallagher, Helen C., Foley, Andrew G., Murphy, Keith J., Regan, Ciaran M.

“…Previously, we demonstrated the racemic form of the valproate (VPA) analogue, 2‐n‐pentyl‐4‐pentynoic acid ([±]pentyl‐4‐yn‐VPA), to be neuritogenic in vitro and…”
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Consolidation of memory for odour-reward association requires transient polysialyation of the neural cell adhesion molecule in the rat hippocampal dentate gyrus by G. Foley, A., Hedigan, K., Roullet, P., Moricard, Y., J. Murphy, K., J. Sara, S., M. Regan, C.

“…Cell adhesion molecule function is involved in hippocampal synaptic plasticity and is associated with memory consolidation. At the infragranular zone of the…”
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Chronic Exposure of Rats to Cognition Enhancing Drugs Produces a Neuroplastic Response Identical to that Obtained by Complex Environment Rearing by MURPHY, Keith J, FOLEY, Andrew G, O'CONNELL, Alan W, REGAN, Ciaran M

“…Recent data suggest that Alzheimer's patients who discontinue treatment with cholinesterase inhibitors have a significantly delayed cognitive decline as…”
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Complex-environment rearing prevents prenatal hypoxia-induced deficits in hippocampal cellular mechanisms necessary for memory consolidation in the adult Wistar rat by Foley, Andrew G, Murphy, Keith J, Regan, Ciaran M

“…Hypoxic episodes in utero can result in enduring and debilitating neurological sequelae that include nonprogressive motor disorders and/or significant learning…”
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