Search Results - "FLYNN, Robert W. V"

Increased mortality and morbidity in mild primary hyperparathyroid patients. The Parathyroid Epidemiology and Audit Research Study (PEARS) by Yu, Ning, Donnan, Peter T., Flynn, Robert W. V., Murphy, Michael J., Smith, David, Rudman, Andrew, Leese, Graham P.

“…Summary Objective  To describe mortality and disease‐specific morbidities in patients with mild primary hyperparathyroidism (PHPT). Design  Retrospective…”
Get full text

The effect of changes to GOLD severity stage on long term morbidity and mortality in COPD by Flynn, Robert W V, MacDonald, Thomas M, Chalmers, James D, Schembri, Stuart

“…The Global Initiative for Chronic Obstructive Lung Disease (GOLD) severity stage classifies Chronic Obstructive Pulmonary Disease (COPD) into groups based on…”
Get full text

Evaluating Diuretics in Normal Care (EVIDENCE): protocol of a cluster randomised controlled equivalence trial of prescribing policy to compare the effectiveness of thiazide-type diuretics in hypertension by Rogers, Amy, Flynn, Angela, Mackenzie, Isla S, McConnachie, Lewis, Barr, Rebecca, Flynn, Robert W V, Morant, Steve, MacDonald, Thomas M, Doney, Alexander

“…Healthcare systems must use treatments that are effective and safe. Regulators licensed many currently used older medications before introducing the stringent…”
Get full text

Correction to: The Treatment In Morning versus Evening (TIME) study: analysis of recruitment, follow-up and retention rates post-recruitment by Rorie, David A, Flynn, Robert W. V, Mackenzie, Isla S, MacDonald, Thomas M, Rogers, Amy

Get full text

The Treatment In Morning versus Evening (TIME) study: analysis of recruitment, follow-up and retention rates post-recruitment by Rorie, David A, Flynn, Robert W V, Mackenzie, Isla S, MacDonald, Thomas M, Rogers, Amy

“…The use of information technology (IT) is now the preferred method of capturing and storing clinical research data. The Treatment In Morning versus Evening…”
Get full text

Does the provision of a DVD-based audio-visual presentation improve recruitment in a clinical trial? A randomised trial of DVD trial invitations by Rogers, Amy, Flynn, Robert W V, Mackenzie, Isla S, MacDonald, Thomas M

“…Recruitment to clinical trials can be challenging. Methods that improve the efficiency of trial recruitment are needed to increase successful study…”
Get full text

Prescribing Antiplatelet Medicine and Subsequent Events After Intracerebral Hemorrhage by FLYNN, Robert W. V, MACDONALD, Thomas M, MURRAY, Gordon D, MACWALTER, Ronald S, DONEY, Alexander S. F

“…Antiplatelet medicines are commonly perceived as contraindicated after intracerebral hemorrhage (ICH). Many ICH patients have or will have indications for…”
Get full text

Drugs Dispensed in Primary Care During Pregnancy: A Record-Linkage Analysis in Tayside, Scotland by Irvine, Linda, Flynn, Robert W.V., Libby, Gillian, Crombie, Iain K., Evans, Josie M.M.

“…Background: For many regularly used drugs, evidence for safe use in pregnancy has not been established. Despite this, international studies have identified…”
Get full text

Evaluating Diuretics in Normal Care (EVIDENCE): a feasibility report of a pilot cluster randomised trial of prescribing policy in primary care to compare the effectiveness of thiazide-type diuretics in hypertension by Flynn, Angela, Rogers, Amy, McConnachie, Lewis, Barr, Rebecca, Flynn, Robert W V, Mackenzie, Isla S, MacDonald, Thomas M, Doney, Alexander S F

“…Obtaining evidence on comparative effectiveness and safety of widely prescribed drugs in a timely and cost-effective way is a major challenge for healthcare…”
Get full text

Persistence, adherence and outcomes with antiplatelet regimens following cerebral infarction in the Tayside Stroke Cohort by Flynn, Robert W V, MacDonald, Thomas M, Murray, Gordon D, MacWalter, Ronald S, Doney, Alexander S F

“…Co-prescribed aspirin and dipyridamole are more effective than aspirin alone following cerebral infarction; however, patients may struggle with this more…”
Get more information

The effect of indapamide vs. bendroflumethiazide for primary hypertension: a systematic review by Macfarlane, Tatiana V., Pigazzani, Filippo, Flynn, Robert W.V., MacDonald, Thomas M.

“…The aims of the current review were to compare the efficacy of monotherapy with bendroflumethiazide vs. indapamide on mortality, cardiovascular outcomes, blood…”
Get full text

Electronic case report forms and electronic data capture within clinical trials and pharmacoepidemiology by Rorie, David A., Flynn, Robert W. V., Grieve, Kerr, Doney, Alexander, Mackenzie, Isla, MacDonald, Thomas M., Rogers, Amy

“…Aims Researchers in clinical and pharmacoepidemiology fields have adopted information technology (IT) and electronic data capture, but these remain underused…”
Get full text

Factors influencing home blood pressure monitor ownership in a large clinical trial by Anbarasan, Thineskrishna, Rogers, Amy, Rorie, David A., Grieve, J. W. Kerr, Flynn, Robert W. V., MacDonald, Thomas M., Mackenzie, Isla S.

“…Home blood pressure monitor (HBPM) ownership prevalence and the factors that influence it are unclear. This study aimed to investigate factors associated with…”
Get full text

Systematic review of observational research studying the long-term use of antithrombotic medicines following intracerebral hemorrhage by Flynn, Robert W V, MacDonald, Thomas M, Murray, Gordon D, Doney, Alexander S F

“…Patients with intracerebral hemorrhage frequently have indications for antithrombotic therapy. This represents a therapeutic dilemma as intracerebral…”
Get more information

Cardiovascular Safety of Prucalopride in Patients with Chronic Constipation: A Multinational Population-Based Cohort Study by Gilsenan, Alicia, Fortuny, Joan, Cainzos-Achirica, Miguel, Cantero, Oscar F., Flynn, Robert W. V., Garcia-Rodriguez, Luis, Harding, Abenah, Kollhorst, Bianca, Karlsson, Pär, Linnér, Love, MacDonald, Thomas M., Odsbu, Ingvild, Plana, Estel, Ruigómez, Ana, Schink, Tania, Ziemiecki, Ryan, Andrews, Elizabeth B.

“…Introduction The serotonin 5-HT 4 receptor agonist prucalopride is approved in the European Union for the treatment of chronic constipation. This offered the…”
Get full text

Identification and Validation of Major Cardiovascular Events in the United Kingdom Data Sources Included in a Multi-database Post-authorization Safety Study of Prucalopride by Ruigómez, Ana, Plana, Estel, Gilsenan, Alicia, Fortuny, Joan, Cainzos-Achirica, Miguel, Flynn, Robert W. V., MacDonald, Thomas M., Garcia-Rodriguez, Luis, Ziemiecki, Ryan, Andrews, Elizabeth B.

“…Introduction A multinational post-authorization safety study assessed cardiovascular safety in initiators of prucalopride for chronic constipation compared…”
Get full text

Renal impairment after high-dose flucloxacillin and single-dose gentamicin prophylaxis in patients undergoing elective hip and knee replacement by Challagundla, Sudhakar Rao, Knox, David, Hawkins, Amanda, Hamilton, David, W V Flynn, Robert, Robertson, Sue, Isles, Chris

“…Following advice from the Scottish Antimicrobial Prescribing Group, we switched our antibiotic prophylaxis for elective hip and knee replacement surgery from…”
Get full text

Impact of EMA regulatory label changes on systemic diclofenac initiation, discontinuation, and switching to other pain medicines in Scotland, England, Denmark, and The Netherlands by Morales, Daniel R., Morant, Steve V., MacDonald, Thomas M., Mackenzie, Isla S., Doney, Alexander S. F., Mitchell, Lyn, Bennie, Marion, Robertson, Chris, Hallas, Jesper, Pottegard, Anton, Ernst, Martin Thomsen, Wei, Li, Nicholson, Lizzie, Morris, Carole, Herings, Ron M. C., Overbeek, Jetty A., Smits, Elisabeth, Flynn, Robert W. V.

“…Purpose In June 2013 a European Medicines Agency referral procedure concluded that diclofenac was associated with an elevated risk of acute cardiovascular…”
Get full text

Effect of timed dosing of usual antihypertensives according to patient chronotype on cardiovascular outcomes: the Chronotype sub-study cohort of the Treatment in Morning versus Evening (TIME) study by Pigazzani, Filippo, Dyar, Kenneth A., Morant, Steve V., Vetter, Céline, Rogers, Amy, Flynn, Robert W.V., Rorie, David A., Mackenzie, Isla S., Cappuccio, Francesco P., Manfredini, Roberto, MacDonald, Thomas M.

“…Timing drug administration to endogenous circadian rhythms may enhance treatment efficacy. In the Chronotype sub-study of the Treatment in Morning versus…”
Get full text

Study Design and Cohort Comparability in a Study of Major Cardiovascular Events in New Users of Prucalopride Versus Polyethylene Glycol 3350 by Fortuny, Joan, Gilsenan, Alicia, Cainzos-Achirica, Miguel, Cantero, Oscar F., Flynn, Robert W. V., Garcia-Rodriguez, Luis, Kollhorst, Bianca, Karlsson, Pär, Linnér, Love, MacDonald, Thomas M., Plana, Estel, Ruigómez, Ana, Schink, Tania, Ziemiecki, Ryan, Andrews, Elizabeth B.

“…Introduction Given prior safety experience with other 5-HT 4 agonists for chronic constipation, an observational, population-based cohort study in five data…”
Get full text