Search Results - "FLOTHO, C"

The DNA methyltransferase inhibitors azacitidine, decitabine and zebularine exert differential effects on cancer gene expression in acute myeloid leukemia cells by Flotho, C, Claus, R, Batz, C, Schneider, M, Sandrock, I, Ihde, S, Plass, C, Niemeyer, C M, Lübbert, M

“…The three DNA methyltransferase (DNMT)-inhibiting cytosine nucleoside analogues, azacitidine, decitabine and zebularine, which are currently studied as…”
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Mutational landscape in children with myelodysplastic syndromes is distinct from adults: specific somatic drivers and novel germline variants by Pastor, V, Hirabayashi, S, Karow, A, Wehrle, J, Kozyra, E J, Nienhold, R, Ruzaike, G, Lebrecht, D, Yoshimi, A, Niewisch, M, Ripperger, T, Göhring, G, Baumann, I, Schwarz, S, Strahm, B, Flotho, C, Skoda, R C, Niemeyer, C M, Wlodarski, M W

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21 Juvenile myelomonocytic leukemia by Flotho, C

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New Development in Childhood MDS by Niemeyer, C, Strahm, B, Pastor, V, Flotho, C, Yoshimi, A, Wlodarski, M

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OVERVIEW OF PEDIATRIC MDS AND JMML by Flotho, C.

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Genome-wide single-nucleotide polymorphism analysis in juvenile myelomonocytic leukemia identifies uniparental disomy surrounding the NF1 locus in cases associated with neurofibromatosis but not in cases with mutant RAS or PTPN11 by FLOTHO, C, STEINEMANN, D, MULLIGHAN, C. G, NEALE, G, MAYER, K, KRATZ, C. P, SCHLEGELBERGER, B, DOWNING, J. R, NIEMEYER, C. M

“…Juvenile myelomonocytic leukemia (JMML) is a malignant hematopoietic disorder whose proliferative component is a result of RAS pathway deregulation caused by…”
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Successful double umbilical cord blood transplantation for relapsed juvenile myelomonocytic leukemia by Flotho, C, Vraetz, T, Lang, P, Niemeyer, C M, Strahm, B

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P359: IMPROVED OVERALL SURVIVAL AND MRD CLEARANCE WITH BLINATUMOMAB VS CHEMOTHERAPY AS PRE‐TRANSPLANT CONSOLIDATION IN PEDIATRIC HIGH‐RISK FIRST‐RELAPSE B‐CELL PRECURSOR ACUTE LYMPHOBLASTIC LEUKEMIA (B‐ALL) by Locatelli, F., Zugmaier, G., Rizzari, C., Morris, J., Gruhn, B., Klingebiel, T., Parasole, R., Linderkamp, C., Flotho, C., Petit, A., Micalizzi, C., Zeng, Y., Desai, R., Kormany, W., Eckert, C., Möricke, A., Sartor, M., Hrusak, O., Peters, C., Saha, V., Vinti, L., Stackelberg, A.

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Genome-Wide DNA Methylation Profiling Reveals Distinct Molecular Subgroups of Juvenile Myelomonocytic Leukemia with Clinical Significance by Lipka, D, Witte, T, Toth, R, Yang, J, Baude, A, Wiesenfarth, M, Brocks, D, Mücke, O, Nöllke, P, Assenov, Y, Schlesner, M, Niemeyer, C, Plass, C, Flotho, C

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Mutation analysis of Son of Sevenless in juvenile myelomonocytic leukemia by Kratz, C P, Niemeyer, C M, Thomas, C, Bauhuber, S, Matejas, V, Bergsträsser, E, Flotho, C, Flores, N J, Haas, O, Hasle, H, van den Heuvel-Eibrink, M M, Kucherlapati, R S, Lang, P, Roberts, A E, Starý, J, Strahm, B, Swanson, K D, Trebo, M, Zecca, M, Neel, B, Locatelli, F, Loh, M L, Zenker, M

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RAS mutations and clonality analysis in children with juvenile myelomonocytic leukemia (JMML) by FLOTHO, C, VALCAMONICA, S, MACH-PASCUAL, S, SCHMAHL, G, CORRAL, L, RITTERBACH, J, HASLE, H, ARICO, M, BIONDI, A, NIEMEYER, C. M

“…Juvenile myelomonocytic leukemia (JMML) is a malignant hematopoietic disorder of early childhood with excessive proliferation of the myeloid and monocytic…”
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Clonal duplication of a germline PTPN11 mutation due to acquired uniparental disomy in acute lymphoblastic leukemia blasts from a patient with noonan syndrome by KAROW, A, STEINEMANN, D, KRATZ, C. P, GÖHRING, G, HASLE, H, GREINER, J, HARILA-SAARI, A, FLOTHO, C, ZENKER, M, SCHLEGELBERGER, B, NIEMEYER, C. M

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232 Relevance of WT1 expression, mutations and single nucleotide polymorphisms in juvenile myelomonocytic leukemia by de Vries, A, Zwaan, M, Hollink, I, Willasch, A, Alders, M, de Haas, V, Dworzak, M, Hasle, H, Locatelli, F, Zecca, M, de Moerloose, B, Stary, J, Niemeyer, C, Flotho, C, Bader, P, Pieters, R, van den Heuvel-Eibrink, M

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190 - New Development in Childhood MDS by Niemeyer, C., Strahm, B., Pastor, V., Flotho, C., Yoshimi, A., Wlodarski, M.

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Topic: AS06-Prognosis/AS06b-Predictive factors of response to treatment by Yoshimi, A., Vinci, L., Flotho, C., Noellke, P., Erlacher, M., Lebrecht, D., Masetti, R., De Haas, V., De Moerloose, B., Dworzak, M., Hasle, H., Schmugge, M., Stary, J., Turkiewicz, D., Ussowicz, M., Catala, A., Buechner, J., Jahnukainen, K., Kállay, K., Fabri, O., Smith, O., Göhring, G., Locatelli, F., Strahm, B., Niemeyer, C.

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O27 - Topic: AS06-Prognosis/AS06b-Predictive factors of response to treatment: OUTCOMES OF RELAPSED JUVENILE MYELOMONOCYTIC LEUKEMIA: THE ROLE OF SECOND HEMATOPOIETIC STEM CELL TRANSPLANTATION by Yoshimi, A., Vinci, L., Flotho, C., Noellke, P., Erlacher, M., Lebrecht, D., Masetti, R., De Haas, V., De Moerloose, B., Dworzak, M., Hasle, H., Schmugge, M., Stary, J., Turkiewicz, D., Ussowicz, M., Catala, A., Buechner, J., Jahnukainen, K., Kállay, K., Fabri, O., Smith, O., Göhring, G., Locatelli, F., Strahm, B., Niemeyer, C.

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Topic: AS04-MDS Biology and Pathogenesis/AS04b-Clonal diversity & evolution by Sahoo, S., Pastor, V., Goodings, C., Noellke, P., Dworzak, M., Stary, J., Locatelli, F., Masetti, R., Schmugge, M., De Moerloose, B., Catala, A., Kállay, K., Turkiewicz, D., Hasle, H., Buechner, J., Jahnukainen, K., Ussowicz, M., Polychronopoulou, S., Smith, O., Fabri, O., Barzilai, S., De Haas, V., Baumann, I., Schwarz-Furlan, S., Göhring, G., Yoshimi, A., Flotho, C., Strahm, B., Erlacher, M., Niemeyer, C., Wlodarski, M.

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O05 - Topic: AS04-MDS Biology and Pathogenesis/AS04b-Clonal diversity & evolution: SOMATIC GENETIC RESCUE IN SAMD9/SAMD9L MDS PREDISPOSITION SYNDROMES by Sahoo, S., Pastor, V., Goodings, C., Noellke, P., Dworzak, M., Stary, J., Locatelli, F., Masetti, R., Schmugge, M., De Moerloose, B., Catala, A., Kállay, K., Turkiewicz, D., Hasle, H., Buechner, J., Jahnukainen, K., Ussowicz, M., Polychronopoulou, S., Smith, O., Fabri, O., Barzilai, S., De Haas, V., Baumann, I., Schwarz-Furlan, S., Göhring, G., Yoshimi, A., Flotho, C., Strahm, B., Erlacher, M., Niemeyer, C., Wlodarski, M.

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Long-term serial xenotransplantation of juvenile myelomonocytic leukemia recapitulates human disease in Rag2-/- c-/- mice by Krombholz, C. F., Aumann, K., Kollek, M., Bertele, D., Fluhr, S., Kunze, M., Niemeyer, C. M., Flotho, C., Erlacher, M.

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Criteria for evaluating response and outcome in clinical trials for children with juvenile myelomonocytic leukemia by Niemeyer, Charlotte M, Loh, Mignon L, Cseh, Annamaria, Cooper, Todd, Dvorak, Christopher C, Chan, Rebecca, Xicoy, Blanca, Germing, Ulrich, Kojima, Seiji, Manabe, Atsushi, Dworzak, Michael, De Moerloose, Barbara, Starý, Jan, Smith, Owen P, Masetti, Riccardo, Catala, Albert, Bergstraesser, Eva, Ussowicz, Marek, Fabri, Oskana, Baruchel, André, Cavé, Hélène, Zwaan, Michel, Locatelli, Franco, Hasle, Henrik, van den Heuvel-Eibrink, Marry M, Flotho, Christian, Yoshimi, Ayami

“…Juvenile myelomonocytic leukemia is a rare myeloproliferative disease in young children. While hematopoietic stem cell transplantation remains the only…”
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