Search Results - "FLORESCO, Stan B"

The Nucleus Accumbens: An Interface Between Cognition, Emotion, and Action by Floresco, Stan B

“…Nearly 40 years of research on the function of the nucleus accumbens (NAc) has provided a wealth of information on its contributions to behavior but has also…”
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Prefrontal dopamine and behavioral flexibility: shifting from an "inverted-U" toward a family of functions by Floresco, Stan B

“…Studies on prefrontal cortex (PFC) dopamine (DA) function have revealed its essential role in mediating a variety of cognitive and executive functions. A…”
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Prefrontal-hippocampal interactions supporting the extinction of emotional memories: the retrieval stopping model by Anderson, Michael C, Floresco, Stan B

“…Neuroimaging has revealed robust interactions between the prefrontal cortex and the hippocampus when people stop memory retrieval. Efforts to stop retrieval…”
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Deciphering Decision Making: Variation in Animal Models of Effort- and Uncertainty-Based Choice Reveals Distinct Neural Circuitries Underlying Core Cognitive Processes by Winstanley, Catharine A, Floresco, Stan B

“…Maladaptive decision-making is increasingly recognized to play a significant role in numerous psychiatric disorders, such that therapeutics capable of…”
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Multifaceted Contributions by Different Regions of the Orbitofrontal and Medial Prefrontal Cortex to Probabilistic Reversal Learning by Dalton, Gemma L, Wang, Nena Y, Phillips, Anthony G, Floresco, Stan B

“…Different subregions of the prefrontal cortex (PFC) contribute to the ability to respond flexibly to changes in reward contingencies, with the medial versus…”
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Prefrontal Dopamine D1 and D2 Receptors Regulate Dissociable Aspects of Decision Making via Distinct Ventral Striatal and Amygdalar Circuits by Jenni, Nicole L, Larkin, Joshua D, Floresco, Stan B

“…Mesocortical dopamine (DA) regulates a variety of cognitive functions via actions on D1 and/or D2 receptors. For example, risk/reward decision making is…”
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Overriding phasic dopamine signals redirects action selection during risk/reward decision making by Stopper, Colin M, Tse, Maric T L, Montes, David R, Wiedman, Candice R, Floresco, Stan B

“…Phasic increases and decreases in dopamine (DA) transmission encode reward prediction errors thought to facilitate reward-related learning, yet how these…”
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Abrupt Transitions between Prefrontal Neural Ensemble States Accompany Behavioral Transitions during Rule Learning by Durstewitz, Daniel, Vittoz, Nicole M., Floresco, Stan B., Seamans, Jeremy K.

“…One of the most intriguing aspects of adaptive behavior involves the inference of regularities and rules in ever-changing environments. Rules are often deduced…”
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Differential Effects on Effort Discounting Induced by Inactivations of the Nucleus Accumbens Core or Shell by Ghods-Sharifi, Sarvin, Floresco, Stan B

“…The authors investigated the contribution of the nucleus accumbens (NAc) core and shell to effort-based decision making using a discounting procedure…”
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Preferential involvement by nucleus accumbens shell in mediating probabilistic learning and reversal shifts by Dalton, Gemma L, Phillips, Anthony G, Floresco, Stan B

“…Different subregions of nucleus accumbens (NAc) have been implicated in reward seeking, promoting flexible approach responses, suppressing nonrewarded actions,…”
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Prefrontal Cortical Gamma-Aminobutyric Acid Transmission and Cognitive Function: Drawing Links to Schizophrenia from Preclinical Research by Tse, Maric T, Piantadosi, Patrick T, Floresco, Stan B

“…Abstract Cognitive dysfunction in schizophrenia is one of the most pervasive and debilitating aspects of the disorder. Among the numerous neural abnormalities…”
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Dopaminergic and Glutamatergic Regulation of Effort- and Delay-Based Decision Making by FLORESCO, Stan B, TSE, Maric T. L, GHODS-SHARIFI, Sarvin

“…Cost/benefit decisions regarding the relative effort or delay costs associated with a particular response are mediated by distributed dopaminergic and…”
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Dopaminergic Modulation of Risk-Based Decision Making by ONGE, Jennifer R. St, FLORESCO, Stan B

“…Psychopharmacological studies have implicated the mesolimbic dopamine (DA) system in the mediation of cost/benefit evaluations about delay or effort-related…”
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Regulation of firing of dopaminergic neurons and control of goal-directed behaviors by Grace, Anthony A, Floresco, Stan B, Goto, Yukiori, Lodge, Daniel J

“…There are several brain regions that have been implicated in the control of motivated behavior and whose disruption leads to the pathophysiology observed in…”
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Dopamine Neurons, Input Integration, and Reward Prediction Errors: E Pluribus Unum by Floresco, Stan B.

“…Dopamine neurons encode errors in reward prediction, yet understanding how they integrate information from different subcortical inputs to generate these…”
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Orexin A/Hypocretin-1 Selectively Promotes Motivation for Positive Reinforcers by Borgland, Stephanie L, Chang, Shao-Ju, Bowers, M. Scott, Thompson, Jennifer L, Vittoz, Nicole, Floresco, Stan B, Chou, Jonathan, Chen, Billy T, Bonci, Antonello

“…Orexin A/hypocretin-1 (oxA/hcrt-1) is known to be a modulator of dopamine-dependent neuronal activity and behaviors. However, the role of this system in…”
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Dopaminergic Regulation of Inhibitory and Excitatory Transmission in the Basolateral Amygdala-Prefrontal Cortical Pathway by Floresco, Stan B, Tse, Maric T

“…Projections from the basolateral amygdala (BLA) and dopamine (DA) input from the ventral tegmental area (VTA) converge in the medial prefrontal cortex (mPFC),…”
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Contributions of basolateral amygdala and nucleus accumbens subregions to mediating motivational conflict during punished reward-seeking by Piantadosi, Patrick T., Yeates, Dylan C.M., Wilkins, Mathew, Floresco, Stan B.

“…•The basolateral amygdala and accumbens shell suppress punished reward seeking.•These regions also promote reward seeking in aversive contexts.•The accumbens…”
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Dynamic fluctuations in dopamine efflux in the prefrontal cortex and nucleus accumbens during risk-based decision making by St Onge, Jennifer R, Ahn, Soyon, Phillips, Anthony G, Floresco, Stan B

“…Mesocorticolimbic dopamine (DA) has been implicated in cost/benefit decision making about risks and rewards. The prefrontal cortex (PFC) and nucleus accumbens…”
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Acute stress differentially alters reward-related decision making and inhibitory control under threat of punishment by Laino Chiavegatti, Giulio, Floresco, Stan B.

“…Acute stress has various effects on cognition, executive function and certain forms of cost/benefit decision making. Recent studies in rodents indicate that…”
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