Search Results - "FLORES, ALEJANDRA"

HRS-4642: The next piece of the puzzle to keep KRAS in check by Flores-Gómez, Alejandra A, Drosten, Matthias

“…KRAS is the most frequent KRAS mutation in human cancer. In this issue, Zhou et al. describe a novel KRAS inhibitor, HRS-4642, that shows potent and selective…”
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Cognitive modeling for understanding interactions between people and decision support tools in complex and uncertain environments: A study protocol by Molina, Isaac, Molina-Perez, Edmundo, Sobrino, Fernanda, Tellez-Rojas, Mario, Serra-Barragan, Luis, Castellón-Flores, Alejandra Mitzi, Orozco, Yessica, de Unanue, Adolfo, Rojas-Iturria, Fatima

“…Background Recent advances in Computational Intelligence Tools and the escalating need for decision-making in the face of complex and uncertain phenomena like…”
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Sentence-final completion norms for 2925 Mexican Spanish sentence contexts by Angulo-Chavira, Armando Quetzalcóatl, Castellón-Flores, Alejandra Mitzi, Ciria, Alejandra, Arias-Trejo, Natalia

“…Sentence-final completion tasks serve as valuable tools in studying language processing and the associated predictive mechanisms. There are several established…”
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Impact of pelvic radiation therapy in patients with early neuroendocrine cervical carcinoma and no residual disease in the radical hysterectomy specimen: a NeCTuR study by Khurana, Nilsha, Frumovitz, Michael, Flores Legarreta, Alejandra, Ramalingam, Preetha, Jhingran, Anuja, Bhosale, Priya, Saab, Reem, Gonzales, Naomi R R, Chisholm, Gary B, Salvo, Gloria

“…The impact of adjuvant pelvic radiation therapy on the rate and location of recurrences was evaluated in patients with early-stage (IA1-IB2) neuroendocrine…”
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Word prediction using closely and moderately related verbs in Down syndrome by Angulo-Chavira, Armando Q., Castellón-Flores, Alejandra M., Barrón-Martínez, Julia B., Arias-Trejo, Natalia

“…People with Down syndrome (DS) have several difficulties in language learning, and one of the areas most affected is language production. Theoretical…”
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Juvenile stress causes reduced locomotor behavior and dendritic spine density in the prefrontal cortex and basolateral amygdala in Sprague–Dawley rats by Pinzón‐Parra, Cesar, Vidal‐Jiménez, Blanca, Camacho‐Abrego, Israel, Flores‐Gómez, Alejandra A., Rodríguez‐Moreno, Antonio, Flores, Gonzalo

“…Little has been investigated about the effects of stress on synaptic communication at prepubertal age, a stage considered as juvenile. This period of…”
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Alternative splicing of the SUMO1/2/3 transcripts affects cellular SUMOylation and produces functionally distinct SUMO protein isoforms by Acuña, Myriah L., García-Morin, Andrea, Orozco-Sepúlveda, Rebeca, Ontiveros, Carlos, Flores, Alejandra, Diaz, Arely V., Gutiérrez-Zubiate, Isabel, Patil, Abhijeet R., Alvarado, Luis A., Roy, Sourav, Russell, William K., Rosas-Acosta, Germán

“…Substantial increases in the conjugation of the main human SUMO paralogs, SUMO1, SUMO2, and SUMO3, are observed upon exposure to different cellular stressors,…”
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Serial cytoreductive surgery and survival outcomes in recurrent adult-type ovarian granulosa cell tumors by How, Jeffrey A., Legarreta, Alejandra Flores, Handley, Katelyn F., Fellman, Bryan, Foster, Katherine I., Glassman, Deanna, Vuttaradhi, Veena K., Brodsky, Allison L., Lawson, Barrett, Frumovitz, Michael, Westin, Shannon N., Ramondetta, Lois M., Gershenson, David M., Sood, Anil K., Hillman, R. Tyler

“…Few studies have evaluated the role of cytoreductive surgery in patients with recurrent adult granulosa cell tumors of the ovary. Despite a multitude of…”
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Consequences of diabetes mellitus on neuronal connectivity in limbic regions by Flores‐Gómez, Alejandra Aketzalli, Jesús Gomez‐Villalobos, Ma, Flores, Gonzalo

“…Diabetes mellitus (DM) is characterized by high levels of blood glucose. In recent years, its prevalence has increased, which was 422 million in the world in…”
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Clinical significance of ocular manifestations in granulomatosis with polyangiitis: association with sinonasal involvement and damage by Hinojosa-Azaola, Andrea, García-Castro, Annette, Juárez-Flores, Alejandra, Recillas-Gispert, Claudia

“…Ocular involvement is present in 50–60% of granulomatosis with polyangiitis (GPA) patients and can affect any part of the ocular globe. The present study…”
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RB1 alteration and poor prognosis in women with high-grade neuroendocrine carcinoma of the uterine cervix: a NeCTuR study by Flores Legarreta, Alejandra, Salvo, Gloria, Gonzales, Naomi R, Chisholm, Gary, Hillman, R Tyler, Frumovitz, Michael

“…To describe the gene alteration status in high-grade neuroendocrine cervical carcinoma (NECC) specimens and to explore the potential association of unique gene…”
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Identification of epigenetic silencing of the SFRP2 gene in colorectal cancer as a clinical biomarker and molecular significance by Boughanem, Hatim, Pilo, Jesús, García-Flores, Libia Alejandra, Arranz, Isabel, Ramos-Fernandez, María, Ortega-Castan, María, Crujeiras, Ana B, Sandoval, Juan, Macias-Gonzalez, Manuel

“…Several studies have suggested secreted frizzled-related protein 2 (SFRP2) gene as a potential clinical biomarker in colorectal cancer (CRC). However, its…”
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High-intensity interval training reduces the induction of neutrophil extracellular traps in older men using live-neutrophil imaging as biosensor by Vidal-Seguel, Nicolás, Cabrera, Camilo, Ferrada, Luciano, Artigas-Arias, Macarena, Alegría-Molina, Andrea, Sanhueza, Sergio, Flores, Alejandra, Huard, Nolberto, Sapunar, Jorge, Salazar, Luis A., McGregor, Reuben, Nova-Lamperti, Estefanía, Marzuca-Nassr, Gabriel Nasri

“…Neutrophil extracellular trap formation (NETosis) is a mechanism used by neutrophils to capture pathogens with their own DNA. However, the exacerbation of this…”
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8-Oxoguanine DNA Glycosylase 1 Upregulation as a Risk Factor for Obesity and Colorectal Cancer by Pilo, Jesús, García-Flores, Libia Alejandra, Clemente-Postigo, Mercedes, Arranz-Salas, Isabel, Alcaide, Julia, Ramos-Fernandez, Maria, Lozano, José, Boughanem, Hatim, Kompella, Pallavi, Macías-González, Manuel

“…DNA damage has been extensively studied as a potentially helpful tool in assessing and preventing cancer, having been widely associated with the deregulation…”
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Multifunctional human monoclonal antibody combination mediates protection against Rift Valley fever virus at low doses by Chapman, Nathaniel S., Hulswit, Ruben J. G., Westover, Jonna L. B., Stass, Robert, Paesen, Guido C., Binshtein, Elad, Reidy, Joseph X., Engdahl, Taylor B., Handal, Laura S., Flores, Alejandra, Gowen, Brian B., Bowden, Thomas A., Crowe, James E.

“…The zoonotic Rift Valley fever virus (RVFV) can cause severe disease in humans and has pandemic potential, yet no approved vaccine or therapy exists. Here we…”
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Geographic distribution and endemism of Bromeliaceae from the Western Sierra-Coast region of Jalisco, Mexico by Flores-Argüelles, Alejandra, López-Ferrari, Ana Rosa, Espejo-Serna, Adolfo

“…Background: Bromeliaceae are widespread in Mexico and present in all types of vegetation. A high number of species are restricted to the country. Jalisco is…”
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Nedd8-Activating Enzyme Is a Druggable Host Dependency Factor of Human and Mouse Cytomegalovirus by Flores-Martínez, Yulia Alejandra, Le-Trilling, Vu Thuy Khanh, Trilling, Mirko

“…Human cytomegalovirus causes diseases in individuals with insufficient immunity. Cytomegaloviruses exploit the ubiquitin proteasome pathway to manipulate the…”
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A shell matrix protein of Pinctada mazatlanica produces nacre platelets in vitro by Rivera-Perez, Crisalejandra, Flores-Sánchez, Iliana Alejandra, Ojeda Ramírez de Areyano, Josafat Jehu, Rojas Posadas, Delia Irene, Hernández-Saavedra, Norma Y.

“…Nacre is the main component of the pearl oyster shells and it is synthesized by specialized soluble and insoluble shell matrix proteins. Insoluble proteins…”
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Deficient glucose uptake is linked to impaired Glut1 expression upon CD3/CD28 stimulation in memory T cells from pleural effusions secondary to lung cancer by Prado‐Garcia, Heriberto, Romero‐Garcia, Susana, Castro‐Flores, Daniela Alejandra, Rumbo‐Nava, Uriel

“…Glucose and nutrient uptake is essential in supporting T cell activation and is increased upon CD3/CD28 stimulation. As T cells from pleural effusions…”
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Diversity and Vertical Distribution of Epiphytic Angiosperms, in Natural and Disturbed Forest on the Northern Coast of Jalisco, Mexico by Flores-Argüelles, Alejandra, Espejo-Serna, Adolfo, López-Ferrari, Ana Rosa, Krömer, Thorsten

“…Background and AimsEpiphytes are an important component of tropical forests, also they are sensitive to disturbance and deforestation caused by humans, since…”
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