Search Results - "FLOHE, S"

Human Heat Shock Protein 60 Induces Maturation of Dendritic Cells Versus a Th1-Promoting Phenotype by Flohe, Stefanie B, Bruggemann, Jutta, Lendemans, Sven, Nikulina, Marina, Meierhoff, Guido, Flohe, Sascha, Kolb, Hubert

“…Heat shock protein (HSP) 60 nonspecifically activates cells of the innate immune system. In the present study, we characterized the effects of human HSP60…”
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Recommendations for Releasing the Pelvic Binder After a Non-Invasive Pelvic Stabilisation Procedure Under Emergency Room Conditions by Schweigkofler, U, Wohlrath, B, Paffrath, T, Flohé, S, Wincheringer, D, Hoffmann, R, Trentzsch, H

“…Severe brain, thoracic and intrapelvic injuries, as well as heavy bleeding, are the main causes of death in patients with major trauma. Unstable pelvic ring…”
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Immune response of severely injured patients--influence of surgical intervention and therapeutic impact by Flohé, S, Flohé, S B, Schade, F U, Waydhas, C

“…[corrected] Severe injury leads to a severe deterioration of the patients' immune response. The changes of the immune response after severe injury include a…”
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Dendritic cells during polymicrobial sepsis rapidly mature but fail to initiate a protective Th1-type immune response by Flohe, S B, Agrawal, H, Schmitz, D, Gertz, M, Flohe, S, Schade, FU

“…Polymicrobial sepsis is associated with immunosuppression caused by the predominance of anti‐inflammatory mediators and profound loss of lymphocytes through…”
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Emergency intervention rate in the emergency room depending on the alerting criteria : Prospective data analysis of a supraregional trauma center by Heindl, B, Trentzsch, H, Flohé, S

“…Trauma team alert (TTA) to the emergency room (ER) takes place in the event of disturbed vital signs or serious injuries (A criteria) or after a dangerous…”
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Are large fracture trials really possible? What we have learned from the randomized controlled damage control study? by Steinhausen, Eva, Bouillon, Bertil, Rixen, Dieter

“…Purpose Although they are considered the ‘gold standard’ of evidence-based medicine, randomized controlled trials are still a rarity in orthopedic surgery. In…”
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Expression and function of Toll‐like receptor 9 in severely injured patients prone to sepsis by Baiyee, E. E., Flohe, S., Lendemans, S., Bauer, S., Mueller, N., Kreuzfelder, E., Grosse‐Wilde, H.

“…Summary The purpose of this prospective study was to enumerate Toll‐like receptor 9 (TLR9)+ cells and measure their function using synthetic oligonucleotides…”
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Preclinical and intrahospital management of mass casualties and terrorist incidents by Franke, A, Bieler, D, Friemert, B, Kollig, E, Flohe, S

“…Due to the recent terrorist attacks in Paris, Brussels, Ansbach, Munich, Berlin and more recently Manchester and London, terrorism is realized as a present…”
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Limited volume resuscitation in hypotensive elderly multiple trauma is safe and prevents early clinical dilutive coagulopathy – A matched pair analysis from TraumaRegister DGU by Leenen, M, Scholz, A, Lefering, R, Flohé, S

“…Abstract Background The use of permissive hypotension includes a restrained volume preclinical therapy. However, in the elderly patients, this approach has…”
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Damage Control Orthopedics by Bieler, D., Franke, A., Flohé, S.

“…Purpose of Review This review focuses on the concept of damage control orthopedics (DCO), the staged procedure to prevent the multiple injury patients from…”
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Future perspective of the TraumaRegister DGU® : Further development, additional modules and potential limits by Flohé, S, Matthes, G, Maegele, M, Huber-Wagner, S, Nienaber, U, Lefering, R, Paffrath, T

“…Since its founding in 1993 the TraumaRegister DGU® has become one of the largest registries especially in terms of data diversity. Since the introduction of…”
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Immunological reactions secondary to blood transfusion by Flohé, S, Kobbe, P, Nast-Kolb, D

“…Summary Multiply injured patients are at risk of developing the systemic inflammatory response syndrome, which may involve multiple organ failure,…”
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Heat Shock Protein 60 Is a Putative Endogenous Ligand of the Toll-Like Receptor-4 Complex by Ohashi, K, Burkart, V, Flohe, S, Kolb, H

“…Human heat shock protein 60 (hsp60) elicits a potent proinflammatory response in cells of the innate immune system and therefore has been proposed as a danger…”
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Intensive care medicine -- update 2005 by Flohé, S, Lendemans, S, Schmitz, D, Waydhas, C

“…This manuscript gives a review about important studies addressing problems in intensive care medicine that have been published in journals focussing on…”
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Fractures of the patella by Wild, M, Windolf, J, Flohé, S

“…Fractures of the patella account for approximately 0.5% to 1.5% of all skeletal injuries. The diagnosis is made by means of the mechanism of injury, physical…”
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Essential measures for prehospital treatment of severely injured patients: The trauma care bundle by Matthes, G, Trentzsch, H, Wölfl, C G, Paffrath, T, Flohe, S, Schweigkofler, U, Ekkernkamp, A, Schulz-Drost, S

“…In order to ensure adequate treatment and to avoid complications, care bundles are increasingly being implemented. These are comprehensive and evidence-based…”
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Current standard of care for initial management of open fractures in emergency departments : A nationwide survey in German trauma centers by Reith, G, Wyen, H, Wafaisade, A, Paffrath, T, Flohé, S, Bouillon, B, Maegele, M, Probst, C

“…Limiting the morbidity of open fractures requires highly specific initial treatment. In addition to a stringent surgical strategy, correct antibiotic…”
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Antigen‐pulsed epidermal Langerhans cells protect susceptible mice from infection with the intracellular parasite Leishmania major by Flohé, Stefanie B., Bauer, Carmen, Flohé, Sascha, Moll, Heidrun

“…Efficient vaccination against the parasite Leishmania major, the causative agent of human cutaneous leishmaniasis, requires the development of a…”
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Current practice in coagulation and transfusion therapy in multiple trauma patients: A German nation-wide online survey by Wafaisade, A, Wyen, H, Mutschler, M, Lendemans, S, Bouillon, B, Flohe, S, Paffrath, T, Maegele, M, Tjardes, T, Probst, C

“…In recent years, the treatment of trauma-associated coagulopathy and bleeding has advanced enormously. The aim of this study was to assess the current practice…”
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Surgical management of life-threatening injuries by Flohé, S, Nast-Kolb, D

“…Life-threatening situations after multiple trauma which then require interruption of the diagnostic algorithm and immediate surgical treatment after admission…”
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