Search Results - "FLICKER, Leon"

Clinical systematic reviews – a brief overview by Iddagoda, Mayura Thilanka, Flicker, Leon

“…Objective Systematic reviews answer research questions through a defined methodology. It is a complex task and multiple articles need to be referred to acquire…”
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Deprescribing in Frail Older People: A Randomised Controlled Trial by Potter, Kathleen, Flicker, Leon, Page, Amy, Etherton-Beer, Christopher

“…Deprescribing has been proposed as a way to reduce polypharmacy in frail older people. We aimed to reduce the number of medicines consumed by people living in…”
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Validation of the FRAIL Scale in a Cohort of Older Australian Women by Lopez, Derrick, Flicker, Leon, Dobson, Annette

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Fall rates in hospital rehabilitation units after individualised patient and staff education programmes: a pragmatic, stepped-wedge, cluster-randomised controlled trial by Hill, Anne-Marie, Dr, McPhail, Steven M, PhD, Waldron, Nicholas, MD, Etherton-Beer, Christopher, Prof, Ingram, Katharine, MBBS, Flicker, Leon, Prof, Bulsara, Max, Prof, Haines, Terry P, Prof

“…Summary Background Falls are the most frequent adverse events that are reported in hospitals. We examined the effectiveness of individualised falls-prevention…”
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Hearing loss and the risk of dementia in later life by Ford, Andrew H., Hankey, Graeme J., Yeap, Bu B., Golledge, Jonathan, Flicker, Leon, Almeida, Osvaldo P.

“…•Hearing loss is a potentially modifiable risk factor for dementia.•In our cohort, men with hearing loss had a 69% greater hazard of developing dementia than…”
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Optimisation of medications used in residential aged care facilities: a systematic review and meta-analysis of randomised controlled trials by Almutairi, Hend, Stafford, Andrew, Etherton-Beer, Christopher, Flicker, Leon

“…Frail older adults living in residential aged care facilities (RACFs) usually experience comorbidities and are frequently prescribed multiple medications. This…”
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Systematic review and meta-analysis of randomized placebo-controlled trials of folate and vitamin B12 for depression by Almeida, Osvaldo P, Ford, Andrew H, Flicker, Leon

“…Folate and vitamin B12 insufficiencies have been associated with increased risk of depression. This systematic review aimed to clarify if, compared with…”
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A Pooled Analysis of Vitamin D Dose Requirements for Fracture Prevention by Bischoff-Ferrari, Heike A, Willett, Walter C, Orav, Endel J, Lips, Paul, Meunier, Pierre J, Lyons, Ronan A, Flicker, Leon, Wark, John, Jackson, Rebecca D, Cauley, Jane A, Meyer, Haakon E, Pfeifer, Michael, Sanders, Kerrie M, Stähelin, Hannes B, Theiler, Robert, Dawson-Hughes, Bess

“…This study of pooled data from trials of oral vitamin D supplementation examined the incidence of hip and nonvertebral fractures in persons 65 years of age or…”
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Depression, Frailty, and All-Cause Mortality: A Cohort Study of Men Older than 75 Years by Almeida, Osvaldo P., MD, PhD, Hankey, Graeme J., MD, Yeap, Bu B., MBBS, PhD, Golledge, Jonathan, MChir, Norman, Paul E., DS, Flicker, Leon, MBBS, PhD

“…Abstract Background Depression is associated with increased mortality, but it is unclear if this relationship is truly causal. Objectives To determine the…”
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The longitudinal association between natural outdoor environments and mortality in 9218 older men from Perth, Western Australia by Zijlema, Wilma L., Stasinska, Ania, Blake, David, Dirgawati, Mila, Flicker, Leon, Yeap, Bu B., Golledge, Jonathan, Hankey, Graeme J., Nieuwenhuijsen, Mark, Heyworth, Jane

“…Natural outdoor environments may mitigate harmful environmental factors associated with city living. We studied the longitudinal relationship between natural…”
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Calcium supplementation and the risks of atherosclerotic vascular disease in older women: Results of a 5‐year RCT and a 4.5‐year follow‐up by Lewis, Joshua R, Calver, Janine, Zhu, Kun, Flicker, Leon, Prince, Richard L

“…Concern has been expressed that calcium supplementation, a key intervention for preventing osteoporotic fracture in older women, may increase the risk of…”
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Evaluation of RESPOND, a patient-centred program to prevent falls in older people presenting to the emergency department with a fall: A randomised controlled trial by Barker, Anna, Cameron, Peter, Flicker, Leon, Arendts, Glenn, Brand, Caroline, Etherton-Beer, Christopher, Forbes, Andrew, Haines, Terry, Hill, Anne-Marie, Hunter, Peter, Lowthian, Judy, Nyman, Samuel R, Redfern, Julie, Smit, De Villiers, Waldron, Nicholas, Boyle, Eileen, MacDonald, Ellen, Ayton, Darshini, Morello, Renata, Hill, Keith

“…Falls are a leading reason for older people presenting to the emergency department (ED), and many experience further falls. Little evidence exists to guide…”
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Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: a meta-analysis of genetic studies and randomised trials by Holmes, Michael V, DLSHTM, Newcombe, Paul, PhD, Hubacek, Jaroslav A, PhD, Sofat, Reecha, PhD, Ricketts, Sally L, PhD, Cooper, Jackie, MSc, Breteler, Monique MB, Prof, Bautista, Leonelo E, DrPH, Sharma, Pankaj, MD, Whittaker, John C, Prof, Smeeth, Liam, Prof, Fowkes, F Gerald R, Prof, Algra, Ale, Prof, Shmeleva, Veronika, MD, Szolnoki, Zoltan, PhD, Roest, Mark, PhD, Linnebank, Michael, MD, Zacho, Jeppe, MD, Nalls, Michael A, PhD, Singleton, Andrew B, PhD, Ferrucci, Luigi, MD, Hardy, John, Prof, Worrall, Bradford B, MD, Rich, Stephen S, Prof, Matarin, Mar, PhD, Norman, Paul E, FRACS, Flicker, Leon, FRACP, Almeida, Osvaldo P, Prof, van Bockxmeer, Frank M, Prof, Shimokata, Hiroshi, Prof, Khaw, Kay-Tee, Prof, Wareham, Nicholas J, Prof, Bobak, Martin, Prof, Sterne, Jonathan AC, Prof, Smith, George Davey, Prof, Talmud, Philippa J, Prof, van Duijn, Cornelia, Prof, Humphries, Steve E, Prof, Price, Jackie F, FFPH, Ebrahim, Shah, Prof, Lawlor, Debbie A, Prof, Hankey, Graeme J, FRACP, Meschia, James F, Prof, Sandhu, Manjinder S, PhD, Hingorani, Aroon D, Prof, Casas, Juan P, Dr

“…Summary Background The MTHFR 677C→T polymorphism has been associated with raised homocysteine concentration and increased risk of stroke. A previous overview…”
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Body Mass Index and Survival in Men and Women Aged 70 to 75 by Flicker, Leon, McCaul, Kieran A., Hankey, Graeme J., Jamrozik, Konrad, Brown, Wendy J., Byles, Julie E., Almeida, Osvaldo P.

“…OBJECTIVES: To examine in an older population all‐cause and cause‐specific mortality associated with underweight (body mass index (BMI)<18.5), normal weight…”
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Lower Testosterone Levels Predict Incident Stroke and Transient Ischemic Attack in Older Men by Yeap, Bu B., Hyde, Zoë, Almeida, Osvaldo P., Norman, Paul E., Chubb, S. A. Paul, Jamrozik, Konrad, Flicker, Leon, Hankey, Graeme J.

“…Context: Lower circulating testosterone concentrations are associated with metabolic syndrome, type 2 diabetes, carotid intima-media thickness, and aortic and…”
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Long-term exposure to outdoor air pollution and risk factors for cardiovascular disease within a cohort of older men in Perth by Vander Hoorn, Stephen, Murray, Kevin, Nedkoff, Lee, Hankey, Graeme J, Flicker, Leon, Yeap, Bu B, Almeida, Osvaldo P, Norman, Paul, Brunekreef, Bert, Nieuwenhuijsen, Mark, Heyworth, Jane

“…While there is clear evidence that high levels of pollution are associated with increased all-cause mortality and cardiovascular mortality and morbidity, the…”
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Reduced serum total osteocalcin is associated with metabolic syndrome in older men via waist circumference, hyperglycemia, and triglyceride levels by Yeap, Bu B, Chubb, S A Paul, Flicker, Leon, McCaul, Kieran A, Ebeling, Peter R, Beilby, John P, Norman, Paul E

“…ObjectiveBone-derived undercarboxylated osteocalcin regulates insulin secretion and sensitivity in mice, and reduced serum total osteocalcin (TOC) is…”
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Prospective longitudinal study of testosterone and incident depression in older men: The Health In Men Study by Ford, Andrew H, Yeap, Bu B, Flicker, Leon, Hankey, Graeme J, Chubb, S.A. Paul, Handelsman, David J, Golledge, Jonathan, Almeida, Osvaldo P

“…Highlights • Depression in older men has been associated with low circulating testosterone but data from prospective studies is limited and no previous studies…”
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Let's CHAT (community health approaches to) dementia in Aboriginal and Torres Strait Islander communities: protocol for a stepped wedge cluster randomised controlled trial by Bradley, Kate, Smith, Robyn, Hughson, Jo-Anne, Atkinson, David, Bessarab, Dawn, Flicker, Leon, Radford, Kylie, Smith, Kate, Strivens, Edward, Thompson, Sandra, Blackberry, Irene, LoGiudice, Dina

“…Documented rates of dementia and cognitive impairment not dementia (CIND) in older Aboriginal and Torres Strait Islander Peoples is 3-5 times higher than the…”
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Physical activity and all-cause mortality in older women and men by Brown, Wendy J, McLaughlin, Deirdre, Leung, Janni, McCaul, Kieran A, Flicker, Leon, Almeida, Osvaldo P, Hankey, Graeme J, Lopez, Derrick, Dobson, Annette J

“…Regular physical activity is associated with reduced risk of mortality in middle-aged adults; however, associations between physical activity and mortality in…”
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