Search Results - "FLETCHER, Linda"
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The use of critical thinking in higher education in relation to the international student: Shifting policy and practice
Published in British educational research journal (01-12-2016)“…Academic staff working within Western higher education institutions (HEIs), have a responsibility to encourage the continuous critique of knowledge and values,…”
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Desirable performance characteristics for BCR-ABL measurement on an international reporting scale to allow consistent interpretation of individual patient response and comparison of response rates between clinical trials
Published in Blood (15-10-2008)“…An international basis for comparison of BCR-ABL mRNA levels is required for the common interpretation of data derived from individual laboratories. This will…”
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Excess iron modulates endoplasmic reticulum stress-associated pathways in a mouse model of alcohol and high-fat diet-induced liver injury
Published in Laboratory investigation (01-12-2013)“…Endoplasmic reticulum (ER) stress is an important pathogenic mechanism for alcoholic (ALD) and nonalcoholic fatty liver disease (NAFLD). Iron overload is an…”
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4
Power, agency and middle leadership in English primary schools
Published in British educational research journal (01-10-2011)“…English primary schools are considered quasi-collegial institutions within which staff communicate regularly and openly. The activities of staff, however, are…”
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ELF score ≥9.8 indicates advanced hepatic fibrosis and is influenced by age, steatosis and histological activity
Published in Liver international (01-06-2015)“…Background & Aims There is increasing need to identify individuals with advanced liver fibrosis, who are at risk of complications such as hepatocellular…”
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The Enhanced liver fibrosis score is associated with clinical outcomes and disease progression in patients with chronic liver disease
Published in Liver international (01-03-2016)“…Background and Aims Current tools for risk stratification of chronic liver disease subjects are limited. We aimed to determine whether the serum‐based ELF…”
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Rapamycin inhibits hepatic fibrosis in rats by attenuating multiple profibrogenic pathways
Published in Liver transplantation (01-10-2009)“…Hepatic stellate cell transdifferentiation, epithelial‐mesenchymal cell transition, and the ductular reaction each contribute to the development of hepatic…”
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Induction of Meal-related Symptoms as a Novel Mechanism of Action of the Duodenal-Jejunal Bypass Sleeve
Published in Journal of clinical gastroenterology (01-07-2020)“…BACKGROUND:Treatment with a duodenal-jejunal bypass sleeve (DJBS) induces clinically significant weight loss, but little is known about the mechanisms of…”
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Serum ferritin concentration predicts mortality in patients awaiting liver transplantation
Published in Hepatology (Baltimore, Md.) (01-05-2010)“…Additional markers are required to identify patients on the orthotopic liver transplant (OLT) waiting list at increased risk of death and adverse clinical…”
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Validation of EpiTRAQ, a transition readiness assessment tool for adolescents and young adults with epilepsy
Published in Epilepsia open (01-09-2020)“…Objective To design and validate a transition readiness assessment tool for adolescents and young adults with epilepsy and without intellectual disability…”
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The serum hepcidin:ferritin ratio is a potential biomarker for cirrhosis
Published in Liver international (01-10-2012)“…Background Serum hepcidin concentration is potentially affected by inflammation and iron stores in chronic liver disease (CLD), but little is known about the…”
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Reflecting on reflective practices within peer observation
Published in Studies in higher education (Dorchester-on-Thames) (01-04-2005)“…Peer Observation of Teaching is one process employed within higher education establishments in Britain that can be instrumental in developing the reflective…”
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Intravital multiphoton microscopy can model uptake and excretion of fluorescein in hepatic ischemia-reperfusion injury
Published in Journal of biomedical optics (01-10-2013)“…The liver is important in the biotransformation of various drugs, where hepatic transporters facilitate uptake and excretion. Ischemia-reperfusion (I/R) injury…”
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14
Harmonization of molecular monitoring of chronic myeloid leukemia therapy in Japan
Published in International journal of clinical oncology (01-12-2012)“…Background Real-time quantitative polymerase chain reaction (RQ-PCR) has been widely used for molecular monitoring for patients with chronic myeloid leukemia…”
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Hepcidin Is Down-regulated in Alcoholic Liver Injury: Implications for the Pathogenesis of Alcoholic Liver Disease
Published in Alcoholism, clinical and experimental research (01-01-2006)“…Background: Alcoholic liver disease is known to be associated with abnormal iron homeostasis, and iron metabolism itself is regulated by the liver‐derived…”
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Excess alcohol greatly increases the prevalence of cirrhosis in hereditary hemochromatosis
Published in Gastroenterology (New York, N.Y. 1943) (01-02-2002)“…Background & Aims:The progression of fibrosis to cirrhosis is the most significant prognostic factor in hereditary hemochromatosis. We aimed to determine the…”
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Dysbiosis of the Duodenal Mucosal Microbiota Is Associated With Increased Small Intestinal Permeability in Chronic Liver Disease
Published in Clinical and translational gastroenterology (01-08-2019)“…Chronic liver disease (CLD) is associated with both alterations of the stool microbiota and increased small intestinal permeability. However, little is known…”
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Diagnostic sensitivity of carbohydrate deficient transferrin in heavy drinkers
Published in BMC gastroenterology (22-05-2014)“…Carbohydrate deficient transferrin (CDT) is the most specific serum biomarker of heavy alcohol consumption, defined as ≥ 350-420 g alcohol/week. Despite…”
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Steatosis Is a Cofactor in Liver Injury in Hemochromatosis
Published in Gastroenterology (New York, N.Y. 1943) (01-12-2005)“…Background & Aims: Obesity-related steatosis is an increasingly common histologic finding and often coexists with other chronic liver diseases. Although…”
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Chasing improved pupil performance: The impact of policy change on school educators' perceptions of their professional identity, the case of further change in English schools
Published in British educational research journal (01-12-2010)“…Changes in education systems across Europe are a response to perceived needs to improve academic performance. The recent workforce remodelling agenda in…”
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