Search Results - "FLENTJE, Michael"

Randomized Phase II Trial of Chemoradiotherapy Plus Induction or Consolidation Chemotherapy as Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer: CAO/ARO/AIO-12 by Fokas, Emmanouil, Allgäuer, Michael, Polat, Bülent, Klautke, Gunther, Grabenbauer, Gerhard G, Fietkau, Rainer, Kuhnt, Thomas, Staib, Ludger, Brunner, Thomas, Grosu, Anca-Ligia, Schmiegel, Wolff, Jacobasch, Lutz, Weitz, Jürgen, Folprecht, Gunnar, Schlenska-Lange, Anke, Flentje, Michael, Germer, Christoph-Thomas, Grützmann, Robert, Schwarzbach, Matthias, Paolucci, Vittorio, Bechstein, Wolf O, Friede, Tim, Ghadimi, Michael, Hofheinz, Ralf-Dieter, Rödel, Claus

“…Total neoadjuvant therapy is a new paradigm for rectal cancer treatment. Optimal scheduling of preoperative chemoradiotherapy (CRT) and chemotherapy remains to…”
Get full text

Practice recommendations for lung cancer radiotherapy during the COVID-19 pandemic: An ESTRO-ASTRO consensus statement by Guckenberger, Matthias, Belka, Claus, Bezjak, Andrea, Bradley, Jeffrey, Daly, Megan E., DeRuysscher, Dirk, Dziadziuszko, Rafal, Faivre-Finn, Corinne, Flentje, Michael, Gore, Elizabeth, Higgins, Kristin A., Iyengar, Puneeth, Kavanagh, Brian D, Kumar, Sameera, Le Pechoux, Cecile, Lievens, Yolande, Lindberg, Karin, McDonald, Fiona, Ramella, Sara, Rengan, Ramesh, Ricardi, Umberto, Rimner, Andreas, Rodrigues, George B., Schild, Steven E., Senan, Suresh, Simone II, Charles B., Slotman, Ben J., Stuschke, Martin, Videtic, Greg, Widder, Joachim, Yom, Sue S., Palma, David

“…•Recommendations for risk-mitigation pandemic scenario:•Do not to compromise the prognosis of lung cancer patients by departing from guideline-recommended…”
Get full text

Potential of Adaptive Radiotherapy to Escalate the Radiation Dose in Combined Radiochemotherapy for Locally Advanced Non–Small Cell Lung Cancer by Guckenberger, Matthias, M.D, Wilbert, Juergen, Ph.D, Richter, Anne, M.Sc, Baier, Kurt, M.Sc, Flentje, Michael, M.D

“…Purpose To evaluate the potential of adaptive radiotherapy (ART) for advanced-stage non–small cell lung cancer (NSCLC) in terms of lung sparing and dose…”
Get full text

Practice Recommendations for Lung Cancer Radiotherapy During the COVID-19 Pandemic: An ESTRO-ASTRO Consensus Statement by Guckenberger, Matthias, Belka, Claus, Bezjak, Andrea, Bradley, Jeffrey, Daly, Megan E., DeRuysscher, Dirk, Dziadziuszko, Rafal, Faivre-Finn, Corinne, Flentje, Michael, Gore, Elizabeth, Higgins, Kristin A., Iyengar, Puneeth, Kavanagh, Brian D., Kumar, Sameera, Le Pechoux, Cecile, Lievens, Yolande, Lindberg, Karin, McDonald, Fiona, Ramella, Sara, Rengan, Ramesh, Ricardi, Umberto, Rimner, Andreas, Rodrigues, George B., Schild, Steven E., Senan, Suresh, Simone II, Charles B., Slotman, Ben J., Stuschke, Martin, Videtic, Greg, Widder, Joachim, Yom, Sue S., Palma, David

“…The COVID-19 pandemic has caused radiotherapy resource pressures and led to increased risks for lung cancer patients and healthcare staff. An international…”
Get full text

Collective cancer invasion forms an integrin-dependent radioresistant niche by Haeger, Anna, Alexander, Stephanie, Vullings, Manon, Kaiser, Fabian M P, Veelken, Cornelia, Flucke, Uta, Koehl, Gudrun E, Hirschberg, Markus, Flentje, Michael, Hoffman, Robert M, Geissler, Edward K, Kissler, Stephan, Friedl, Peter

“…Cancer fatalities result from metastatic dissemination and therapy resistance, both processes that depend on signals from the tumor microenvironment. To…”
Get full text

Trim33 masks a non-transcriptional function of E2f4 in replication fork progression by Rousseau, Vanessa, Einig, Elias, Jin, Chao, Horn, Julia, Riebold, Mathias, Poth, Tanja, Jarboui, Mohamed-Ali, Flentje, Michael, Popov, Nikita

“…Replicative stress promotes genomic instability and tumorigenesis but also presents an effective therapeutic endpoint, rationalizing detailed analysis of…”
Get full text

Is a single arc sufficient in volumetric-modulated arc therapy (VMAT) for complex-shaped target volumes? by Guckenberger, Matthias, Richter, Anne, Krieger, Thomas, Wilbert, Juergen, Baier, Kurt, Flentje, Michael

“…Abstract Purpose To compare step-and-shoot intensity-modulated radiotherapy (ss-IMRT) with volumetric-modulated arc therapy (VMAT) for complex-shaped target…”
Get full text

FocAn: automated 3D analysis of DNA repair foci in image stacks acquired by confocal fluorescence microscopy by Memmel, Simon, Sisario, Dmitri, Zimmermann, Heiko, Sauer, Markus, Sukhorukov, Vladimir L, Djuzenova, Cholpon S, Flentje, Michael

“…Phosphorylated histone H2AX, also known as γH2AX, forms μm-sized nuclear foci at the sites of DNA double-strand breaks (DSBs) induced by ionizing radiation and…”
Get full text

Stereotactic Body Radiotherapy (SBRT) for medically inoperable lung metastases—A pooled analysis of the German working group “stereotactic radiotherapy” by Rieber, Juliane, Streblow, Jan, Uhlmann, Lorenz, Flentje, Michael, Duma, Marciana, Ernst, Iris, Blanck, Oliver, Wittig, Andrea, Boda-Heggemann, Judit, Krempien, Robert, Lohaus, Fabian, Klass, Nathalie Desirée, Eble, Michael J, Imhoff, Detlef, Kahl, Henning, Petersen, Cordula, Gerum, Sabine, Henkenberens, Christoph, Adebahr, Sonja, Hass, Peter, Schrade, Elsge, Wendt, Thomas G, Hildebrandt, Guido, Andratschke, Nicolaus, Sterzing, Florian, Guckenberger, Matthias

“…Highlights • SBRT for inoperable pulmonary metastases achieved excellent LC and promising OS. • LC was mainly influenced by BED at both isocenter and…”
Get full text

Stereotactic body radiation therapy in the re-irradiation situation--a review by Mantel, Frederick, Flentje, Michael, Guckenberger, Matthias

“…Although locoregional relapse is frequent after definitive radiotherapy (RT) or multimodal treatments, re-irradiation is only performed in few patients even in…”
Get full text

Influence of Institutional Experience and Technological Advances on Outcome of Stereotactic Body Radiation Therapy for Oligometastatic Lung Disease by Rieber, Juliane, MD, Abbassi-Senger, Nasrin, MD, Adebahr, Sonja, MD, Andratschke, Nicolaus, MD, Blanck, Oliver, PhD, Duma, Marciana, MD, Eble, Michael J., MD, Ernst, Iris, MD, Flentje, Michael, MD, Gerum, Sabine, MD, Hass, Peter, MD, Henkenberens, Christoph, MD, Hildebrandt, Guido, MD, Imhoff, Detlef, MD, Kahl, Henning, MD, Klass, Nathalie Desirée, MD, Krempien, Robert, MD, Lohaus, Fabian, MD, Lohr, Frank, MD, Petersen, Cordula, MD, Schrade, Elsge, MD, Streblow, Jan, Uhlmann, Lorenz, Wittig, Andrea, MD, Sterzing, Florian, MD, Guckenberger, Matthias, MD

“…Purpose Many technological and methodical advances have made stereotactic body radiotherapy (SBRT) more accurate and more efficient during the last years. This…”
Get full text

Dose–response relationship for radiation-induced pneumonitis after pulmonary stereotactic body radiotherapy by Guckenberger, Matthias, Baier, Kurt, Polat, Buelent, Richter, Anne, Krieger, Thomas, Wilbert, Juergen, Mueller, Gerd, Flentje, Michael

“…Abstract Purpose To evaluate dosimetric factors predictive for radiation-induced pneumonitis (RP) after pulmonary stereotactic body radiotherapy (SBRT)…”
Get full text

Applicability of the linear-quadratic formalism for modeling local tumor control probability in high dose per fraction stereotactic body radiotherapy for early stage non-small cell lung cancer by Guckenberger, Matthias, Klement, Rainer Johannes, Allgäuer, Michael, Appold, Steffen, Dieckmann, Karin, Ernst, Iris, Ganswindt, Ute, Holy, Richard, Nestle, Ursula, Nevinny-Stickel, Meinhard, Semrau, Sabine, Sterzing, Florian, Wittig, Andrea, Andratschke, Nicolaus, Flentje, Michael

“…Abstract Background and purpose To compare the linear-quadratic (LQ) and the LQ-L formalism (linear cell survival curve beyond a threshold dose dT ) for…”
Get full text

Local tumor control probability modeling of primary and secondary lung tumors in stereotactic body radiotherapy by Guckenberger, Matthias, Klement, Rainer J, Allgäuer, Michael, Andratschke, Nicolaus, Blanck, Oliver, Boda-Heggemann, Judit, Dieckmann, Karin, Duma, Marciana, Ernst, Iris, Ganswindt, Ute, Hass, Peter, Henkenberens, Christoph, Holy, Richard, Imhoff, Detlef, Kahl, Henning K, Krempien, Robert, Lohaus, Fabian, Nestle, Ursula, Nevinny-Stickel, Meinhard, Petersen, Cordula, Semrau, Sabine, Streblow, Jan, Wendt, Thomas G, Wittig, Andrea, Flentje, Michael, Sterzing, Florian

“…Abstract Background and purpose To evaluate whether local tumor control probability (TCP) in stereotactic body radiotherapy (SBRT) varies between lung…”
Get full text

Health-related quality of life and clinical outcome after radiotherapy of patients with intracranial meningioma by Lisowski, Dominik, Trömel, Jannik, Lutyj, Paul, Lewitzki, Victor, Hartrampf, Philipp E., Polat, Bülent, Flentje, Michael, Tamihardja, Jörg

“…This retrospective, single-institutional study investigated long-term outcome, toxicity and health-related quality of life (HRQoL) in meningioma patients after…”
Get full text

Feasibility Study for Markerless Tracking of Lung Tumors in Stereotactic Body Radiotherapy by Richter, Anne, M.Sc, Wilbert, Juergen, Ph.D, Baier, Kurt, M.Sc, Flentje, Michael, M.D, Guckenberger, Matthias, M.D

“…Purpose To evaluate the feasibility and accuracy of a method for markerless tracking of lung tumors in electronic portal imaging device (EPID) movies and to…”
Get full text

Risk factors for vertebral compression fracture after spine stereotactic body radiation therapy: Long-term results of a prospective phase 2 study by Mantel, Frederick, Sweeney, Reinhart A, Klement, Rainer J, Hawkins, Maria A, Belderbos, Jose, Ahmed, Merina, Toussaint, André, Polat, Bülent, Flentje, Michael, Guckenberger, Matthias

“…Highlights•Vertebral compression fracture (VCF) occurred in 34.4% of treated lesions. •VCF was symptomatic in only 5% of patients. •Best predictors are:…”
Get full text

Radiotherapy in adrenocortical carcinoma by Polat, Buelent, Fassnacht, Martin, Pfreundner, Leo, Guckenberger, Matthias, Bratengeier, Klaus, Johanssen, Sarah, Kenn, Werner, Hahner, Stefanie, Allolio, Bruno, Flentje, Michael

“…Adrenocortical carcinoma (ACC) is a rare malignancy, and patients with ACC have a poor prognosis. Even after radical surgery, up to 85% of patients develop…”
Get full text

Dosimetric Evaluation of Commercially Available Flat vs. Self-Produced 3D-Conformal Silicone Boluses for the Head and Neck Region by Pollmann, Stephan, Toussaint, André, Flentje, Michael, Wegener, Sonja, Lewitzki, Victor

“…BackgroundBoluses are routinely used in radiotherapy to modify surface doses. Nevertheless, considerable dose discrepancies may occur in some cases due to fit…”
Get full text

New developments in locally advanced nonsmall cell lung cancer by Huber, Rudolf M, Kauffmann-Guerrero, Diego, Hoffmann, Hans, Flentje, Michael

“…Locally advanced nonsmall cell lung cancer, due to its varying prognosis, is grouped according to TNM stage IIIA, IIIB and IIIC. Developments over the last 3…”
Get full text